ID A0A132SLE3_9MYCO Unreviewed; 487 AA.
AC A0A132SLE3;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=NAD-dependent succinate-semialdehyde dehydrogenase {ECO:0000313|EMBL:KWX59899.1};
GN ORFNames=ASJ79_09375 {ECO:0000313|EMBL:KWX59899.1};
OS Mycobacterium sp. NAZ190054.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1747766 {ECO:0000313|EMBL:KWX59899.1, ECO:0000313|Proteomes:UP000070146};
RN [1] {ECO:0000313|EMBL:KWX59899.1, ECO:0000313|Proteomes:UP000070146}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NAZ190054 {ECO:0000313|EMBL:KWX59899.1,
RC ECO:0000313|Proteomes:UP000070146};
RA Zhang Y., Guo Z.;
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KWX59899.1}.
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DR EMBL; LMVQ01000457; KWX59899.1; -; Genomic_DNA.
DR RefSeq; WP_067960956.1; NZ_LMVQ01000457.1.
DR AlphaFoldDB; A0A132SLE3; -.
DR OrthoDB; 6882680at2; -.
DR Proteomes; UP000070146; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd07103; ALDH_F5_SSADH_GabD; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR43353; SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43353:SF5; SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000070146}.
FT DOMAIN 30..481
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 261
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 487 AA; 50348 MW; 9452488D3E1C5146 CRC64;
MHTADVTADL IAGVDPRHGI LVGGLARTSA STFDVHDPAT GLVIAEVADG APSDATAAAD
AADRALPVWS ATPPRARADI LRRAFDLMVA QTDRLVALIC AENGKPQADA RAEVAYAADF
FRWFSEEAVR TDGSYGDSPA GDAVKIVTHR PVGPAALITP WNFPAAMATR KIAPALAAGC
TVVLKPAAET PLTALAIARL LADAGVPDGV VNVVPTTDAA GVVETLLTDP RVRKVSFTGS
TAVGRLLLAQ SAERVLNASM ELGGNAPFIV AADADLDAAV AGAMIAKFRG GGQACTAANR
FYVHADVAEE FTARFGAAIA ALRVGPAVDP ASQIGPLVSA RAAAGVRALL DQAVQEGATI
AQQADAPEGG WYVAPTLLTD VRPDASILQQ EIFGPLAPVV VWNDEDVLRR WVNDTEYGLA
AYVYSGRLQT ALRIAASIDA GMVGINRGVV SDPSAPFGGT KQSGLGREGA RDGLREFQET
QYLSVGM
//
