ID A0A151NHU5_ALLMI Unreviewed; 1992 AA.
AC A0A151NHU5;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Myosin-9 {ECO:0000256|ARBA:ARBA00039816};
DE AltName: Full=Myosin heavy chain 9 {ECO:0000256|ARBA:ARBA00041440};
DE AltName: Full=Myosin heavy chain, non-muscle IIa {ECO:0000256|ARBA:ARBA00042289};
DE AltName: Full=Non-muscle myosin heavy chain IIa {ECO:0000256|ARBA:ARBA00043098};
GN ORFNames=Y1Q_0024143 {ECO:0000313|EMBL:KYO36392.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO36392.1};
RN [1] {ECO:0000313|EMBL:KYO36392.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO36392.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, Cortical
CC granule {ECO:0000256|ARBA:ARBA00037865}.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO36392.1}.
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DR EMBL; AKHW03002956; KYO36392.1; -; Genomic_DNA.
DR STRING; 8496.A0A151NHU5; -.
DR eggNOG; KOG0161; Eukaryota.
DR PhylomeDB; A0A151NHU5; -.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
DR GO; GO:0060473; C:cortical granule; IEA:UniProtKB-SubCell.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.340; -; 5.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.30.70.1590; -; 1.
DR Gene3D; 6.10.250.2420; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 4.10.270.10; Myosin, subunit A; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR008989; Myosin_S1_N.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR PANTHER; PTHR45615:SF16; MYOSIN-9; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR Pfam; PF01576; Myosin_tail_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00015; IQ; 1.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 6.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Cell shape {ECO:0000256|ARBA:ARBA00022960};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000050525}.
FT DOMAIN 56..109
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 113..808
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 1..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 686..708
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1066..1088
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1723..1753
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1798..1821
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1915..1992
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1723..1742
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1798..1812
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1915..1940
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1947..1962
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1969..1992
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 206..213
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1992 AA; 229940 MW; B171EA7B8100F190 CRC64;
MGGACSSGRG GSTRLETSQC RCVRGRQADA ENESLPGQKQ PPPPRLSPAD RRTQVPQYKP
PWLREMSIKK NGFEAASIKE EAGDEAVVEL AENGKKIKVN KDDIQKMNPP KFSKVEDMAE
LTCLNEASVL HNLKERYYSG LIYTYSGLFC VVINPYKNLP IYSEEIVDMY KGKKRHEMPP
HIYAITDTAY RSMMQDREDQ SILCTGESGA GKTENTKKVI QYLAHVASSH KSKKDQGELE
RQLLQANPIL EAFGNAKTVK NDNSSRFGKF IRINFDVNGY IVGANIETYL LEKSRAIRQA
KEERTFHIFY YLLSGAGEHL KTDLLLEPYN KYRFLSNGHV TIPGQQDKDM FQETMEAMKI
MGIPDDEQMG LLKVISGVLQ LGNIAFKKER NTDQASMPDN TAAQKVSHLL GINVTDFTRG
ILTPRIKVGR DYVQKAQTKE QADFAIEALA KATYERMFRW LVMRINKALD KTKRQGASFI
GILDIAGFEI FELNSFEQLC INYTNEKLQQ LFNHTMFILE QEEYQREGIE WNFIDFGLDL
QPCIDLIEKP AGPPGILALL DEECWFPKAT DKSFVEKVMQ EQGSHPKFQK PKQLKDKADF
CIIHYAGKVD YKADEWLMKN MDPLNDNIAT LLHQSSDKFV SELWKDVDRI VGLDQVAGMS
ESALPGAFKT RKGMFRTVGQ LYKEQLAKLM ATLRNTNPNF VRCIIPNHEK KAGKLDPHLV
LDQLRCNGVL EGIRICRQGF PNRVVFQEFR QRYEILTPNS IPKGFMDGKQ ACVLMIKALE
LDPNLYRIGQ SKVFFRAGVL AHLEEERDLK ITDVIIGFQA CCRGYLARKA FAKRQQQLTA
MKVLQRNCAA YLKLRNWQWW RLFTKVKPLL QVSRQEEEMM AKEEELVKVK EKQLAAENRL
SEMETLQTQL MAEKMQLQEQ LQAETELCAE AEEIRARLTA KKQELEDICH DLEARVEEEE
ERCQHLQIEK KKMQQNIQEL EEQLEEEESA RQKLQLEKVT TEAKVKKLEE DLIVLEDHNL
KLGKEKKLLE DRISEFTTNL TEEEEKSKSL AKLKNKHEAM ITDLEERLRR EEKQRQELEK
TRRKLEGDSG DLHDQIAELQ AQIAELKMQL AKKEEELQAA LARVEEESSQ KNMALKKIRE
LESQITELQE DLESERAARN KAEKQKRDLG EELEALKTEL EDTLDSTAAQ QELRSKREQE
VTLLKKTLDD EAKTHEAQIQ EMRQKHAQVV EELAEQLEQT KRVKANLEKA KQTLESDRAE
LSNEVKVLLQ GKGDSEHKRK KVETQLQELQ VKFAEGERVR TELAEKVNKL QVELDNVTGL
LNQSDSKSIK LAKDFSTLES QLQDTQELLQ EETRQKLSLS TKLKQMEDEK NSIKEQLEEE
EEAKINLEKQ ISALHQQIAD MKKKVDDGLG CLEMVEEAKK KLQKDLEAMS QRYEEKAAAF
DKLEKTKTRL QQELDDLTVD LDHQRQIVSN LEKKQKKFDQ LLAEEKNISA KYAEERDRAE
AEAREKETKA LSLARALEEA MEQKAELERL NKQFRTEMED LMSSKDDVGK SVHELEKAKR
ALEQQVEEMK TQLEELEDEL QATEDAKLRL EVNQQAMKAQ FERDLQGRDE QNEEKRKQLI
RQVREMEVEL EDERKQRSIA VAARKKLEMD LKDLEGQIDS ANKNRDEAIK QLRKVQAQMK
DCMRELDDTR TSREEILAQA KENEKKMKNM EAEMIHMQEE LAAAERAKRQ AQQERDELAD
EIANSSGKGA LAMEEKRRLE ARIAQLEEEL EEEQGNTEMV NDRLKKANLQ VDQINADLNA
ERSNAQKNEN ARQQMERQNK ELKVKLQEME GIMKSKYKSN ITALEAKIAQ LEEQLDSETK
ERQAASKQVR RTEKKLKDIL LQVDDERRNA EQFKDQVDKS HVRLKQLKRQ LEEAEEEAQR
ANAARRKLQR ELEDATETAD AMNREVSSLK SKLRRGDLPF VVPRRMGRKG TGECSDEEVD
GKADAGDAKA TE
//
