ID A0A151NBT0_ALLMI Unreviewed; 680 AA.
AC A0A151NBT0;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=Transcription initiation factor TFIID subunit 8 {ECO:0000256|ARBA:ARBA00017307};
DE AltName: Full=TBP-associated factor 8 {ECO:0000256|ARBA:ARBA00031721};
GN Name=TAF8-1 {ECO:0000313|EMBL:KYO34241.1};
GN ORFNames=Y1Q_0023684 {ECO:0000313|EMBL:KYO34241.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO34241.1};
RN [1] {ECO:0000313|EMBL:KYO34241.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO34241.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TAF8 family.
CC {ECO:0000256|ARBA:ARBA00008767}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO34241.1}.
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DR EMBL; AKHW03003562; KYO34241.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151NBT0; -.
DR eggNOG; KOG4336; Eukaryota.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR GO; GO:0008061; F:chitin binding; IEA:InterPro.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd08049; TAF8; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR006565; BTP.
DR InterPro; IPR011583; Chitinase_II.
DR InterPro; IPR029070; Chitinase_insertion_sf.
DR InterPro; IPR001223; Glyco_hydro18_cat.
DR InterPro; IPR001579; Glyco_hydro_18_chit_AS.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR037818; TAF8.
DR InterPro; IPR019473; TFIID_su8_C.
DR PANTHER; PTHR46469; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8; 1.
DR PANTHER; PTHR46469:SF1; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8; 1.
DR Pfam; PF07524; Bromo_TP; 1.
DR Pfam; PF00704; Glyco_hydro_18; 1.
DR Pfam; PF10406; TAF8_C; 1.
DR SMART; SM00576; BTP; 1.
DR SMART; SM00636; Glyco_18; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF54556; Chitinase insertion domain; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
DR PROSITE; PS01095; GH18_1; 1.
DR PROSITE; PS51910; GH18_2; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Initiation factor {ECO:0000313|EMBL:KYO34241.1};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein biosynthesis {ECO:0000313|EMBL:KYO34241.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 352..665
FT /note="GH18"
FT /evidence="ECO:0000259|PROSITE:PS51910"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 240..298
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 257..292
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 680 AA; 75156 MW; DCA8088B58F38B0B CRC64;
MRTAALEPKM ADTASGGSST RSCGKYATTP ADNYYLARRR TLQVVVSSLL TEAGFESAEK
AAVETLTEML QSYVSEIGRS AKSYCEHTAR TQPTLSDIVV TLVEMGFNVD TLPAYAKRSQ
RMVITAPPVT NQPVTPKALT AGQNKPHPSH IPSHFPEFPD PHTYIKTPTY REPVSDYQVL
REKAASQRRD VERALTRFMA KTGETQSLFK DDVSTFPLIA ARPFTIPYLT ALLPSELEMQ
QMEETDSSEQ DDQTDTENLP LHMSTDDSGT EKENASVLQQ NTSLSGSRNG EENMIDNPYL
RPVKKPKIRR KKFPAFHHGE VIKPTVIQLR EDPRADSSPW LEPSCEDLGA KGNKVCGFHA
DKGTSLCHIN QHGAPGRHLI GRKDEKRAAV DRLGRFAAVA AGNDKLVTLL AIGGWNFGTQ
KFTQMVASQA NRKTFIDSVI AYLRKFGFDG IDLDFEYPGS RGSPPEDKHR FTILIQEMLD
AFTAEAASAN KPRLLITAAV SAGKATIDAG YEIAAIGGLL DFISVMTYDF HGGWDPVTGH
NSPLYEGCKD QGDFKFFNCK YAMEYWKNNG APPEKLIMGF PTYGRTFRIS GTDHCVGAPA
SGAGSSGPYT REAGFWAYYE VQYLKENNFG GAMVWAIDLD DFLGTFCNEG KYPLISELKR
LLETNGSLVY DEICKCCNYP
//
