ID   A0A151M7B5_ALLMI        Unreviewed;       363 AA.
AC   A0A151M7B5;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Homeobox protein Meis3 isoform A {ECO:0000313|EMBL:KYO20406.1};
GN   Name=MEIS3 {ECO:0000313|EMBL:KYO20406.1};
GN   ORFNames=Y1Q_0012444 {ECO:0000313|EMBL:KYO20406.1};
OS   Alligator mississippiensis (American alligator).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC   Alligator.
OX   NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO20406.1};
RN   [1] {ECO:0000313|EMBL:KYO20406.1, ECO:0000313|Proteomes:UP000050525}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO20406.1};
RX   PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA   St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA   Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA   Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA   Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA   Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA   McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA   Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA   Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA   Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA   Ray D.A.;
RT   "Sequencing three crocodilian genomes to illuminate the evolution of
RT   archosaurs and amniotes.";
RL   Genome Biol. 13:415-415(2012).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108}.
CC   -!- SIMILARITY: Belongs to the TALE/MEIS homeobox family.
CC       {ECO:0000256|ARBA:ARBA00009661}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KYO20406.1}.
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DR   EMBL; AKHW03006431; KYO20406.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A151M7B5; -.
DR   eggNOG; KOG0773; Eukaryota.
DR   Proteomes; UP000050525; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR008422; Homeobox_KN_domain.
DR   InterPro; IPR032453; PKNOX/Meis_N.
DR   PANTHER; PTHR11850:SF190; HOMEOBOX PROTEIN MEIS3-RELATED; 1.
DR   PANTHER; PTHR11850; HOMEOBOX PROTEIN TRANSCRIPTION FACTORS; 1.
DR   Pfam; PF05920; Homeobox_KN; 1.
DR   Pfam; PF16493; Meis_PKNOX_N; 1.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
KW   ECO:0000313|EMBL:KYO20406.1};
KW   Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW   ProRule:PRU00108};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000050525}.
FT   DOMAIN          261..324
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000259|PROSITE:PS50071"
FT   DNA_BIND        263..325
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT   REGION          25..59
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          212..268
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          326..363
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   363 AA;  39199 MW;  BE319E2DED9655D1 CRC64;
     MAQRYEDLAC YPAMDGLPLP GFADPHLGRS LPPPSLSQSS PYGPSGVSHR AGAPAGIGNG
     DALKREKDEI YGHPLFPLLA LVFEKCELAT CSPRDAPGTC PGADVCSSDS FNEDIAVFAK
     QVRTEKPLFS SNPELDNLMI QAIQVLRFHL LELEKVHDLC DNFCHRYITC LKGKMPIDLV
     IDDRDGSKSD LEDYACPSLS DQGSVWLRDA EEVAPAGTPG PSSGGGLASH SGDNSSEAGD
     GLDAGAASPS TGDEDELERD KKRSKKRGIF PKVATNIMRA WLFQHLSHPY PSEEQKKQLA
     QDTGLTILQV NNWFINARRR IVQPMIDQSN RSGPGAPYSP EGAPLGGYGL EGQQHLGVRP
     PEL
//