ID A0A142LN84_9PROT Unreviewed; 656 AA.
AC A0A142LN84;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Type IV pilus biogenesis and competence protein PilQ {ECO:0000256|ARBA:ARBA00014124};
GN ORFNames=AEM42_07065 {ECO:0000313|EMBL:AMS33680.1};
OS Betaproteobacteria bacterium UKL13-2.
OC Bacteria; Pseudomonadota; Betaproteobacteria.
OX NCBI_TaxID=1690485 {ECO:0000313|EMBL:AMS33680.1, ECO:0000313|Proteomes:UP000075227};
RN [1] {ECO:0000313|Proteomes:UP000075227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Driscoll C.B.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for type IV pilus biogenesis and competence. Could
CC function as a pore for exit of the pilus but also as a channel for
CC entry of heme and antimicrobial agents and uptake of transforming DNA.
CC {ECO:0000256|ARBA:ARBA00024678}.
CC -!- SUBUNIT: Homododecamer. Tetramer of trimer.
CC {ECO:0000256|ARBA:ARBA00025897}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane
CC {ECO:0000256|RuleBase:RU004004}.
CC -!- SIMILARITY: Belongs to the bacterial secretin family. GSP D subfamily.
CC {ECO:0000256|ARBA:ARBA00006980}.
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DR EMBL; CP012157; AMS33680.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A142LN84; -.
DR STRING; 1690485.AEM42_07065; -.
DR KEGG; beb:AEM42_07065; -.
DR PATRIC; fig|1690485.4.peg.1595; -.
DR Proteomes; UP000075227; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015627; C:type II protein secretion system complex; IEA:InterPro.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:UniProtKB-KW.
DR GO; GO:0015628; P:protein secretion by the type II secretion system; IEA:InterPro.
DR Gene3D; 3.30.1370.120; -; 3.
DR InterPro; IPR049371; GspD-like_N0.
DR InterPro; IPR001775; GspD/PilQ.
DR InterPro; IPR005644; NolW-like.
DR InterPro; IPR038591; NolW-like_sf.
DR InterPro; IPR004846; T2SS/T3SS_dom.
DR InterPro; IPR013356; T2SS_GspD.
DR InterPro; IPR004845; T2SS_GspD_CS.
DR NCBIfam; TIGR02517; type_II_gspD; 1.
DR PANTHER; PTHR30332; PROBABLE GENERAL SECRETION PATHWAY PROTEIN D; 1.
DR PANTHER; PTHR30332:SF24; SECRETIN XPSD; 1.
DR Pfam; PF00263; Secretin; 1.
DR Pfam; PF03958; Secretin_N; 3.
DR Pfam; PF21305; type_II_gspD_N0; 1.
DR PRINTS; PR00811; BCTERIALGSPD.
DR PROSITE; PS00875; T2SP_D; 1.
PE 3: Inferred from homology;
KW Competence {ECO:0000256|ARBA:ARBA00023287};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000075227};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane beta strand {ECO:0000256|ARBA:ARBA00022452};
KW Transport {ECO:0000256|RuleBase:RU004004}.
FT DOMAIN 22..90
FT /note="GspD-like N0"
FT /evidence="ECO:0000259|Pfam:PF21305"
FT DOMAIN 116..176
FT /note="NolW-like"
FT /evidence="ECO:0000259|Pfam:PF03958"
FT DOMAIN 180..251
FT /note="NolW-like"
FT /evidence="ECO:0000259|Pfam:PF03958"
FT DOMAIN 259..346
FT /note="NolW-like"
FT /evidence="ECO:0000259|Pfam:PF03958"
FT DOMAIN 436..603
FT /note="Type II/III secretion system secretin-like"
FT /evidence="ECO:0000259|Pfam:PF00263"
FT REGION 631..656
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 656 AA; 68845 MW; D0C5F18F82F208C1 CRC64;
MIGIFATSGL RIASAQDTIT MSFVNADIRS VVETIGKATG KNFIIDPRVT GNMNIVSQTP
VTKDLAYEIL LSSLRVQGFA VIEERGAVKI VPEADAKTSG QVIAPGAVVK GDRIVTQVFA
LQNESAAQLA TVLRPLVAQN NFIGAYPGNN TLVITDYASN VERIRKIITA IDVPGSSDLQ
TVKLQYASAV DIANTIVRLL PEASLNPSNP GAPAKLSVGV EPRTNSLIIR ADSPALIARL
RALVAQIDTP TAANGNINVV YLKNAEATRI AETLRGLMGG ASASTSSLPA ANNAAGAQTN
LASSSPAPAS NIQAYAATNS LIITAPDHVY NSLRSVIDKL DQRRAQVYVE ALIVEVTSSV
AAEFGIQWQD LTGINRSGAQ VIGGTNFGSA SAGTNIISSA QNITSVSQGL NIGVVRGQVT
IPGIGTVLNL GALARALEND QRANVLSTPN ILTLDNEEAK IVVGQNVPFV TGSYTQSTNT
STNPFQTIER KDIGLTLRVT PQVAEGGAVK LKVFQEVSSV VPSSSTVKSA DLITNKRSIE
NTVLVDDGQT VVIGGLISDD TKNGDSKVPL LGDIPVIGNL FKYQTRNRDK TNLMVFLRPI
VIRDGKGAAQ LTGSRYDYIR GEQAAHLKDG ESLLPPTGGP QLPPLTAVPA PIAEKK
//
