ID A0A132PP38_9MYCO Unreviewed; 982 AA.
AC A0A132PP38;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Membrane protein {ECO:0000313|EMBL:KWX24100.1};
GN ORFNames=AFM11_12130 {ECO:0000313|EMBL:KWX24100.1};
OS Mycolicibacterium wolinskyi.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=59750 {ECO:0000313|EMBL:KWX24100.1, ECO:0000313|Proteomes:UP000070612};
RN [1] {ECO:0000313|EMBL:KWX24100.1, ECO:0000313|Proteomes:UP000070612}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC_01 {ECO:0000313|EMBL:KWX24100.1,
RC ECO:0000313|Proteomes:UP000070612};
RA de Man T.J., Perry K.A., Coulliette A.D., Jensen B., Toney N.C.,
RA Limbago B.M., Noble-Wang J.;
RT "A draft genome sequence of Mycobacterium wolinskyi.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KWX24100.1}.
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DR EMBL; LGTW01000006; KWX24100.1; -; Genomic_DNA.
DR RefSeq; WP_067848610.1; NZ_LGTW01000006.1.
DR AlphaFoldDB; A0A132PP38; -.
DR STRING; 59750.AWC31_09845; -.
DR PATRIC; fig|59750.3.peg.6505; -.
DR Proteomes; UP000070612; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000070612};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..229
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 241..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 290..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 317..341
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..427
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 564..586
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 593..612
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 632..655
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 676..695
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 701..723
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 47..366
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT DOMAIN 431..740
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT REGION 485..512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 754..827
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 849..982
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 493..507
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 754..773
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 863..879
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 901..917
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 921..940
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 954..982
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 982 AA; 105699 MW; 7E7EB19A8C5D9DD3 CRC64;
MFAWWGRTVY RFRYIVIGVM VALCLGGGVY GISLGDNVTQ SGFYDEGSQS VKASLLADEV
YGRDRTSHIV AILTPPDDKK VTDKAWQKSV TEELDKFVKD NPDQVVGWVG WLKAPDTTDP
TVSQMKTQDL RHTFISVPLN GENDDEILKN YQAIEPELRQ VNGGDIKLAG LNPLASELTG
TIGTDQKRAE IAIIPLVAVV LFFVFGGAVA AALPAIIGGL TIAGALGILR LTAEFGPVHF
FAQPVVTMMG LGIAIDYGLF IVSRFREELA EGYDTEAAVR RSVMTSGRTV AFSAVIIVAS
SMPLLLIPLG FLKSITYAII ASVMLAAILS ISVLPAVLGI LGARVDALGV RTLLKVPFLA
NWPFSRRIID WFAEKTQKTK TREEVERGFW GKLVNVVMKR PVAFATPILV VMTLLVIPIG
SLTLAGISEK YLPPDNSVRQ SQEEFDKLFP GFRTEQITMV MQREDGEPIT DSQIADMRAK
ALTVPGFTDP DNDPDAMWKE RPATDSGSKD PSVRVIQNGL VNRGDAATNI EGLRALQPPH
GITVYVGGTP ALEQDSIHSL FSRLPLMVTI LVITTTVLMF LAFGSIVLPI KAALMSALTL
GSTMGILTWM FVDGHGSGLL NYTPQPLMAP MIGLIIAVIW GLSTDYEVFL VSRMVEARER
GMSTAEAIRI GTATTGRLIT GAALVLAVVA GPFAFSDLVM MKYLAFGLLI ALLLDATVIR
MFLVPAIMKL LGDDCWWAPR WMKRIQEKIG LGETELPDER KRPTVREPAD DERALVGVGA
PPPPPRPHDP THPGVDPSRQ APPMRANAPS AAGTVRIGPP PQQAEEPATT RFAMARNAVR
NAVNSAVNTA TGNANAPTAR TPRPGAQPAP PPPPPPPGTP REEREIESWL GALRGGPANG
PAESTPPPPP PPARPSADAT RAMPQSRQAP GDNAPTTAFS AQRPPAGADP ATEKLNTRET
DEPKRRGGGM SAQDLLRREG RL
//
