ID A0A136IKN9_9PEZI Unreviewed; 540 AA.
AC A0A136IKN9;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 28-JUN-2023, entry version 16.
DE SubName: Full=Glycosyl hydrolase {ECO:0000313|EMBL:KXJ85485.1};
GN ORFNames=Micbo1qcDRAFT_127994 {ECO:0000313|EMBL:KXJ85485.1};
OS Microdochium bolleyi.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Microdochiaceae; Microdochium.
OX NCBI_TaxID=196109 {ECO:0000313|EMBL:KXJ85485.1, ECO:0000313|Proteomes:UP000070501};
RN [1] {ECO:0000313|Proteomes:UP000070501}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J235TASD1 {ECO:0000313|Proteomes:UP000070501};
RG DOE Joint Genome Institute;
RA David A.S., May G., Haridas S., Lim J., Wang M., Labutti K., Lipzen A.,
RA Barry K., Grigoriev I.V.;
RT "Draft genome sequence of Microdochium bolleyi, a fungal endophyte of
RT beachgrass.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 43 family.
CC {ECO:0000256|ARBA:ARBA00009865, ECO:0000256|RuleBase:RU361187}.
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DR EMBL; KQ964281; KXJ85485.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A136IKN9; -.
DR STRING; 196109.A0A136IKN9; -.
DR InParanoid; A0A136IKN9; -.
DR OrthoDB; 1891044at2759; -.
DR Proteomes; UP000070501; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd18617; GH43_XynB-like; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR041542; GH43_C2.
DR InterPro; IPR006710; Glyco_hydro_43.
DR InterPro; IPR023296; Glyco_hydro_beta-prop_sf.
DR PANTHER; PTHR42812; BETA-XYLOSIDASE; 1.
DR PANTHER; PTHR42812:SF12; BETA-XYLOSIDASE-RELATED; 1.
DR Pfam; PF17851; GH43_C2; 1.
DR Pfam; PF04616; Glyco_hydro_43; 1.
DR SUPFAM; SSF75005; Arabinanase/levansucrase/invertase; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361187};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361187};
KW Reference proteome {ECO:0000313|Proteomes:UP000070501}.
FT DOMAIN 333..539
FT /note="Beta-xylosidase C-terminal Concanavalin A-like"
FT /evidence="ECO:0000259|Pfam:PF17851"
FT ACT_SITE 17
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT ACT_SITE 197
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT SITE 135
FT /note="Important for catalytic activity, responsible for
FT pKa modulation of the active site Glu and correct
FT orientation of both the proton donor and substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-2"
SQ SEQUENCE 540 AA; 61478 MW; B2FA3EAD180EC280 CRC64;
MAEGVYNNPI LPGFNPDPSI IRVGRGYFLV TSTFEYFPGV PVYHSTDLIQ WTLIGHCLTR
RSQLDIRTPE PGGGIWAPTL RFHNGWYYMA TCAFDRYRPQ HDDRVWPRGF YVRTRDIWDS
DSWSDPVYFD QPGFDQDLFW DDDGTCYLST TYRKLDRDPA SKTKDFCIHT STIDIETGNS
TSQPVLLRES SASGVSEGSH IFRRGGYYYL FTAEGGTESG HSEWVLRSDK GPLGPYELGP
RNPLWRNTTE HEIQNTGHCD LVEDGEGRWW AVSLGVRPVR VEGEFQTSVF GRESLLMPVE
WEDDWPIFNQ GKPLTLEMRA PSLYKREPPK AWRDDFTGPD MQLGWYRKNT PLKTDFALAN
STLELHGGPY TLSSPAAPTL FLRKQCRRET LWTTRLGFVP GSARTEAGAV VYWNYFTYSS
IGIRADPGMG RVIRYRPAEG EEVVLPLRTA DGDVLLAIDC RLTSYRLGFV EVTADEEEKE
EEEEAELVNR VNWVGEVSTA AMTRDPEVGM PFTGMTLGLY AFGDMERCLT PAVFRFAQFS
//
