ID A0A136JI04_9PEZI Unreviewed; 516 AA.
AC A0A136JI04;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|EMBL:KXJ96781.1};
GN ORFNames=Micbo1qcDRAFT_229599 {ECO:0000313|EMBL:KXJ96781.1};
OS Microdochium bolleyi.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Microdochiaceae; Microdochium.
OX NCBI_TaxID=196109 {ECO:0000313|EMBL:KXJ96781.1, ECO:0000313|Proteomes:UP000070501};
RN [1] {ECO:0000313|Proteomes:UP000070501}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J235TASD1 {ECO:0000313|Proteomes:UP000070501};
RG DOE Joint Genome Institute;
RA David A.S., May G., Haridas S., Lim J., Wang M., Labutti K., Lipzen A.,
RA Barry K., Grigoriev I.V.;
RT "Draft genome sequence of Microdochium bolleyi, a fungal endophyte of
RT beachgrass.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KQ964245; KXJ96781.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A136JI04; -.
DR STRING; 196109.A0A136JI04; -.
DR InParanoid; A0A136JI04; -.
DR OrthoDB; 1820836at2759; -.
DR Proteomes; UP000070501; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR GO; GO:0000209; P:protein polyubiquitination; IEA:InterPro.
DR Gene3D; 3.30.2160.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.30.2410.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.90.1750.10; Hect, E3 ligase catalytic domains; 1.
DR InterPro; IPR044611; E3A/B/C-like.
DR InterPro; IPR000569; HECT_dom.
DR InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR PANTHER; PTHR45700:SF8; HECT DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45700; UBIQUITIN-PROTEIN LIGASE E3C; 1.
DR Pfam; PF00632; HECT; 1.
DR SMART; SM00119; HECTc; 1.
DR SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR PROSITE; PS50237; HECT; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:KXJ96781.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000070501};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW ECO:0000256|PROSITE-ProRule:PRU00104}.
FT DOMAIN 161..516
FT /note="HECT"
FT /evidence="ECO:0000259|PROSITE:PS50237"
FT ACT_SITE 484
FT /note="Glycyl thioester intermediate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00104"
SQ SEQUENCE 516 AA; 58252 MW; 0DB77EFE4F5DF741 CRC64;
MLQDWNGEAE VDGDGPFGGA LALIEAMYHK RQDLLLGDVH FRSEYFGERL DCIKMPVSWL
AFEPSHKTSH LLDYPYIFSP ASLVSYFRAI NFSQMSRSYE ESTSLRSRIG AVIAPESLVT
DSHHKNILQE LLKVPSTRYL ILDIGRRDVL RDAFDQLWRR ESRELMRPLK VHLGEDAGEE
GFDSGGVQQE FFRLAVAEAL DPDYGAFAVD DRTRMTWFQP SGLQPVWKFE LIGLLMSLAV
YNGLTLPVTF PKALYQKLLG ESVTELHHIA DGWPDLANGL TNLLEWNEKD GAVEDVFVLT
YEFSASMFGQ PVSRIMQPRN DADWPQFAAG AAPLHADNPA DAPMVTGDNR QAYVDDYIRY
LADVSVKPQF EAFARGFRTC LQPKSLSLLT PSLLQSIVEG TQEIDISELR RAARYVGWDA
SHRTVRDFWS IVKKFDDRMR RKLLEFVTAS DRVPVGGVAN IQFIIQKNGE EEADGGHLPT
AYTCYGTLLL PEYPSRDALK ERLCMALENA QGFGFA
//
