ID A0A137P5S7_CONC2 Unreviewed; 695 AA.
AC A0A137P5S7;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Alpha/beta-hydrolase {ECO:0000313|EMBL:KXN70281.1};
GN ORFNames=CONCODRAFT_70811 {ECO:0000313|EMBL:KXN70281.1};
OS Conidiobolus coronatus (strain ATCC 28846 / CBS 209.66 / NRRL 28638)
OS (Delacroixia coronata).
OC Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota;
OC Entomophthoromycotina; Entomophthoromycetes; Entomophthorales;
OC Ancylistaceae; Conidiobolus.
OX NCBI_TaxID=796925 {ECO:0000313|EMBL:KXN70281.1, ECO:0000313|Proteomes:UP000070444};
RN [1] {ECO:0000313|EMBL:KXN70281.1, ECO:0000313|Proteomes:UP000070444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 28638 {ECO:0000313|EMBL:KXN70281.1,
RC ECO:0000313|Proteomes:UP000070444};
RX PubMed=25977457; DOI=10.1093/gbe/evv090;
RA Chang Y., Wang S., Sekimoto S., Aerts A.L., Choi C., Clum A., LaButti K.M.,
RA Lindquist E.A., Yee Ngan C., Ohm R.A., Salamov A.A., Grigoriev I.V.,
RA Spatafora J.W., Berbee M.L.;
RT "Phylogenomic Analyses Indicate that Early Fungi Evolved Digesting Cell
RT Walls of Algal Ancestors of Land Plants.";
RL Genome Biol. Evol. 7:1590-1601(2015).
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DR EMBL; KQ964507; KXN70281.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A137P5S7; -.
DR STRING; 796925.A0A137P5S7; -.
DR EnsemblFungi; KXN70281; KXN70281; CONCODRAFT_70811.
DR OMA; WVQMRII; -.
DR OrthoDB; 37251at2759; -.
DR Proteomes; UP000070444; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 2.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR013094; AB_hydrolase_3.
DR InterPro; IPR033140; Lipase_GDXG_put_SER_AS.
DR PANTHER; PTHR23025:SF3; HORMONE-SENSITIVE LIPASE; 1.
DR PANTHER; PTHR23025; TRIACYLGLYCEROL LIPASE; 1.
DR Pfam; PF07859; Abhydrolase_3; 2.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS01174; LIPASE_GDXG_SER; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:KXN70281.1};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000070444};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 16..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 56..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 114..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 215..376
FT /note="Alpha/beta hydrolase fold-3"
FT /evidence="ECO:0000259|Pfam:PF07859"
FT DOMAIN 436..530
FT /note="Alpha/beta hydrolase fold-3"
FT /evidence="ECO:0000259|Pfam:PF07859"
FT REGION 574..594
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 308
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10038"
SQ SEQUENCE 695 AA; 78094 MW; 447AC18757F3E5EA CRC64;
MLDQLLGKPS HNIKRVQVLV ALYLSSIVFW GKGNYLNSKI FDKINDKLKK YSPSQLIFLT
LSVLYCLKHS LLFSGLYPPN SMAHMYSRNF YRATYIYTAL CAGSLAANPI KPKFLRDTVA
LFFIFYYLVF PNHAESRMRA TGRVITAQAM RVAWESEKNI YLQCISYWTS PKVELIKKVW
IPRGSDSPHG TKPVEALIVF NGTKEELRKA KGLIFHIPGG GFVCMPPERH LAYLKKWAQD
TKYPVISFNY HKAPEHPYPY ALNELFDAYR TICSTHGRCL GIDSLPIKPL IKNGVKFNEI
AISFAGDSAG GNLCASLMLL ILEAGQNLGD NFVVPRPRGI VFIYPALEFN MGVWMNNDEL
KLFRQQSVKS LASLWETKSH CNHESPLATY DDTKSWGGVF SKASIKDQVQ AHLPKKPDLV
KVPSERGLHK IDTTKYPWVR NKANPLAMSS KITYFDDRVL SAEIFRAVAI WYVGPNNTGN
FQSDYYVSPL LAPDHLLAQF PKTYFICGER DPLVDDTIIM SGKIRNAKRK LSRSNSRRKA
ASFDPDLGKL TPLSNSVSLD ASIDGFIIGN DNSNANSNVN SDHEDDSEYD SDLSDSASIM
STSTVIQNPK MSLASRFANR VKSYVSLFQQ PPAVPTESFD HTTTVSVEDV HVKLITGISH
GFMNFEAFLP EAKAAIKLTG TWLDDILHDN NEDED
//
