ID A0A151N816_ALLMI Unreviewed; 1760 AA.
AC A0A151N816;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Kinase D-interacting substrate of {ECO:0000313|EMBL:KYO32964.1};
GN Name=KIDINS220 {ECO:0000313|EMBL:KYO32964.1};
GN ORFNames=Y1Q_0011288 {ECO:0000313|EMBL:KYO32964.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO32964.1};
RN [1] {ECO:0000313|EMBL:KYO32964.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO32964.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO32964.1}.
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DR EMBL; AKHW03003826; KYO32964.1; -; Genomic_DNA.
DR STRING; 8496.A0A151N816; -.
DR eggNOG; KOG0502; Eukaryota.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR011646; KAP_P-loop.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR24116; KINASE D-INTERACTING SUBSTRATE OF 220 KDA; 1.
DR PANTHER; PTHR24116:SF0; KINASE D-INTERACTING SUBSTRATE OF 220 KDA; 1.
DR Pfam; PF00023; Ank; 2.
DR Pfam; PF12796; Ank_2; 4.
DR Pfam; PF07693; KAP_NTPase; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 11.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 8.
DR PROSITE; PS50088; ANK_REPEAT; 9.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Kinase {ECO:0000313|EMBL:KYO32964.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000313|EMBL:KYO32964.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 494..514
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 521..543
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 657..677
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 689..709
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 33..65
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 99..131
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 133..165
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 166..198
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 199..231
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 232..264
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 265..297
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 331..363
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 364..387
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 437..949
FT /note="KAP NTPase"
FT /evidence="ECO:0000259|Pfam:PF07693"
FT REGION 1160..1186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1327..1355
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1385..1486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1508..1555
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1567..1604
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1672..1693
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1332..1355
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1385..1418
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1420..1443
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1444..1461
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1520..1554
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1577..1591
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1760 AA; 195189 MW; 812A91140F6E5252 CRC64;
MTQSLLTYVE EGNVPALKAL LEKCKDVDER NENGQTPLML AAEQGNLEIV QELLKKGANC
NLEDSDNWTA LISASKEGHV DIVAELLNCN VNLEHRDMGG WTALMWASYK GRTEVAELLL
EKGSNPNITG LQYSVYPVIW AAGRGHSDIV RLLLQHGAKV NCSDKYGTTP LIWAARKGHL
ECVKYLLQMG ADVDQEGANS MTALIVAVKG GYTDSVKEIL KRNPNVNLTD KDGNTALMIA
SKEGHTEIVQ DLLDAGTYVN IPDRSGDTVL IGAVRGGHVE IVRALLHKYA DIDIRGQDNK
TALYWAVEKG NATMVRDILQ CNPDTEICTK DGETPLIKAT KMRNIEIVEL LLDKGAKVSA
IDKKGDTPLH IAIRGRSRKL AELLLRNPKD GRLLYRPNKA GETPYNIDCS HQKSILTQIF
GARHLSPTES DGDMLGYDLY SSALADILSE PTMQPPICVG LYAQWGSGKS FLLKKLEDEM
KTFAGQQIEP LFQFSWLIVF LTLMVCGGLG LLLAFTVDTK LGIAVALSLL AVLYIFFAVI
YFGGQREGES WNWAWVLSTR LARHIGYLEL LLKLMFVNPP ELPEQTTKAL PVRFLFTDYN
RLSSVGGETS LAEMIATLSD ACEREFGFLA TRLFRVFKTE DTQGKKKWKK TCCLPSFVIF
LFILSCIIAG ITLLAIFNID PKNMTVNAIL ISVACVVGLA FILNCRTWWQ VIDSVLNSQR
KRLHNAASKL HKLKSEGFMK VLKCEVELMA KMAKTIDSFT QNQTRLVVII DGLDACEQDK
VLQMLDTVRV LFSKGPFIAI FASDPHIIIK AINQNLNSVL RDSNINGHDY MRNIVHLPVF
LNSRGLSSAK KLMVAATTNG DVPYSDNAGF HEEVDRRVSQ NSLGEMTKLG SKTALNRRDT
YRRRQMQRTI TRQMSFDLTK LLVTEDWFSD ISPQTMRRLL NIVSVTGRLL RANQITFNWD
RLASWINLTE QWPYRTSWLI LYLEETEGVP DQLTLKTIYE RISKNIPTTK DVEPLLEIDG
DIRNFEVFLS SRTPVLIARD VKIFLPCTVN LDPKLREIIA DVRAARDQMN IGGLPYPTLP
LHEAPARASS VFSQPSSVCS SSTSFNGPFN GGVLSPQPHS SYYSGMTGPQ HPFYNRPFFA
PYVYMPRYYP GSSHLISRPP LKTSLSRDQN NGLGSGAITG SATGGSHASL SSMTVESICE
KLKQIEGLDQ NMLSQYCATI KKANINGRVL AQCNTEELKR EMNMNFGDWH LFKSMVLEMR
NSENQAIHED SRGGSEHVTN VIPHNELARR SGHNSELPHT ELTGLSGQAP YALNFSFEEL
NTIGLDEAPP RHSNLSWQSQ TRRTPSLSSL NSQDSSIEIS KLTDKVQAEY RDAYREYIAQ
MSQLEGGASS TTVSGRSSPH STTAFYMGQS TSGGSLHSGI EQEKGKDGEQ KQDDGRKSFL
LKRNDVDYST SGVSTNDASP LDPITEEDEK SDQSGSKLLP GKKSSERTSI FQAADIKLKG
VTLRYQKLPS DEDESGTEES DNTPLLKEGK DKKMDGKMDK QPKSPEHGSE PIRTFIKAKE
YLTDALLDKK DSSDSGVRSS ESSPNHSLHN EGADDSQLEK ANLIELEDDS HSGKRGIPHS
LSGLQDPAVV RMSICSEDKK SPSESSLIAS SPEENWPACQ KVYNLNRTPS TVTLNNNSAP
ANRGNQNFEE TEGIRESPQI ILRPGTSSNS TVVQNENLKS VAHKRSQRSS YTRLSKDASE
LHTVTASDAA GFGEERESIL
//
