ID A0A151P965_ALLMI Unreviewed; 670 AA.
AC A0A151P965;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Rhophilin-2 {ECO:0000313|EMBL:KYO45285.1};
GN Name=RHPN2 {ECO:0000313|EMBL:KYO45285.1};
GN ORFNames=Y1Q_0014725 {ECO:0000313|EMBL:KYO45285.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO45285.1};
RN [1] {ECO:0000313|EMBL:KYO45285.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO45285.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SIMILARITY: Belongs to the RHPN family.
CC {ECO:0000256|ARBA:ARBA00010369}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO45285.1}.
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DR EMBL; AKHW03000629; KYO45285.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151P965; -.
DR STRING; 8496.A0A151P965; -.
DR eggNOG; KOG2220; Eukaryota.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd09248; BRO1_Rhophilin_1; 1.
DR CDD; cd11633; HR1_Rhophilin-1; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 1.25.40.280; alix/aip1 like domains; 1.
DR Gene3D; 1.10.287.160; HR1 repeat; 1.
DR InterPro; IPR004328; BRO1_dom.
DR InterPro; IPR038499; BRO1_sf.
DR InterPro; IPR011072; HR1_rho-bd.
DR InterPro; IPR036274; HR1_rpt_sf.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR042715; Rhophilin-1_BRO1.
DR InterPro; IPR047138; RHPN1_2.
DR PANTHER; PTHR23031; RHOPHILIN; 1.
DR PANTHER; PTHR23031:SF6; RHOPHILIN-1; 1.
DR Pfam; PF03097; BRO1; 1.
DR Pfam; PF02185; HR1; 1.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM01041; BRO1; 1.
DR SMART; SM00742; Hr1; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF46585; HR1 repeat; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS51180; BRO1; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS51860; REM_1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01207};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525}.
FT DOMAIN 32..106
FT /note="REM-1"
FT /evidence="ECO:0000259|PROSITE:PS51860"
FT DOMAIN 117..466
FT /note="BRO1"
FT /evidence="ECO:0000259|PROSITE:PS51180"
FT DOMAIN 522..589
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 670 AA; 75475 MW; 5E5A8A2937C6FDB5 CRC64;
MLIPEEEEES RGAGGHLVRQ PPDTGSVRKG CDPFAQTQRS KLQHRRARIN QQINKEMRMR
AGAENLFRAT SNHKVKETVA LELSYVNSNL QLLKEELEEL NSCMDVYQND SEAISVPMIP
LGLKETKELD LMVPLRDFIC EHYGEDGALF DKEIREFMEL RQAMRTPSRN EAGLELLMEY
YNQLYFLDNR FFPPSKNLGV FFHWYDSLTG VPSHQRALAF EKGSVLFNIG ALHTQIGARQ
DRTTLQGVDR AIDAFQKAAG AFNYLKENFS NAPSLDMSAP SLNMLVHLMI AQVQECVFEK
VTLIHAQDDF LTQLQIAQEA ARVEDVYSLV HQTMTQAHVK GYVPFSWTTM VHVKSEHFEA
LSHYYTAIAL CDCPVASDAD LPEHEKVFIQ FHVTMPEGPS LRVLLQDQEE RRKLGKAHLK
KAIMRHEEAM RIHGLCKILR KMDILQEVLS FAHKRSLSKY SDIDHEEDFF ETGDAPDIHP
KTHQRPEIKS PNFSQAKVTD IFHRLGPLTV FSAKNKWHPA RKVHLVRGES GFGFTLRGDS
PVLIAGVISG GCAAEAGLKE GDFIVSVNGK DCRWSKHAEV VQLLKSVGED GVELSVITLQ
SSEVQNMVDR KSAAMSSGGG LLKNNKENSR KSLMNSKSAS TLLAWKKSKR SKNSTYSLPF
AAVGDNEATY
//
