ID A0A135UMQ9_9PEZI Unreviewed; 4984 AA.
AC A0A135UMQ9;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Midasin {ECO:0000256|ARBA:ARBA00017143, ECO:0000256|PIRNR:PIRNR010340};
GN ORFNames=CSAL01_05628 {ECO:0000313|EMBL:KXH61694.1};
OS Colletotrichum salicis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum acutatum species complex.
OX NCBI_TaxID=1209931 {ECO:0000313|EMBL:KXH61694.1, ECO:0000313|Proteomes:UP000070121};
RN [1] {ECO:0000313|EMBL:KXH61694.1, ECO:0000313|Proteomes:UP000070121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 607.94 {ECO:0000313|EMBL:KXH61694.1,
RC ECO:0000313|Proteomes:UP000070121};
RA Baroncelli R., Thon M.R.;
RT "The genome sequence of Colletotrichum salicis CBS 607.94.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Nuclear chaperone required for maturation and nuclear export
CC of pre-60S ribosome subunits. {ECO:0000256|PIRNR:PIRNR010340}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}. Nucleus, nucleoplasm
CC {ECO:0000256|ARBA:ARBA00004642}.
CC -!- SIMILARITY: Belongs to the midasin family.
CC {ECO:0000256|ARBA:ARBA00007188, ECO:0000256|PIRNR:PIRNR010340}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXH61694.1}.
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DR EMBL; JFFI01001259; KXH61694.1; -; Genomic_DNA.
DR STRING; 1209931.A0A135UMQ9; -.
DR OrthoDB; 1221059at2759; -.
DR Proteomes; UP000070121; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 3.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 6.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR040848; AAA_lid_7.
DR InterPro; IPR011704; ATPase_dyneun-rel_AAA.
DR InterPro; IPR048617; MDN1_AAA_lid_4.
DR InterPro; IPR012099; Midasin.
DR InterPro; IPR041190; Midasin_AAA_lid_5.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR48103:SF2; MIDASIN; 1.
DR PANTHER; PTHR48103; MIDASIN-RELATED; 1.
DR Pfam; PF07728; AAA_5; 8.
DR Pfam; PF17865; AAA_lid_5; 1.
DR Pfam; PF17867; AAA_lid_7; 3.
DR Pfam; PF21108; MDN1_4th; 1.
DR PIRSF; PIRSF010340; Midasin; 1.
DR SMART; SM00382; AAA; 6.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 6.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PIRNR:PIRNR010340};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|PIRNR:PIRNR010340};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|PIRNR:PIRNR010340};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR010340};
KW Reference proteome {ECO:0000313|Proteomes:UP000070121}.
FT DOMAIN 4768..4975
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 758..781
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4107..4687
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4134..4166
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4167..4215
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4234..4254
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4255..4289
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4290..4305
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4306..4337
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4349..4407
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4437..4463
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4464..4485
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4492..4559
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4585..4599
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4611..4652
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4653..4667
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4668..4682
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4984 AA; 556362 MW; 16B03FAE2C0F1EDE CRC64;
MASIDVSTQR SALLNDATVL EHLPTEILEV IRNHTSSHLL DAVAEAALIP QLTDRIFIHF
ENVFPDICAR WLLNLDSQAV NGKNRQILAS IARILPFAPY LSEFLQHVMR DDLTKTTSDT
IQTLTLRFPK LTNSSPTQDS DLLTLLLAAW RLVCFDQRTY GTLVSPTHMQ TLFSHESRAV
RYLAIRIFTQ FLRAADSKLE ALITEHVGAT EAVLADFDGR EVDYGFLSLY EDARIKKVSA
LRRELCDASQ SNEIHSFPPQ SLTPYVACYG KTILPRPSGP VDKNSSLVLT STTTKNLESL
AGLLRNASPI LLHGLPGSGK TSLVHEVAKE FGKHSEMVTL HINEQTDAKM LIGLYSTDSK
PGTFSWRAGV LTTAVREGRW VLIEDLDRAP NEVISTLLPL IERGELLIPS RGERIKAANG
FRLFGTVRSS RGMHGRETLP NLLGMRFWQL LAVQTPTETE LQDIIVGSHP ILHKFAPGIL
AVYKRLSKPM SGNVPLSSSR GMADRQTSLR DLLRWCRRLG ATLSEAGCKT GEEPVTDTIR
MNMFKEAIDC FVAGIPDLQA KQHLIFGIAE EMHMPRELVE HHLGSYIPEL EQNDSLFKIG
RSTLRKRKDR VNKAALAKKP FASTTHAKKL LEQTAVAVNL GEPILLVGET GIGKTTVVQQ
LADTLGHKLV AINLSQQSEA GDLLGGFKPV NVRSLAVPLK EEFEDLFSAT GISTTKNQRY
LEQLGKSFAK GQWAKAAKYW REAPKMFKKI VDELARRERE QSQARDEAGQ PTKRRKTESK
LQSLMELSPR WDKFSNSLDQ FEVQLSGGAT AFAFSFVEGN IIKAARNGDW VLLDEINLAS
PDTLEAIADL LTGPVDTPSI LLSETGEIER IRAHPNFRIF GAMNPATDVG KRDLPIGIRS
RFTELYVDSP DKDVKDLITI VKTYLRNSSI KDEHAADDIA ALYMNTKRHA EEKRIVDGAN
EVPHFSLRTL TRVLTFVNYI APFYGIRRAL YEGFSMGFLT LLDRNSEQMV MPLIDLHLFG
RVSNPQSLLS QSPRQPDDGK QYVRFRNKAK DRHYWLAQGE EKTLERTDYI ITPYVERNLL
NLVRATSTRR FPILIQGPTS AGKTSMIEYL ANFTGNKFMR INNHEHTDLQ EYLGTYVSDS
SGRLRFQEGL LVQAMRQGHW IVLDELNLAP TDVLEALNRL LDDNRELLIP ETQEIVRPHE
NFMLFSTQNP PGLYGGRKVL SRAFRNRFLE LHFDDIPEDE LEYILQNRSI NTAPSDCKRI
VTVYKELSRL RQTSRLFEQK DSFATLRDLF RWALRKADTR EQIAINGFML LAERVRVDEE
RTAVREVIET VFKVKIDPDV LYTANASPIL TEVLGKSNNH GVVWTRAMRR LYVLVHAAIL
NNEPVLLVGE TGCGKTTVCQ ILGDVLGKEL HIVNAHQNTE TGDLIGSQRP VRNRGAISET
LKSDLIALLG ALGEDVSAPL DVLVQQYHGL AADKMARVDA VTQEKIALLE AKSKALFEWS
DGSLVHAMKA GQYFLLDEIS LADDSVLERL NSVLEPGRSL LLAEKGIDNS FVTAADGFQF
FATMNPGGDF GKKELSPALR NRFTEIWVPA MSEMDDMLDI VVSKLDPSFQ AFGKPVVQFA
HWFGQTFRSS SSTAFSIRDI LIWVNFINLC GPAASQFAIV HGAATVFIDS LGANPSALLA
MDPKALDSQR QKCLDKLSEL LGYDTTAVYR AQPEVVLTDD RLSIGDFGLP REAGRSTDPS
FAFNAPTTRL NAMRVMRSLQ MRKPILLEGS PGVGKTTLVA ALARVCGRPL TRINLSDQTD
LMDLFGTDMP VEGAEAGNFA WRDAPFLQAM QNGEWVLLDE MNLASQSVLE GLNACLDHRG
EVYISELDQV FKRHPDFRLF AAQNPHHQGG GRKGLPSSFV NRFIVVYADT FTAEDLLLIA
QHNFPTISTN VVSGVIQFIS RLDHQVAIEK AFGAHGSPWE FNLRDILRWL HLVATKDPLL
ATGKPDDFLD LIIRQRFRSS TDREEVNKLF AGVFAREPES HSLHHDTNAA FSQVGNALLP
RNQTSQPLKM PGIDIVPRLP EIESLMICIK QDIPCILSGP SGSGKSVLLE HVAALVGKPL
VVFPLNADID TMDLVGGFEQ SDPLREVNAT LRELFDGLQT TVLTRVPSQV PSSALVLLYL
LETYRGDTDD LPALRGAVEQ LLAEVSSESD IGALLYTAHS VLRNPLTVSN PRFEWLDGVI
VKALETGQWL VLDNANLCNA SVLDRLNSLL EPNGFLSINE HCGPNGEPRI IRPHPEFRIF
LTVDPRYGEL SRAMRNRAVE IHLSERKAQS VNSSGSRVHV ESSMQRFSSS KDISFSALSA
NDSSDVSHAT FGNLSLRDTA LMERFSHSLR RGLADPTWPG LEKYEGSLIE QLAFLDAADT
ASLRGAISQL YAKLPGSDSG LKEAQPLNPL HNASMVRVLG RNHDELPFWL SVCYEFLLEV
QRCQSAISAQ ATKAKAVKLA SLNRLQRSIL SDRIAAVAKD STVRVSKFLS RTLQVIKTFI
QSNLATAQGW KERAQVIRNM LDFWWRTLHL TTGDMFEEAR FQAHLVHGVE AVQKLLSSET
QSINRQLADR YLQTVEEDFT TGFRLTTGLS MEVMWKRIKP LPIMSEETLK TSQEIERLGI
RLDELKWKVK APVSDLARAM TTLVKADQIV RGTDLDATEL IQDLSKEIEL LESKVGSETS
EVKPFFAAEF ETLRQASLLK SHAGQYLEAV PYGANEDELT VLSNQNTIDQ IRLGSFQARE
AHSLTIGQLA SQDPATHVWN GRLATSLLSR LNSIQSTSLR SLGLLETELP AMGRSMAALA
PVLQKNQIVA LNRIVKSLLA DVFSLYSDEG DVHCETLYNR INQMFEDTKE EETLTAVTKV
MEIGFGKALQ CSDWPQHLPQ LVENHISTAM LYVVASDRLY ERPQESETDE ALMMPAFTAM
AWSEFANGAI RLYVPDKSFD PQLRPQFEKD VHDELTKQLQ HKLSSLLDFE TQFTGQQTSL
RIQLAQEEVT ALGPAPAPAQ LLYRPVRSEL NYVQTDFNNV LKMVRDQDLY NTHTKYVYLP
TGYDPAPEID LLKQNLSLMI DRLANRFYAY QDMTRPLVNL LGCLQVGLSL SAGLITLRQH
AQRSLDPEEN LMYLTPFTGG TPYHHGIKRF PNKSLEFLDY IGLVVSVEGL SKLSAGVREA
LFECVHRFYQ EWVKKLEEDR KAEEARTNLY RHKGSWEDEE EVDEEEFNEL FPTYDQEEAE
KPAIGHQKVR DVSVRLAESH RKVFLEQAAP SEALKNVCKK VGNSVAADNK DKYAVLPNMT
RRLLPLTLWS IDEQMATLTA HGVSATYNFY TEANLPEVRR LIALIDKVEA RFRDLQQVDE
IGHMQPLADV RSACDQLLQL THSEPLAKIL PKLETLHAIV YEWQHGGYAP AIYGAPALYT
SLTDTIISWR RLELSTWAKL FDMEAQKCTA DADSWFFVAY QVLIATPLSL VDSPELKDYA
VNLVRELETY FSTAIIGQFS ARLTLLRQLQ KHLELLTVDY PSLAVVSDAA INFIGFYSRF
EKIVHQTIVK GRAPFEKTMK EVVLLASWKD TNINALRESA RKSHLKLFRL VRKFRTLLGQ
PMKPILDQGI PDEDVPITQD AVAADAIDIK VDPAAIKTCD QGLPGWLAQH KRLSNASKTL
SIMANVSVQA NQSPLDATQE IISYVKELNT SIAELRKETP STLTDETKDQ VKHLKTRKRN
LFADVLKILR QMGFRYNLGT DELARQESAA VVLAGSPASI IREGSPDDAA EYYFHKVVDI
APKVKASIHE YSGDLTGAEM QRSTGFMEGM MAVLLGQHSS LSSARSAIAS LDRAIATVES
LKGTTIRHDT TRTRAGLSMN WMKPILDFGI KIVDIHGKLA SVDNQPISNI LRTTLQEVEA
LSESWSTSAS KHDKFTNGSH SDIQTRYESV AQTLNAELPT SRRDLDFILD QVRRWIHVPH
TFGRELPALD ATAQKFRHAI SSLCDAVLVA VQGYKKAMAD LPSSSDDAGW LAKTSTVRSA
GLSALHINTI VSKVEDCFSA LELVDLDKDQ MGAVASSLFS IVLPILQQYA LTCRQSLSQL
QSLQAATGHM TYNLAQTFTQ LAAKGFCSPQ EKSDEQSGDS GKMESGTGLG DGDGAEDISK
DIQPDEDLTE LAQEPNKEKD GEMEDEKDAV DMADEEMEGE MGSVNGDDEE DKSDGEGEDG
EKDDMEEEVG DVDDFDPTAV DEKMWDGDNE EEAEKDQQGE KAKGQKKDEQ MAADADVNAD
ENDAEDDNKM DQDDDEEAED EEPGQEQEDA KFEDDQVKQD QNVEENDALE MPEEMDFDFE
EDGEDAGSED DELDKLSDVE KEDAKEQHDS DIEDGEEETQ RPDEKGPEEE DEDGKEEEAP
EEDLAGEPEL DMEPKAEEEE EEAAQPEQPD ALAEPPKDNA NADANAAPSD VKGGGQDQDV
DQMDVENDFK NNAAQRDDGD AGEGSAEQQT SAGKKGQLSR SDDQAQPTDQ DQDDSAEEKS
RQDPFKKLGD ALERWHRQQN DIKDPEKQDE KEGEQKQPKD TSADLGAREF QHLEDDETAV
DAQAMGATSE DQVQPIDEAM AIDEEKEDPQ SRVMPETEDV EMEQDAADKM DTEADEALEA
QDKDNGVDKD DGRSGVKTRQ GNFDREPSPE EDEVPRDGDE EEEQAIEETS TQLSTTHISE
DDNTLPLGDF SEALQSWTSF QTKTHPLSLS LTSQLRLILT PSQSTKLSGS HRTGKRLNIK
KIIPYIASSY KRDKIWMRRA VPTKRSYQIL LAVDDSRSMG ESSSGTLALE SLVMVSRALT
MLEVGQVGVL GFGADTFLAH DLASPFASHD AGAKVLQHFH FKQDRTDIAL LIRRTIDHFR
VARLQNPSRG GGAEDLWQLA LILSDGLTPS NQHEPIRRLL REAMEERIMV VFIVMDDTGN
KKGDSVLDLK EAKFVKDERG GSRVVIERYL DTFPFQYYLI VHNLEDLPGA LAGLLRTWFA
EVNS
//
