ID A0A151MBL7_ALLMI Unreviewed; 1191 AA.
AC A0A151MBL7;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=SH3 and multiple ankyrin repeat domains protein 2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=Y1Q_0000548 {ECO:0000313|EMBL:KYO21869.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO21869.1};
RN [1] {ECO:0000313|EMBL:KYO21869.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO21869.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO21869.1}.
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DR EMBL; AKHW03006283; KYO21869.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151MBL7; -.
DR STRING; 8496.A0A151MBL7; -.
DR eggNOG; KOG4375; Eukaryota.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR041489; PDZ_6.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR24135; SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN; 1.
DR PANTHER; PTHR24135:SF17; SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN 2; 1.
DR Pfam; PF17820; PDZ_6; 1.
DR Pfam; PF07653; SH3_2; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 70..129
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 170..264
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 1..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 269..288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 407..470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 539..722
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 793..820
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 848..901
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 945..993
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1007..1037
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1136..1167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..26
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 411..434
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 435..464
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 561..598
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 653..722
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 800..820
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 961..993
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1144..1167
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1191 AA; 129813 MW; E935B55AA55DD137 CRC64;
MQNNPNGTVK TVGSYTPSSR SRSPSLNRLG EDAKRQQHRH ISAGYNPSAN KDTISALDYQ
GPKRKLYSAV PGRLFIVVKP YQPQGEGEIH LHKGDRVKVL SIGEGGFWEG STRGHVGWFP
ADCVEEVQCK PNESKPETRA DRTKKLFRHY TVGSYDSFDA SSDCIIEEKA VVLQKKDNEG
FGFVLRGAKA DTPIEEFTPT PAFPALQYLE SVDEGGVAWQ AGLRTGDFLI EVNNENVVKV
GHRQVVNMIR QGGNHLVLKV VTVTRSLDPD DTARKKAPPP PKRAPTTALT LRSKSMTSEL
EELDKVDEIV PVSKPSRIAD NATVDSRVAT IKQRPSSRCF PSVTDMNSMY ERQGIAVMPP
TVPGSPQGPF LGIPRGTMRR QKSIGITEEE RQFLAPPMLK FTRSLSMPDT SEEIPPPPQS
LPPSPPPPSP SLYNSPKSPT SRSYGTIKPA FNQNSGSKVS SGRPENMGTM IREKGMYYRR
ELDRYSLDSE DLYSRNAATQ ANFRSKRGQM PENPYSEVGK IASKAVYVPA KPARRKGMLV
KQSNVEDSPE KTCSIPIPTI IVKEPSTSSS GKSSQGSSME IDPQSSEQPG QLRPDDNLNV
SSPFAAAIAG AVRDREKRLE ARRNSPAFLS TDLGDEDVGL TPPTPRLRQS KFTEEGMFSN
EESFRQLMSP SPIPTPRESE NLFNNSEPSD QTDARTVNSS SKPKGTENNV VVTKPTSVPS
SDNYVHPLTG KLLDPNSPLA LALSARDRAM KEQTQQIPGK GEASKADLNK PLYIDTKLRP
NIETTFPVTA TVTRQNTRGP LRRQETENKY ETDMGKEKKP EEKKNMLINI VDTSQQKSAG
LLMVHTVDTA KSDDTPEDEE KIIEAEVNPE SSSPEVPEGS EEAESGLSVS ATPEPPPSPC
KTIVAASSVD DPVILPFRIP PPPLASVDID EEFIFTEPLP PPLEFANSFD IPDDRSAPGS
ALTDSLKQRQ TGTPSPASFN PNQPTNSLDS KKQVGLSNCL PASFLPPPES FDNITDSGIE
EVDSRSSSDH HLETTSTIST VSSISTLSSE GGENLDTCTV YADGQTFLVD KPPVPPKPKM
KPIINKSNAL YKDALIEETV DSFVIPPPAP PPPPISAQPN MAKVVPQRTS KLWGDVTEPG
EGLESPTGTK TASLSTRSTE VMSTVSGTRS TTITFTVRPG TNQPITLQSR Y
//
