ID A0A139WGR3_TRICA Unreviewed; 2789 AA.
AC A0A139WGR3;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Apolipophorins-like protein {ECO:0000313|EMBL:KYB26997.1};
GN Name=AUGUSTUS-3.0.2_34740 {ECO:0000313|EMBL:KYB26997.1};
GN ORFNames=TcasGA2_TC034740 {ECO:0000313|EMBL:KYB26997.1};
OS Tribolium castaneum (Red flour beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Tenebrionidae; Tenebrionidae incertae sedis; Tribolium.
OX NCBI_TaxID=7070 {ECO:0000313|EMBL:KYB26997.1, ECO:0000313|Proteomes:UP000007266};
RN [1] {ECO:0000313|EMBL:KYB26997.1, ECO:0000313|Proteomes:UP000007266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Georgia GA2 {ECO:0000313|EMBL:KYB26997.1,
RC ECO:0000313|Proteomes:UP000007266};
RX PubMed=18362917; DOI=10.1038/nature06784;
RG Tribolium Genome Sequencing Consortium;
RA Richards S., Gibbs R.A., Weinstock G.M., Brown S.J., Denell R.,
RA Beeman R.W., Gibbs R., Beeman R.W., Brown S.J., Bucher G., Friedrich M.,
RA Grimmelikhuijzen C.J., Klingler M., Lorenzen M., Richards S., Roth S.,
RA Schroder R., Tautz D., Zdobnov E.M., Muzny D., Gibbs R.A., Weinstock G.M.,
RA Attaway T., Bell S., Buhay C.J., Chandrabose M.N., Chavez D.,
RA Clerk-Blankenburg K.P., Cree A., Dao M., Davis C., Chacko J., Dinh H.,
RA Dugan-Rocha S., Fowler G., Garner T.T., Garnes J., Gnirke A., Hawes A.,
RA Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N., Joshi V.,
RA Khan Z.M., Jackson L., Kovar C., Kowis A., Lee S., Lewis L.R., Margolis J.,
RA Morgan M., Nazareth L.V., Nguyen N., Okwuonu G., Parker D., Richards S.,
RA Ruiz S.J., Santibanez J., Savard J., Scherer S.E., Schneider B.,
RA Sodergren E., Tautz D., Vattahil S., Villasana D., White C.S., Wright R.,
RA Park Y., Beeman R.W., Lord J., Oppert B., Lorenzen M., Brown S., Wang L.,
RA Savard J., Tautz D., Richards S., Weinstock G., Gibbs R.A., Liu Y.,
RA Worley K., Weinstock G., Elsik C.G., Reese J.T., Elhaik E., Landan G.,
RA Graur D., Arensburger P., Atkinson P., Beeman R.W., Beidler J., Brown S.J.,
RA Demuth J.P., Drury D.W., Du Y.Z., Fujiwara H., Lorenzen M., Maselli V.,
RA Osanai M., Park Y., Robertson H.M., Tu Z., Wang J.J., Wang S., Richards S.,
RA Song H., Zhang L., Sodergren E., Werner D., Stanke M., Morgenstern B.,
RA Solovyev V., Kosarev P., Brown G., Chen H.C., Ermolaeva O., Hlavina W.,
RA Kapustin Y., Kiryutin B., Kitts P., Maglott D., Pruitt K., Sapojnikov V.,
RA Souvorov A., Mackey A.J., Waterhouse R.M., Wyder S., Zdobnov E.M.,
RA Zdobnov E.M., Wyder S., Kriventseva E.V., Kadowaki T., Bork P., Aranda M.,
RA Bao R., Beermann A., Berns N., Bolognesi R., Bonneton F., Bopp D.,
RA Brown S.J., Bucher G., Butts T., Chaumot A., Denell R.E., Ferrier D.E.,
RA Friedrich M., Gordon C.M., Jindra M., Klingler M., Lan Q., Lattorff H.M.,
RA Laudet V., von Levetsow C., Liu Z., Lutz R., Lynch J.A., da Fonseca R.N.,
RA Posnien N., Reuter R., Roth S., Savard J., Schinko J.B., Schmitt C.,
RA Schoppmeier M., Schroder R., Shippy T.D., Simonnet F., Marques-Souza H.,
RA Tautz D., Tomoyasu Y., Trauner J., Van der Zee M., Vervoort M.,
RA Wittkopp N., Wimmer E.A., Yang X., Jones A.K., Sattelle D.B., Ebert P.R.,
RA Nelson D., Scott J.G., Beeman R.W., Muthukrishnan S., Kramer K.J.,
RA Arakane Y., Beeman R.W., Zhu Q., Hogenkamp D., Dixit R., Oppert B.,
RA Jiang H., Zou Z., Marshall J., Elpidina E., Vinokurov K., Oppert C.,
RA Zou Z., Evans J., Lu Z., Zhao P., Sumathipala N., Altincicek B.,
RA Vilcinskas A., Williams M., Hultmark D., Hetru C., Jiang H.,
RA Grimmelikhuijzen C.J., Hauser F., Cazzamali G., Williamson M., Park Y.,
RA Li B., Tanaka Y., Predel R., Neupert S., Schachtner J., Verleyen P.,
RA Raible F., Bork P., Friedrich M., Walden K.K., Robertson H.M., Angeli S.,
RA Foret S., Bucher G., Schuetz S., Maleszka R., Wimmer E.A., Beeman R.W.,
RA Lorenzen M., Tomoyasu Y., Miller S.C., Grossmann D., Bucher G.;
RT "The genome of the model beetle and pest Tribolium castaneum.";
RL Nature 452:949-955(2008).
RN [2] {ECO:0000313|EMBL:KYB26997.1, ECO:0000313|Proteomes:UP000007266}
RP GENOME REANNOTATION.
RC STRAIN=Georgia GA2 {ECO:0000313|EMBL:KYB26997.1,
RC ECO:0000313|Proteomes:UP000007266};
RX PubMed=19820115; DOI=10.1093/nar/gkp807;
RA Kim H.S., Murphy T., Xia J., Caragea D., Park Y., Beeman R.W.,
RA Lorenzen M.D., Butcher S., Manak J.R., Brown S.J.;
RT "BeetleBase in 2010: revisions to provide comprehensive genomic information
RT for Tribolium castaneum.";
RL Nucleic Acids Res. 38:D437-D442(2010).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00557}.
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DR EMBL; KQ971346; KYB26997.1; -; Genomic_DNA.
DR RefSeq; XP_015836415.1; XM_015980929.1.
DR STRING; 7070.A0A139WGR3; -.
DR EnsemblMetazoa; TC034740_001; TC034740_001; TC034740.
DR GeneID; 663181; -.
DR KEGG; tca:663181; -.
DR eggNOG; KOG4338; Eukaryota.
DR InParanoid; A0A139WGR3; -.
DR OMA; QGFKYQY; -.
DR OrthoDB; 3138458at2759; -.
DR Proteomes; UP000007266; Linkage group 6.
DR GO; GO:0005319; F:lipid transporter activity; IBA:GO_Central.
DR Gene3D; 2.20.80.10; Lipovitellin-phosvitin complex, chain A, domain 4; 1.
DR Gene3D; 2.20.50.20; Lipovitellin. Chain A, domain 3; 1.
DR Gene3D; 1.25.10.20; Vitellinogen, superhelical; 1.
DR InterPro; IPR015819; Lipid_transp_b-sht_shell.
DR InterPro; IPR009454; Lipid_transpt_open_b-sht.
DR InterPro; IPR011030; Lipovitellin_superhlx_dom.
DR InterPro; IPR015816; Vitellinogen_b-sht_N.
DR InterPro; IPR015255; Vitellinogen_open_b-sht.
DR InterPro; IPR015817; Vitellinogen_open_b-sht_sub1.
DR InterPro; IPR001747; Vitellogenin_N.
DR PANTHER; PTHR23345:SF15; VITELLOGENIN-1-RELATED; 1.
DR PANTHER; PTHR23345; VITELLOGENIN-RELATED; 1.
DR Pfam; PF06448; DUF1081; 1.
DR Pfam; PF09172; Vit_open_b-sht; 1.
DR Pfam; PF01347; Vitellogenin_N; 1.
DR SMART; SM01169; DUF1943; 1.
DR SMART; SM00638; LPD_N; 1.
DR SUPFAM; SSF48431; Lipovitellin-phosvitin complex, superhelical domain; 1.
DR PROSITE; PS51211; VITELLOGENIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000007266};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..2789
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007299931"
FT DOMAIN 41..644
FT /note="Vitellogenin"
FT /evidence="ECO:0000259|PROSITE:PS51211"
FT COILED 699..726
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 2789 AA; 310432 MW; 582BC7294B9A680C CRC64;
MARRSPSRVG LALALICLIS HGQAEETCRT GCRGAAQTFK YKEGTTYKYN YDSKIEVSLS
GADGQKSVTE VKATVLLTQQ PQCNQILRLQ NVQIVGNDGK KHTNLPDTDK PISINYHDGH
LEDSICITPG DSQNSLNLKR AIASILQANL KSGHETDVFG LCPTEVTHHK EGNMVVVQKA
RNLNRCAFRE NIKQDFIATA FNLNSEIKSS PILNGDYDAT LRIKNGILDQ ATVHEHYLYV
PFSVGTNGAK AAIETNLKYV GTAKDNSQVK GGHPRSIIFE DPHPVHSPHT NVNSILNAVK
QTAKTIDVVV GEHTAKEFTN LVKILRVSKK DDLLAVYNQV RAGVGFPDKV AGKKIFLDAL
LRAGNGDNIE VAIELLKNKE LTPVEQNLVF LGLSTVRHPT ENSLATAAAL LDQPNLPRNA
YLGVGNLAGR FCRQHRCEHA EGLKKLTQKL VQKLGKQPTN RHDENDLIYV LKALGNFHHL
CDEVLEKVTG LAQNRKNSNR VRVTALETYL ADPCKDKLRD SAIGILKDVQ QDSEVRIKAY
LALAQCPNSK VASAVKAVLE KEPSYQVGGF IQTHIRNIRA SANPDKELAK QHLGQITVPK
KYPFDLRKYS ANGEFSYTFD TLGIANSIES NIIYSQTSFL PRSTSLNLTA EIFGHTLNFL
DIQTRQENLD RLVEHYLGPK GLLRSKTLQQ LWDGTGPRVK KLTEELDSRL RELLRARRDL
SKAEIESVGK QVEIKTNELN RDLDLDLSVK AFGSEVLFLN LNDDVRKYTP EAVIDQILAG
FKQGLDRIKH FDETLRSNLL FLDAELSYPT SSGFPLRLGV EGSANLQVKT AGSFDMKQGH
KVKFTLIPSA NVEVSGRLTV DTLVLESGLK IISTLHTATG GDLTYEALKN GEDIKFSFPV
EKQNILSASH DIVFHNREWG SPEVNTPLKF AQNKDFSICL DQLSPFIGLT FCGEFNGPNL
QGQKVPILPF PLSGDARVEV TVEKEDLSMY HFRNEYFLQE SGKTGLEVVL EALGKSGQKK
VALTLEAFLQ PERYFKAALT SPVTSAVLEG RITLTDSERS LSLRFAQDKN EYFGKIGVAV
QGSAAKAIYK PLVQYKTPQD GALQVPPYRV DGQVIVENNG PATTYTLDNV KLIIPNQKTI
TFNGKFGHEP ETVFADLTVS DGNSNAAFKG KLRVNANLIK YNAELKNSLN PSANIHLKGE
LAKSAEELKN FFQVAHGGDF SDKNSILTLE NSLKHRNKGP QDFLLDTKNK LSYPGLGANL
EFEFQLKPKA VEYDLDVQYG STKFGSELEY EHNSKREGTE FKLDFGIWGL NNRVNIKGKR
TINGEQSHIE NSYEINGKRT EINGKIRHHL RPQDVDFGAD LEIKVPQHNT PFKVLGEFKL
NPNEIDASNK ITSGGTVYLD AFLKANKAGN ANGSIKVNLK GQLLVSGQVK ANKGSGTGDL
EVELPSQGRK SKIDTTFTVH EPTYNIVVNI YPVFDKDKSK KITLSTQTSL KPHQLDSKNF
IDFFGNKVEG NVKGSQQGDL SNGKITGEAE LTLPNNCYFA GKIDREMKTV EQVLNGNAIA
SIEYRPNKNQ PGNKFTIKGH AKDTNPSEKI FDLNYQITAE SAKGKNLNFD LMVKRVPQGE
RFNIQMHNKI YGSELPSPIE TTLKGTCDGF TGSFEGASTY APFGKIAIRG KHDFSGSGKP
VSGELDLDVT TTSQHLKTMK FSIGGSLHKS DNVDVKGQVK FFGENAKGVF AEFDSNGEVK
VSDREARARG TIKTGQLDPI SVSVGMSRLE DKEVKGDLGF EFGKGQKAKG DFTLIRLQPH
EYKLDLKFDT PAEKFKSNRI QVHTKSNDAR THHQSEVILT SDGKTWTANT DLVLSEIAPS
VDIKVKCPEG KLRQFLAKVT KMSDRQLGAQ LKIVNQKENF LLEGTVDANV ENIDDFHVKI
TANAPTLKID KYVIEAQNKP AKTGRRIQVT AKSGNKNILA GSTSYTAREE HGKVIIEGSG
SFKLHDETKS ANFKYIRQNL VQAKNGETGI EISFDASLGN KAIDAELKIT DKQFRILNSY
CEEKKQCAHV EVDVKTTVDD VKAFNQEIEI AIDLRKLGLS HEFGLKAVTT RKEYVLDHTV
DMHFQSQENS KYQYSLYVHP NQAGVSLTTP KRIIALESKI NVPSKFLQDG GSVSGEVFFY
TDKKNQPNKK SGLISYLNLN PKGPTLDGEI KFTNPALKRP LLISIKSKYV PMSLESVVTF
DVFAQPDQKL VIKHTEKWSD PKDYKKMEAK EVVEIKSTGL HIDIHYEEYA FASVEDHHYK
AEVKLRYSGP GSKHESGALY EVTPKNLEAG IKLFNHQLFH LTSKYQLSQN HQVFDSELGC
YGHRPLVSHL EVKNLNTLKY SIACKDKPND KLLVNCGFKP GEIADVRAEI IKGGQTHELG
HATVKLDDAN FLKSDYKVQA KNIEELLFKP IKDGIQREGD ELAKLSSEMM QHGQKELQSF
GEVAKRATPD IAPLRQYYTG ELAKIKDEIL ADKTIKDLSE FLYNILSVFT QTFGDSFKHF
SEFIENIYIS FDKTFGNILQ IIEKDILPHA KVTCDKFLKL FLHAVDIATH AVLTVGVQIA
DIAEKYQPEF QQLANVFGQV SQDVLRASLN LYEAVKSVII DQWQQIYNEI KAMPAVEQLK
AEYEQYVKHG LPARENIANA IKDLLSTIKD LAPTEELKAF IQAISDYVCP KLNNQKIDDK
VAIDRIIQSG IAGGKSIMAI VTGSRPVPEL HNFQLPLPAT LLNRLPKLAA FRFSPFSFIL
GEELYVSEFF LSLVNRPRNW IPPFPRKLQ
//
