ID   A0A136KDE8_9BACT        Unreviewed;       473 AA.
AC   A0A136KDE8;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   22-FEB-2023, entry version 14.
DE   SubName: Full=UDP-N-acetyl-alpha-D-glucosamine C6 dehydratase {ECO:0000313|EMBL:KXK07445.1};
DE            EC=4.2.1.135 {ECO:0000313|EMBL:KXK07445.1};
GN   Name=pglF {ECO:0000313|EMBL:KXK07445.1};
GN   ORFNames=UZ21_OP11001001069 {ECO:0000313|EMBL:KXK07445.1};
OS   Microgenomates bacterium OLB22.
OC   Bacteria; Candidatus Microgenomates.
OX   NCBI_TaxID=1617428 {ECO:0000313|EMBL:KXK07445.1, ECO:0000313|Proteomes:UP000070562};
RN   [1] {ECO:0000313|EMBL:KXK07445.1, ECO:0000313|Proteomes:UP000070562}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OLB22 {ECO:0000313|EMBL:KXK07445.1};
RA   Speth D.R., In T Zandt M., Guerrero Cruz S., Dutilh B.E., Jetten M.S.;
RT   "Genome based microbial ecology of anammox granules in a full-scale
RT   wastewater treatment system.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC       {ECO:0000256|ARBA:ARBA00007430}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KXK07445.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LLEV01000020; KXK07445.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A136KDE8; -.
DR   STRING; 1617428.UZ21_OP11001001069; -.
DR   PATRIC; fig|1617428.3.peg.1105; -.
DR   Proteomes; UP000070562; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003869; Polysac_CapD-like.
DR   PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR   PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR   Pfam; PF13727; CoA_binding_3; 1.
DR   Pfam; PF02719; Polysacc_synt_2; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000313|EMBL:KXK07445.1}.
FT   DOMAIN          148..429
FT                   /note="Polysaccharide biosynthesis protein CapD-like"
FT                   /evidence="ECO:0000259|Pfam:PF02719"
SQ   SEQUENCE   473 AA;  53310 MW;  CF06BDB952E3A71C CRC64;
     MSPKSIPVLI VGAGNAGRQL LREFKKSNEL NYCIVGFLDD DPKKKNKAIR GIPVIGTLED
     LEMQVKKNKI KIVFIAFPSV HGGVIRALAG RCKKIGVECR IIPKFLEIIQ NKVRLSFVRP
     VTIDDLVGRP IIKKDQIKFL SLLKDKKVLV TGAAGSIGSE LVRQINEFSP RKIICGDQWE
     TGLFDLEHEL KGKKEVEKDF IILNIQDRQK MDWVFKKHKP DYVFHAAAYK HVPLMDLHPE
     EAVKNNIIGT KNVAYLAGKY GAEKFTFIST DKAVNPSSVM GATKSFCEAL LQYYEKKFKT
     VYCSVRFGNV LGSYGSVVPL FQKQIAKGGP VTVTHPDMKR FFMTIPEAVQ LVLHASRIGK
     GGEIFLLEMG EQMKILDLAN TMIRLSGLEP GKDIQIKITG IRPGEKLYEE LFAEQEELSK
     TDHDLIYALK NVSHQVSDTL LSTYARLKAL AKKNDRENLI KELRTFYTNL QKS
//