ID A0A151MS12_ALLMI Unreviewed; 476 AA.
AC A0A151MS12;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=TOX high mobility group box family member 3 isoform A {ECO:0000313|EMBL:KYO27312.1};
GN Name=TOX3-1 {ECO:0000313|EMBL:KYO27312.1};
GN ORFNames=Y1Q_0021239 {ECO:0000313|EMBL:KYO27312.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO27312.1};
RN [1] {ECO:0000313|EMBL:KYO27312.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO27312.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO27312.1}.
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DR EMBL; AKHW03005226; KYO27312.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151MS12; -.
DR STRING; 8496.A0A151MS12; -.
DR eggNOG; KOG0381; Eukaryota.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd21995; HMG-box_TOX-like; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR PANTHER; PTHR45781; AGAP000281-PA; 1.
DR PANTHER; PTHR45781:SF3; TOX HIGH MOBILITY GROUP BOX FAMILY MEMBER 3; 1.
DR Pfam; PF00505; HMG_box; 1.
DR PRINTS; PR00886; HIGHMOBLTY12.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; HMG-box; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525}.
FT DOMAIN 260..328
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 260..328
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 192..263
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 428..449
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 192..223
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 224..245
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 476 AA; 50846 MW; 64E473AD309792B3 CRC64;
MDVRFYPAAA GSALPGDPAS LDFAQCLGYY SYGKFGNNNN YMNMAEANNA FLTANEQTFH
TPSLGDEEFE IPPITPPPES DPTLGMADIL LPFQGLGEQL SAQGNEFTPQ FPPQSLDLPS
ITISRNLVEQ DGVVHTNGLH MDQNHTPVSQ YRQDPSLIMR SIVHMTDAAR SGIMPPTQLT
TINQSQLSTQ LGLNLGGTNL PHTSPSPPAS KSATPSPSSS INEEDADESN RAAGEKRAAP
DSGKKPKTPK KKKKKDPNEP QKPVSAYALF FRDTQAAIKG QNPNATFGEV SKIVASMWDS
LGEEQKQVYK RKTEAAKKEY LKALAAYRAS LVSKAAAESA EAQTIRSVQQ TLASTNLSSS
LILNAPLSQH ATVSASPQTL QQSLPRAIAP KPLTMRLPMN QIVASVTIAP NMPTNIAAPL
ISSMGTNMVA TPSSSQPSAS PSAASVTNTI PDTDSSVITA LPTICESNRL INTWTF
//
