ID A0A139TPS5_9BACT Unreviewed; 687 AA.
AC A0A139TPS5;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Glycosyl hydrolase family 2, sugar binding domain protein {ECO:0000313|EMBL:KXU53589.1};
GN ORFNames=HMPREF3039_02312 {ECO:0000313|EMBL:KXU53589.1};
OS Akkermansia sp. KLE1798.
OC Bacteria; Verrucomicrobiota; Verrucomicrobiae; Verrucomicrobiales;
OC Akkermansiaceae; Akkermansia.
OX NCBI_TaxID=1574265 {ECO:0000313|EMBL:KXU53589.1, ECO:0000313|Proteomes:UP000070454};
RN [1] {ECO:0000313|EMBL:KXU53589.1, ECO:0000313|Proteomes:UP000070454}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KLE1798 {ECO:0000313|EMBL:KXU53589.1,
RC ECO:0000313|Proteomes:UP000070454};
RA Wen L., He K., Yang H.;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXU53589.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LTZM01000048; KXU53589.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A139TPS5; -.
DR PATRIC; fig|1574265.3.peg.2248; -.
DR Proteomes; UP000070454; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR032311; DUF4982.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR42732:SF1; BETA-MANNOSIDASE; 1.
DR Pfam; PF16355; DUF4982; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:KXU53589.1}.
FT DOMAIN 22..155
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 171..275
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 283..581
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
FT DOMAIN 599..656
FT /note="DUF4982"
FT /evidence="ECO:0000259|Pfam:PF16355"
FT REGION 665..687
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 687 AA; 75998 MW; 5400F446E5BD81B7 CRC64;
MADAREVYPL TGSWDYRFDG GPSEKVTVPH TWNASDAADG VKGKRGDAKS VDSGVYKRGA
AVYTRTLPVT PKPGKRYFIR GEGASIVSEV SVNGKPAGRH EGAFTAFCHE ITPLLKKGGN
TVSVMVDNTQ RDHIAPQRGD FSMFGGLYRP IELIETDQVC IDPLFYASPG VFITTRSLDK
SRAEVEVKTL LNAAEAKGDV AVAVEILDKQ GKKVAGKTVK ASAEEKKSLE VPVVLTISNP
VPWNATKNPY LYQVKVSIRT ADGQTDEMVQ PLGLRTVSID PQQGFVLNGK TMQIKGVSRH
QDRKGKGWAL SPEDEAQDIK MIADMGADGL RTAHYPASTN IYDLCDKTGL VVWSEVSNVN
LVRDTPEFRE NNRLQAREMI YQHWNHPSIC MWGIFNEIGH QAEASTKGVD MEAELIELNK
FVKETDPTRM TVGASNQPGR KKLNNIPDHI AFNSYPGWYG GGPETMKGNL NGFIRDHASK
GVAISEYGHG ASTGMHENPP KRPSPTGFWH PEEWQTHAHE INYKCIKERP EVWGSFVWNM
FDFGSAGRFE GENPGINDKG LVTYDRKTPK DAYFFYRANW SPKPTVYITS RRFAERTEKT
VPVKVYSNAS SVKLSVNGKA VGSAKPDELR RAVWPEVALK PGVNTITATA TIGGKTYTDS
CKWTLKPGKE GEKGSERYQD PSIKKYK
//
