ID A0A151NBA8_ALLMI Unreviewed; 570 AA.
AC A0A151NBA8;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Otolin-1 {ECO:0000313|EMBL:KYO34047.1};
GN Name=OTOL1 {ECO:0000313|EMBL:KYO34047.1};
GN ORFNames=Y1Q_0024633 {ECO:0000313|EMBL:KYO34047.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO34047.1};
RN [1] {ECO:0000313|EMBL:KYO34047.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO34047.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO34047.1}.
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DR EMBL; AKHW03003627; KYO34047.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151NBA8; -.
DR STRING; 8496.A0A151NBA8; -.
DR eggNOG; ENOG502QRPC; Eukaryota.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.40; -; 1.
DR InterPro; IPR001073; C1q_dom.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR PANTHER; PTHR15427:SF49; C1Q DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR15427; EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER; 1.
DR Pfam; PF00386; C1q; 1.
DR Pfam; PF01391; Collagen; 1.
DR PRINTS; PR00007; COMPLEMNTC1Q.
DR SMART; SM00110; C1Q; 1.
DR SUPFAM; SSF49842; TNF-like; 1.
DR PROSITE; PS50871; C1Q; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..570
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007585901"
FT DOMAIN 431..566
FT /note="C1q"
FT /evidence="ECO:0000259|PROSITE:PS50871"
FT REGION 206..445
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..314
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 321..364
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 570 AA; 60753 MW; 2A04D68ACDE563B3 CRC64;
MNCSSSKSLW DMAWIFLAWI DRAWNLTCHH PDSLIAGTWQ KASKKQVKRR VLACGLHLHF
LRFQCHSGYF QETSPIPFPL CTANPLIGYN KTTKMGNFPW QSATLSIIII AAVHTEAKTT
QKPHAKFTKI KVPEVEVTEG FDTSIVPPTG ESSFPEISEM SEMTTDLSTL HPAFRTATTL
FPFENFTLDT ADFFFNCCDC CTPASGQKGE PGDHGLPGPK GETGDTGLQG LPGIPGFQGP
KGFKGEKGDK GEHGDQGTNG IPGYPGKPGE PGETGAKGDK GNHGLPGIKG QKGVKGDTCD
NGTKGEKGDK GELGLPGLDG ENGDKGEKGD MGEKGHCGEP GERGEKGEKG EVGMKGEKGS
KGDIGVEGIH GTDGKQGEKG APGSKGEKGD LGPVGMMGPL GPKGIPGSKG ARGALGKKGA
RGVKGSKGDN SKVPRSAFSA SLSKPFPPPN TPIKFDKILY NDQEDYNPST GKFNCSIPGA
YVFTYHLTVR GRPARISLVA QNKKMVKTRE TLYGQEIDQA SFLIILKLNA GDQVWLEVAR
DWNGVYVSAE DDSIFTGFLL YPDDVFETLV
//
