ID A0A142L252_9BACT Unreviewed; 321 AA.
AC A0A142L252;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=3-phosphoglycerate dehydrogenase {ECO:0000313|EMBL:AMS26298.1};
GN ORFNames=AEM51_03930 {ECO:0000313|EMBL:AMS26298.1};
OS Bacteroidetes bacterium UKL13-3.
OC Bacteria; Bacteroidota.
OX NCBI_TaxID=1690483 {ECO:0000313|EMBL:AMS26298.1, ECO:0000313|Proteomes:UP000075224};
RN [1] {ECO:0000313|Proteomes:UP000075224}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Driscoll C.B.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|ARBA:ARBA00005854,
CC ECO:0000256|RuleBase:RU003719}.
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DR EMBL; CP012155; AMS26298.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A142L252; -.
DR STRING; 1690483.AEM51_03930; -.
DR KEGG; bbau:AEM51_03930; -.
DR PATRIC; fig|1690483.4.peg.836; -.
DR Proteomes; UP000075224; Chromosome.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05303; PGDH_2; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR029752; D-isomer_DH_CS1.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43761:SF1; 2-HACID_DH DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR43761; D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G13630); 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00065; D_2_HYDROXYACID_DH_1; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003719};
KW Reference proteome {ECO:0000313|Proteomes:UP000075224}.
FT DOMAIN 8..320
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 130..297
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 321 AA; 34493 MW; 54AD4EAD5EA874DB CRC64;
MTKILANDGI DANGKKILEA AGFTVDTTKI TQEKLATELN NYDAILVRSA TKVREDLIDA
CPNLKLIGRG GVGMDNIDVA YAKNKGIAVI NTPASSSVSV AELVFAHIFS GSRFIQITNR
VMPSKGNEEF GNLKKIASNG IELQGKTMGV YGFGRIGQEV AKIAIGLGMK VLAFDPYVET
LDLIVNLPAL GENSRIKVNI KTVSEESVIT HSDFITFHVP FNEGDKAIID AAKMAKMKKG
VGLINCSRGG VISETDLLAN LNSGHVAFAG LDVFEKEPPV NMDILQHDHV SVSPHIGGST
IEAQNRIGIE LAEKVIEFFK K
//
