ID A0A139CSU1_9EURY Unreviewed; 785 AA.
AC A0A139CSU1;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=AWU59_612 {ECO:0000313|EMBL:KXS44334.1};
OS Methanolobus sp. T82-4.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanolobus.
OX NCBI_TaxID=1794908 {ECO:0000313|EMBL:KXS44334.1, ECO:0000313|Proteomes:UP000074030};
RN [1] {ECO:0000313|EMBL:KXS44334.1, ECO:0000313|Proteomes:UP000074030}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T82-4 {ECO:0000313|EMBL:KXS44334.1};
RA Wolfe R., Daly R., Wrighton K.;
RT "Methanolobus T82 Annotated.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXS44334.1}.
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DR EMBL; LSRV01000011; KXS44334.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A139CSU1; -.
DR STRING; 1794908.AWU59_612; -.
DR Proteomes; UP000074030; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR43711:SF1; HISTIDINE KINASE 1; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF13426; PAS_9; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 205..257
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 258..328
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 338..390
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 551..770
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 785 AA; 89939 MW; 827FFC52C60FA8A2 CRC64;
MTKTVILACC EQAHEKTALM LEKMGFSVCR LDCSQDNCDR ELSNTSADLL FCYTEKVNEE
MVDHCLAHSR DKQIPVIFII SRVKGFPEKI QSFDHAWFIK EPFDEDELSF TIERSFHVLK
KENDIKLNEA NHQRLQLALE TAKLELWEWD FKENRVVRET IGGANSIIPS DLKCGGFDTF
HRFIHPDDRD MFREKMKACW EGKQIHIEFR SVPIDGSVHW YSLNLKPLFD ESGKPEKMIG
ISRDITQRKD TEIALRESEE RFRLIAESAK DVIWLLDRNA KLLYISPSVE KLRGYTPEEL
MDTPFDKILM PDSYKELMGV FETFFRHFRK GVIPDVPRIF EVQQPCKDGS TVWTEMHITP
VLDEEGNFRF FLGISRNIDE RKRNEQELEK QRKLLDSIFN LAPIPLILED SNRNIENVNN
SCMEVTRKNK EHMIGQKAGK VFSCINVHRG NVCGTSEECN KCIFKNAAEE TLRRGKGISK
REGKTTIVLP NGSEVSRNVL VSTSYIDTGE EPKVIFGVND ITDLKKFEHS IIESRIQAEE
ANRAKSEFLA NMSHELQTPL NAIMGYSEIL QDSHFGHLNE KQKKFAEHIN TSGRHLLELI
NSILDISKVE SGKMELHLHD FRVIDTIRNV KNVIVPLARK KDIELKFSVE PESLSLHADE
IKFKQILYNL LSNAVKFTPD NGLVEVKVHK ESDMAEISVT DTGIGISAED QEKLFTPFHQ
IDSSMSRKYQ GTGLGLALVK RFVELHGGNI TVESEPGIGS TFIFTIPLIS QNTYSGDIEM
ELSAN
//
