ID A0A150WN02_BDEBC Unreviewed; 640 AA.
AC A0A150WN02;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Sulfatase {ECO:0000313|EMBL:KYG65790.1};
GN ORFNames=AZI86_01570 {ECO:0000313|EMBL:KYG65790.1};
OS Bdellovibrio bacteriovorus.
OC Bacteria; Bdellovibrionota; Bdellovibrionia; Bdellovibrionales;
OC Pseudobdellovibrionaceae; Bdellovibrio.
OX NCBI_TaxID=959 {ECO:0000313|EMBL:KYG65790.1, ECO:0000313|Proteomes:UP000075320};
RN [1] {ECO:0000313|EMBL:KYG65790.1, ECO:0000313|Proteomes:UP000075320}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R0 {ECO:0000313|EMBL:KYG65790.1,
RC ECO:0000313|Proteomes:UP000075320};
RA Ploux O.;
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYG65790.1}.
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DR EMBL; LUKE01000001; KYG65790.1; -; Genomic_DNA.
DR RefSeq; WP_061833334.1; NZ_LUKE01000001.1.
DR AlphaFoldDB; A0A150WN02; -.
DR Proteomes; UP000075320; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd16015; LTA_synthase; 1.
DR Gene3D; 3.30.1120.80; -; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR012160; LtaS-like.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR47371; LIPOTEICHOIC ACID SYNTHASE; 1.
DR PANTHER; PTHR47371:SF3; PHOSPHOGLYCEROL TRANSFERASE I; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR PIRSF; PIRSF005091; Mmb_sulf_HI1246; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Manganese {ECO:0000256|PIRSR:PIRSR005091-2};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR005091-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000075320};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 51..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 82..104
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 276..547
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
FT ACT_SITE 323
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-1"
FT BINDING 284
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
FT BINDING 439
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-2"
FT BINDING 493
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
FT BINDING 494
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
SQ SEQUENCE 640 AA; 73119 MW; BF58AE547497EF44 CRC64;
MFGPSYRPLK VFSLALVALV FYSFARAEFL IWNWALFKTK PFLDILWSFV VGLRFDIAGV
LSVSAPILLL SFFPWPKNGN RAWMWVTGFF FCLLHVPFLV LNLVDTEFIN FVGRRFSYDG
LFIANEVPGK FWNFVASYWL LFLINTLLVI FFVITVVAVL RRTPKNLYWF KELSPGKKVK
AGMGHALICL GCIALAVIGI RGGLQKKPVN FVSANVFTAP LLNNLVLNST FTLIKSYGAQ
TLKQEKYFSD KEEMLSLLNG SLGPSHMEGK RPTQKQNIVI IMLESFGEEY LGPHNGKSYT
PFLDRLSQNA LVFRNGYANG RRSIEGVGAI MGGIPALMAE PFISSHFTSN YFLGLGTLLG
QQGYSTSFFH GGHNGTMYFD SFMQSAGVEK YYGATEYNNP ADDDGVWGIW DEPFLQWMVA
KLDNQPQPFM TSVFTLTSHQ PYKIPAQYRD KFPEGPIEIL KAIEYTDYSL QKFFESAQKK
SWYPNTLFVI MADHTSIHYR KEYENDIGSY RIPFILYHPT MTLPKVDTSM VVQQIDVPPT
VLDFLNISPK DKNYLGSSIF VEGDKVAVNF IDGRYLLFAR DAYMRWTPGH GEPQMYAITD
LDSERELQGE RKELLIRKLK AHIQYFNEGM WDNKLYYPAK
//
