ID   A0A132AFP9_SARSC        Unreviewed;       506 AA.
AC   A0A132AFP9;
DT   11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT   11-MAY-2016, sequence version 1.
DT   28-JUN-2023, entry version 37.
DE   SubName: Full=Rab GTPase-binding effector protein 1-like protein {ECO:0000313|EMBL:KPM09812.1};
GN   ORFNames=QR98_0083570 {ECO:0000313|EMBL:KPM09812.1};
OS   Sarcoptes scabiei (Itch mite) (Acarus scabiei).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Acariformes; Sarcoptiformes; Astigmata; Psoroptidia; Sarcoptoidea;
OC   Sarcoptidae; Sarcoptinae; Sarcoptes.
OX   NCBI_TaxID=52283 {ECO:0000313|EMBL:KPM09812.1, ECO:0000313|Proteomes:UP000616769};
RN   [1] {ECO:0000313|EMBL:KPM09812.1, ECO:0000313|Proteomes:UP000616769}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Arlian Lab {ECO:0000313|EMBL:KPM09812.1};
RX   PubMed=26555130; DOI=10.1186/s13071-015-1198-2;
RA   Rider S.D.Jr., Morgan M.S., Arlian L.G.;
RT   "Draft genome of the scabies mite.";
RL   Parasit. Vectors 8:585-585(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KPM09812.1}.
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DR   EMBL; JXLN01014112; KPM09812.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A132AFP9; -.
DR   VEuPathDB; VectorBase:SSCA004265; -.
DR   OMA; TLCADNE; -.
DR   OrthoDB; 2904642at2759; -.
DR   Proteomes; UP000616769; Unassembled WGS sequence.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR   CDD; cd15739; FYVE_RABE_unchar; 1.
DR   Gene3D; 1.20.5.730; Single helix bin; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR003914; Rabaptin.
DR   InterPro; IPR015390; Rabaptin_Rab5-bd_dom.
DR   InterPro; IPR000306; Znf_FYVE.
DR   InterPro; IPR017455; Znf_FYVE-rel.
DR   InterPro; IPR011011; Znf_FYVE_PHD.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR31179:SF7; FYVE-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR31179; RAB GTPASE-BINDING EFFECTOR PROTEIN; 1.
DR   Pfam; PF01363; FYVE; 1.
DR   Pfam; PF09311; Rab5-bind; 1.
DR   SMART; SM00064; FYVE; 1.
DR   SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR   SUPFAM; SSF103652; G protein-binding domain; 1.
DR   PROSITE; PS50178; ZF_FYVE; 1.
PE   4: Predicted;
SQ   SEQUENCE   506 AA;  57817 MW;  A7A9F420805CCE1F CRC64;
     MSESLATVDS IVPDELITAQ SKNKIPDKSS QKCLESENES SDGTKNRPSN DSEEAFQTIQ
     IESSCSSFSS SDAEAKISLP FNSQGPMGSK LLIDSSSNQE SINHSSTNTI KQNELEKSNL
     NNSGQRKNMM ACEMCNNYEM QLQDMQYREA VLHISIGQYE KNIVKLKEDL KKEQSFENEL
     KSLSSQVDQG QNSFEKISNK FAKLNKSANS SIASLINQID KLKSDIVRLS SDNEKLIGRH
     LKKSREMLSE SISLPEDPEA LQFYCLQLRE DLIQALYNRE HLEETLRSEN IFLKEQLLGE
     QQSKENIEEN LAHENKTLLV RTQNLESELK NYKKNFDQIK IESKMFQNNY EDLSRSSSQK
     IEELETKLQI LSDNKAKSAE EIASLRSKVQ SLQIDLDNSE QVQRDFVKLS QSLQVQLEKI
     RQSDTEVRWQ HEDDVTECNG CKKCFHSRKE KINCMHCGRI FCSDCCSKSI QSGPNKRLFK
     VCQVCHTLLD HQTACWFVNE VPLSPT
//