ID A0A137QCA2_9AGAR Unreviewed; 495 AA.
AC A0A137QCA2;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=2-methylacyl-CoA dehydrogenase, mitochondrial {ECO:0000313|EMBL:KXN84883.1};
DE Flags: Fragment;
GN ORFNames=AN958_12013 {ECO:0000313|EMBL:KXN84883.1};
OS Leucoagaricus sp. SymC.cos.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Agaricaceae; Leucoagaricus.
OX NCBI_TaxID=1714833 {ECO:0000313|EMBL:KXN84883.1, ECO:0000313|Proteomes:UP000070249};
RN [1] {ECO:0000313|EMBL:KXN84883.1, ECO:0000313|Proteomes:UP000070249}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SymC.cos {ECO:0000313|EMBL:KXN84883.1,
RC ECO:0000313|Proteomes:UP000070249};
RA Hu H.;
RT "Leucoagaricus sp. SymC.cos WGS genome.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the acyl-CoA dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009347}.
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DR EMBL; KQ962566; KXN84883.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A137QCA2; -.
DR STRING; 1714833.A0A137QCA2; -.
DR OrthoDB; 294001at2759; -.
DR Proteomes; UP000070249; Unassembled WGS sequence.
DR GO; GO:0003995; F:acyl-CoA dehydrogenase activity; IEA:InterPro.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR Gene3D; 1.10.540.10; Acyl-CoA dehydrogenase/oxidase, N-terminal domain; 1.
DR Gene3D; 2.40.110.10; Butyryl-CoA Dehydrogenase, subunit A, domain 2; 1.
DR Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 1.
DR Gene3D; 3.10.120.10; Cytochrome b5-like heme/steroid binding domain; 1.
DR InterPro; IPR006089; Acyl-CoA_DH_CS.
DR InterPro; IPR006091; Acyl-CoA_Oxase/DH_mid-dom.
DR InterPro; IPR046373; Acyl-CoA_Oxase/DH_mid-dom_sf.
DR InterPro; IPR036250; AcylCo_DH-like_C.
DR InterPro; IPR009075; AcylCo_DH/oxidase_C.
DR InterPro; IPR013786; AcylCoA_DH/ox_N.
DR InterPro; IPR037069; AcylCoA_DH/ox_N_sf.
DR InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR InterPro; IPR001199; Cyt_B5-like_heme/steroid-bd.
DR InterPro; IPR036400; Cyt_B5-like_heme/steroid_sf.
DR PANTHER; PTHR48083:SF28; ACYL-COA DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10880); 1.
DR PANTHER; PTHR48083; MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF00441; Acyl-CoA_dh_1; 1.
DR Pfam; PF02770; Acyl-CoA_dh_M; 1.
DR Pfam; PF02771; Acyl-CoA_dh_N; 1.
DR Pfam; PF00173; Cyt-b5; 1.
DR SMART; SM01117; Cyt-b5; 1.
DR SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 1.
DR SUPFAM; SSF55856; Cytochrome b5-like heme/steroid binding domain; 1.
DR PROSITE; PS00072; ACYL_COA_DH_1; 1.
DR PROSITE; PS50255; CYTOCHROME_B5_2; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Reference proteome {ECO:0000313|Proteomes:UP000070249}.
FT DOMAIN 1..62
FT /note="Cytochrome b5 heme-binding"
FT /evidence="ECO:0000259|PROSITE:PS50255"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KXN84883.1"
SQ SEQUENCE 495 AA; 55498 MW; E004BFE8B7B18825 CRC64;
WIIIDSKVYD LSRFANMHPG GLAVLLDDDI AGRDATEAFF SLHRYEVLQK PQYARLAIGN
LVDTSQQIFP KAVGGLSNVP YAEPTWLTSG YYSPYYKDHH RKFQAAFRKF VEEVIIPDAQ
AHEEDGKPPS THVFQEMAKL NIIAMRVGRG PHLKGRTLMG GIVEPEEFDC FHELIMGQEL
ARIHARGYSD GLGGGIFIGL PPIINFARPE LRDRVTKEVL DGRKFICLAV TEAFAGSDVA
GLRCFAKRVE NGWIVTGTKK WITNGTFADY FVVGCRTEKG GLVVLFVERG EGVETKLIKT
SYSTTAGTAY ITFERVFVPY EHTIGPDNDG LRVILSNFNH ERWGMTVTCI SAQRAITEEC
LKWVNQRKVF GKPLHSQGVI RSKLAGMIVR VESAQSWLEN ITYQMNHMNY KDQSRYLAGS
IGLLKKFATE NAQETARDAV QIFGGRGITR TGMGRFIEHY HRTVPFDAAP GGAEYVMGDL
GVRQALKYMP RDVRL
//
