ID A0A140LB62_9CLOT Unreviewed; 460 AA.
AC A0A140LB62;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Major cardiolipin synthase ClsA {ECO:0000313|EMBL:KXG77787.1};
DE EC=2.7.8.- {ECO:0000313|EMBL:KXG77787.1};
GN Name=clsA_1 {ECO:0000313|EMBL:KXG77787.1};
GN ORFNames=AN619_03890 {ECO:0000313|EMBL:KXG77787.1};
OS Thermotalea metallivorans.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Thermotalea.
OX NCBI_TaxID=520762 {ECO:0000313|EMBL:KXG77787.1, ECO:0000313|Proteomes:UP000070456};
RN [1] {ECO:0000313|EMBL:KXG77787.1, ECO:0000313|Proteomes:UP000070456}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B2-1 {ECO:0000313|EMBL:KXG77787.1,
RC ECO:0000313|Proteomes:UP000070456};
RA Patel B.K.;
RT "Draft genome sequence of the thermoanaerobe Thermotalea metallivorans, an
RT isolate from the runoff channel of the Great Artesian Basin, Australia.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXG77787.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LOEE01000010; KXG77787.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A140LB62; -.
DR STRING; 520762.AN619_03890; -.
DR PATRIC; fig|520762.4.peg.437; -.
DR OrthoDB; 9762009at2; -.
DR Proteomes; UP000070456; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0008808; F:cardiolipin synthase activity; IEA:InterPro.
DR GO; GO:0032049; P:cardiolipin biosynthetic process; IEA:InterPro.
DR CDD; cd09110; PLDc_CLS_1; 1.
DR CDD; cd09112; PLDc_CLS_2; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR InterPro; IPR022924; Cardiolipin_synthase.
DR InterPro; IPR025202; PLD-like_dom.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR NCBIfam; TIGR04265; bac_cardiolipin; 1.
DR PANTHER; PTHR21248; CARDIOLIPIN SYNTHASE; 1.
DR PANTHER; PTHR21248:SF22; PHOSPHOLIPASE D; 1.
DR Pfam; PF13091; PLDc_2; 2.
DR SMART; SM00155; PLDc; 2.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR PROSITE; PS50035; PLD; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000070456};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KXG77787.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 198..225
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
FT DOMAIN 375..402
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
SQ SEQUENCE 460 AA; 53385 MW; 31CD23745743A8C0 CRC64;
MKKILFILIL IYFLFAIVKS FSLRWLLHML AIAFLLLAAL ALARDIQREY HKSIAKKNAE
YVHLLNQERS QGPRVIVQNV AETVCNIHIK EESPDGPYFH YVEILAHEKE AYDAMFQSIK
NAKHHIHAEY FIIKNDQIGT KIKNLLIQKK REGLEIRLIY DGFGSLLMQR KYIRELKNAG
IEVATFSPLW QGICNVSMNY RNHRKMLIID GETCMMGGRN IGDEYFGKKT KIGKWKDLDI
LLKGSGVAQV QSVFLRDWYM AKGQMLMDKK YYKENIENRE NIPVQIITGG PDSPQNHIEH
AYFSMVNAAR KQIFIITPYL IPTESMITAL ENAVFRGVDV QILIPINSDN LVAKYATNLW
AKRLAKSGVK VFQYQNGFIH SKMIAVDDKI ASIGTANFDY RGMQRDYEML AVIYHENYVR
QLKAYFQIFM DQSKKIEVEK REGFLDIMGM QFIKLIRESL
//
