ID A0A151B0U9_9CLOT Unreviewed; 385 AA.
AC A0A151B0U9;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=ribose-phosphate diphosphokinase {ECO:0000256|ARBA:ARBA00013247};
DE EC=2.7.6.1 {ECO:0000256|ARBA:ARBA00013247};
GN Name=prs_2 {ECO:0000313|EMBL:KYH33267.1};
GN ORFNames=CLTEP_21600 {ECO:0000313|EMBL:KYH33267.1};
OS Clostridium tepidiprofundi DSM 19306.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1121338 {ECO:0000313|EMBL:KYH33267.1, ECO:0000313|Proteomes:UP000075531};
RN [1] {ECO:0000313|EMBL:KYH33267.1, ECO:0000313|Proteomes:UP000075531}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19306 {ECO:0000313|EMBL:KYH33267.1,
RC ECO:0000313|Proteomes:UP000075531};
RA Poehlein A., Daniel R.;
RT "Genome sequence of Clostridium tepidiprofundi DSM 19306.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ribose-phosphate pyrophosphokinase family.
CC {ECO:0000256|RuleBase:RU004324}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYH33267.1}.
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DR EMBL; LTBA01000034; KYH33267.1; -; Genomic_DNA.
DR RefSeq; WP_066826585.1; NZ_LTBA01000034.1.
DR AlphaFoldDB; A0A151B0U9; -.
DR STRING; 1121338.CLTEP_21600; -.
DR PATRIC; fig|1121338.3.peg.2250; -.
DR OrthoDB; 9777067at2; -.
DR Proteomes; UP000075531; Unassembled WGS sequence.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
DR GO; GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd06223; PRTases_typeI; 1.
DR Gene3D; 3.40.50.2020; -; 2.
DR InterPro; IPR029099; Pribosyltran_N.
DR InterPro; IPR000836; PRibTrfase_dom.
DR InterPro; IPR029057; PRTase-like.
DR InterPro; IPR005946; Rib-P_diPkinase.
DR NCBIfam; TIGR01251; ribP_PPkin; 1.
DR PANTHER; PTHR10210:SF32; RIBOSE-PHOSPHATE DIPHOSPHOKINASE; 1.
DR PANTHER; PTHR10210; RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER; 1.
DR Pfam; PF00156; Pribosyltran; 1.
DR Pfam; PF13793; Pribosyltran_N; 1.
DR SMART; SM01400; Pribosyltran_N; 1.
DR SUPFAM; SSF53271; PRTase-like; 2.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|EMBL:KYH33267.1};
KW Nucleotide biosynthesis {ECO:0000256|ARBA:ARBA00022727,
KW ECO:0000256|RuleBase:RU004324};
KW Reference proteome {ECO:0000313|Proteomes:UP000075531};
KW Transferase {ECO:0000313|EMBL:KYH33267.1}.
FT DOMAIN 16..161
FT /note="Ribose-phosphate pyrophosphokinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13793"
FT DOMAIN 191..304
FT /note="Phosphoribosyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00156"
SQ SEQUENCE 385 AA; 43838 MW; 61E1E7978FAD803F CRC64;
MSIDSINLTS YGQLGIIALE SCKKMGNKID NHLQKKRRIG VSNDSKTEDS NKKSYLIAID
EIRFSNGEGK VKLEESVRGK DIYILCDVGN YSCTYDMFGF KNHKGPDEHF QDIKRVVSAI
GGKARRITVI MPLLYAGRQH RRRGRESLDC AIALQELERL GVGHIITFDV HDPNVQNAIP
LISFDSLYPT YEIVKTFLKE ENDLVIDKTK MIVISPDTGA MDRAVYYSSV LGVDVGLFYK
RRDHSIIVHG KNPIIQHEYI GRNVEGKDIL IVDDMIASGE SIFDIVKELK KRNARKIFVA
TSFALFTEGI EKFNKFYEMG LIDRVYSTNL TYISQKVKDS KWYKEVDMSE LIADLINNIN
YDKSIDPLLD ATESIKQLLN KTILE
//
