ID A0A151GAZ6_9HYPO Unreviewed; 1000 AA.
AC A0A151GAZ6;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 13-SEP-2023, entry version 34.
DE RecName: Full=Guanine-nucleotide exchange factor Cdc24 {ECO:0008006|Google:ProtNLM};
GN ORFNames=DCS_06236 {ECO:0000313|EMBL:KYK54279.1};
OS Drechmeria coniospora.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Drechmeria.
OX NCBI_TaxID=98403 {ECO:0000313|EMBL:KYK54279.1, ECO:0000313|Proteomes:UP000076580};
RN [1] {ECO:0000313|EMBL:KYK54279.1, ECO:0000313|Proteomes:UP000076580}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 6962 {ECO:0000313|EMBL:KYK54279.1,
RC ECO:0000313|Proteomes:UP000076580};
RX PubMed=26975455; DOI=10.1038/srep23122;
RA Zhang L., Zhou Z., Guo Q., Fokkens L., Miskei M., Pocsi I., Zhang W.,
RA Chen M., Wang L., Sun Y., Donzelli B.G., Gibson D.M., Nelson D.R.,
RA Luo J.G., Rep M., Liu H., Yang S., Wang J., Krasnoff S.B., Xu Y.,
RA Molnar I., Lin M.;
RT "Insights into Adaptations to a Near-Obligate Nematode Endoparasitic
RT Lifestyle from the Finished Genome of Drechmeria coniospora.";
RL Sci. Rep. 6:23122-23122(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYK54279.1}.
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DR EMBL; LAYC01000003; KYK54279.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151GAZ6; -.
DR STRING; 98403.A0A151GAZ6; -.
DR InParanoid; A0A151GAZ6; -.
DR OrthoDB; 23973at2759; -.
DR Proteomes; UP000076580; Chromosome 03.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd00014; CH_SF; 1.
DR CDD; cd05992; PB1; 1.
DR CDD; cd13246; PH_Scd1; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR010481; Cdc24/Scd1_N.
DR InterPro; IPR033511; Cdc24/Scd1_PH_dom.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR001331; GDS_CDC24_CS.
DR InterPro; IPR000270; PB1_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR47339; CELL DIVISION CONTROL PROTEIN 24; 1.
DR PANTHER; PTHR47339:SF1; CELL DIVISION CONTROL PROTEIN 24; 1.
DR Pfam; PF06395; CDC24; 1.
DR Pfam; PF00564; PB1; 1.
DR Pfam; PF15411; PH_10; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS00741; DH_1; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS51745; PB1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000076580}.
FT DOMAIN 237..411
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 900..998
FT /note="PB1"
FT /evidence="ECO:0000259|PROSITE:PS51745"
FT REGION 18..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 590..779
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 820..897
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 622..644
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 689..727
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 763..779
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 820..835
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 876..897
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1000 AA; 109265 MW; ADFCAB4D42A8D15F CRC64;
MAHAPLLGNL SGSIFPPPSL SGAGSLQQNS KTSMSHAPRT SQLPGPPAFA ASSSSLSTLS
SGGTVVSGTN GGPIAATGNI INQKADASRS LYQICISLKQ RLAQVPGFGH FLEKLDPNDP
VDPLWTLLRT GYPLLAIYNS LQPAERLKVD DPNAAEAKKS KIAIFKFVQA CMKELNVPPA
DCFVITDLTG TDTSGFVKVT QVVNYVLDLA EERGLLLQQQ HPKGEPLTAT GSSQMSYRDH
IVKELVDTER KYVQDLENLQ GLKKTLEQKG AIPGDIVHQI FLNINAILDF QRRFLIRVET
TNSMPTADQR WGAPFCFYED AFDIYQPFIA NQRKAAHLAN QVFDNIQSSD HPVAADFNTL
DGFLLKPMQR LVKYPLLLKD LNKKTENDEV KEDLMMGCEA AERVLSKANE AVNRDLLDEA
LEELVQRVDD WKSHKVDSFG KLLLHGVYGV ITGKSDQEKE YEIYLFECIL LCCKEASANK
SKDKKDKTRS SGPRIRNKNA KLQLKGRIFM TNVTDIVSLS KPGSHSVQIW WKGDPGVENF
TIRFLNEETM KKWAMGLEAQ RKEYVPRLSS SSEGATDFAW TRDQAGALEN PYLQDDDDDE
EEYGSTTAPS QFPMPVLPPV GSSLPRTSSS SNPRQRSATG DSTHSLAGVA RAPPPRLPLP
PPPGALSVQT HGNGATSPGL RGGDSYFSPV AESPTSSRAS AASGMFPSHT FSYPKSGTPQ
PTWDETNRYT APAMPRAPSR DGTSPGPHML NARNPRGPSL PPMATPNQSA AQKQRSRSYS
TTDANGMARV RQQGQVPAMP TIPTHLAHDG NILRAQNASP RNELPVRTST QSPGTQRERM
HKHSGSLGGQ MAQIPGKQAY QRQPSGAPPG AGSFRVDSMS ATSRTMSPAQ SMQGSEMPLP
TQLKVRVNCD SGNYVTLVVA FNITYQSLID RIDAKLARFM TNNIGKGMLK LRYRDEDGDF
VTIASDDDIQ IAFMEWHEGV KNMYSGGVGE IELFCVGDTS
//
