ID   A0A139N9D9_9STRE        Unreviewed;       595 AA.
AC   A0A139N9D9;
DT   11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT   11-MAY-2016, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Beta-galactosidase 3 {ECO:0000313|EMBL:KXT72669.1};
GN   ORFNames=STRDD10_01800 {ECO:0000313|EMBL:KXT72669.1};
OS   Streptococcus sp. DD10.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1777878 {ECO:0000313|EMBL:KXT72669.1, ECO:0000313|Proteomes:UP000072050};
RN   [1] {ECO:0000313|EMBL:KXT72669.1, ECO:0000313|Proteomes:UP000072050}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DD10 {ECO:0000313|EMBL:KXT72669.1,
RC   ECO:0000313|Proteomes:UP000072050};
RA   Denapaite D., Rieger M., Koendgen S., Brueckner R., Ochigava I.,
RA   Kappeler P., Maetz-Rensing K., Leendertz F., Hakenbeck R.;
RT   "Highly variable Streptococcus oralis are common among viridans
RT   streptococci isolated from primates.";
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC       {ECO:0000256|ARBA:ARBA00009809, ECO:0000256|RuleBase:RU003679}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KXT72669.1}.
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DR   EMBL; LQRE01000141; KXT72669.1; -; Genomic_DNA.
DR   RefSeq; WP_067195161.1; NZ_KQ969164.1.
DR   AlphaFoldDB; A0A139N9D9; -.
DR   STRING; 1777878.STRDD10_01800; -.
DR   PATRIC; fig|1777878.3.peg.1974; -.
DR   OrthoDB; 9813184at2; -.
DR   Proteomes; UP000072050; Unassembled WGS sequence.
DR   GO; GO:0004565; F:beta-galactosidase activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR026283; B-gal_1-like.
DR   InterPro; IPR048912; BetaGal1-like_ABD1.
DR   InterPro; IPR048913; BetaGal_gal-bd.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR   InterPro; IPR001944; Glycoside_Hdrlase_35.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR23421:SF165; BETA-GALACTOSIDASE; 1.
DR   PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR   Pfam; PF21317; BetaGal_ABD_1; 1.
DR   Pfam; PF21467; BetaGal_gal-bd; 1.
DR   Pfam; PF01301; Glyco_hydro_35; 1.
DR   PIRSF; PIRSF006336; B-gal; 1.
DR   PRINTS; PR00742; GLHYDRLASE35.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000072050}.
FT   DOMAIN          10..328
FT                   /note="Glycoside hydrolase 35 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF01301"
FT   DOMAIN          373..488
FT                   /note="Beta-galactosidase 1-like first all-beta"
FT                   /evidence="ECO:0000259|Pfam:PF21317"
FT   DOMAIN          506..564
FT                   /note="Beta-galactosidase galactose-binding"
FT                   /evidence="ECO:0000259|Pfam:PF21467"
FT   ACT_SITE        157
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
FT   ACT_SITE        239
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
SQ   SEQUENCE   595 AA;  68754 MW;  E1D0FD5B36BCE0F2 CRC64;
     MARFEIKEDF YLDQQPFKIL SGAIHYFRVH PEDWYHSLYN LKALGFNTVE TYVPWNLHEP
     KEGKFNFKGI ADVERFLKIA QDLGLYAIVR PSPYICAEWE FGGLPAWLLE KKEMRIRSSD
     SQFLACIEHY YEQLLPRLAP FELENGGNIL MMQVENEYGS YGEDKTYLRA VKRLMRRAGI
     RCPLFTSDGP WRATLRAGSM IEDDIFTTGN FGSKADYNFS QMQEFFDEHG KKWPLMCMEF
     WDGWFNRWKE PIIRRDGEEL AEAIHEVLKR GSINLYMFHG GTNFGFMNGC SARGTTDLPQ
     VTSYDYDALL NEQGNPTAKY FAVKQMIATH YPDYPQLEPL VKESIETSAC LVDKVSLFET
     VDSIAKPIES LYPLSATELG QGYGYTLYQV EDTWDADEER LRVIDARDRM QLYLNGHLQA
     TQYQTEIGED IFCKAKKKAL AHIDILIENM GRVNYGHKLL ADTQTKGIRQ GVCKDLHFML
     GWKQYALELD TLDGLDFSKE WKEGQPAFYR YHLQLDRVKD SFIDLSGFGK GVVFVNGVNI
     GRFWDVGPTL SLYVPHGLLK EGENEMIVFE TEGRYQETLP LVSQPIFKII KGENL
//