ID A0A140L4R3_9CLOT Unreviewed; 769 AA.
AC A0A140L4R3;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Methyl-accepting chemotaxis protein McpB {ECO:0000313|EMBL:KXG75538.1};
GN Name=mcpB_2 {ECO:0000313|EMBL:KXG75538.1};
GN ORFNames=AN619_16800 {ECO:0000313|EMBL:KXG75538.1};
OS Thermotalea metallivorans.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Thermotalea.
OX NCBI_TaxID=520762 {ECO:0000313|EMBL:KXG75538.1, ECO:0000313|Proteomes:UP000070456};
RN [1] {ECO:0000313|EMBL:KXG75538.1, ECO:0000313|Proteomes:UP000070456}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B2-1 {ECO:0000313|EMBL:KXG75538.1,
RC ECO:0000313|Proteomes:UP000070456};
RA Patel B.K.;
RT "Draft genome sequence of the thermoanaerobe Thermotalea metallivorans, an
RT isolate from the runoff channel of the Great Artesian Basin, Australia.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXG75538.1}.
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DR EMBL; LOEE01000033; KXG75538.1; -; Genomic_DNA.
DR RefSeq; WP_068556274.1; NZ_LOEE01000033.1.
DR AlphaFoldDB; A0A140L4R3; -.
DR STRING; 520762.AN619_16800; -.
DR Proteomes; UP000070456; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd11386; MCP_signal; 1.
DR CDD; cd12914; PDC1_DGC_like; 1.
DR CDD; cd12912; PDC2_MCP_like; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR029151; Sensor-like_sf.
DR PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000070456};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW ProRule:PRU00284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 297..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 321..373
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 392..628
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
FT REGION 696..748
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 696..713
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 731..748
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 769 AA; 84745 MW; 698120E32891E481 CRC64;
MKLVKLKKKE EKKGQMGVQW KSKMAVQLAA VIVLIIAIAV TAIGTINYRS DIRDLLENKK
EANKIMAKVV ALQADLYITS SMETMRTLIA TVNFETLDEY GKNTTLGKMA SVNVQFKSVY
MTDMGGNVLA STNYRRDNGK NYKDTIWFKE AAAGRTYVSD TFIDEDSKMP VITIAMPIEN
IVSGQTGVMA ADLRLDRLFY LTKDMKIGET GYSYIVDKKG NIIAHPQFKE KVLTKYNALE
KGIKGVVSVI EGKSDVEIYE DTEGQKVVGG YAPVPSTKWG ILVEQQYREI TEQGRIALWR
TIVISLAVIL FGLLASVLFA RAFTKPITDM LKVVNKIKTG DLTERIKVNT TNEIGLLQKA
FNDMTASLAQ LIQDVSRLSG QINSSAKALE SNAQLTAEAA NDITMAIHEV VSGTEKQIHS
VERSTQAVSQ MIEGVRSVSD NAAEILKSSS YASELARNGA ENIEEIIKTM KSIDETVGES
AVLIKELSIH TYKIGDIVQL IKQISDQTNL LALNAAIEAA RAGEHGRGFA VVAEEVRKLA
EQSAKASANI VELIKKIEQE TDRVVKTMEC SLEGVKNGTK VVSGTTRSFH EIIQETQKVA
HEVESFTAAI EELTAGMDLV EHSMTEVNHV SQSTAASTQI VLASTQEQDN AIREITDFIG
GLSQMVHNLE QLIQRFNTGH GEASDRAVDD YGIEREQQET EDSMEKKEVG ETEDTAEIQE
ENTVSDGEEV PFGESGEELD PPVEEHDAWE EDVEFDLEGE RRETDAAGQ
//
