ID A0A151PFN2_ALLMI Unreviewed; 2206 AA.
AC A0A151PFN2;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 03-MAY-2023, entry version 24.
DE RecName: Full=Calponin-homology (CH) domain-containing protein {ECO:0000259|PROSITE:PS50021};
GN ORFNames=Y1Q_0019864 {ECO:0000313|EMBL:KYO47809.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO47809.1};
RN [1] {ECO:0000313|EMBL:KYO47809.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO47809.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SIMILARITY: Belongs to the Nav/unc-53 family.
CC {ECO:0000256|ARBA:ARBA00006255}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO47809.1}.
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DR EMBL; AKHW03000416; KYO47809.1; -; Genomic_DNA.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0022008; P:neurogenesis; IEA:InterPro.
DR CDD; cd21286; CH_NAV3; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR039041; Nav/unc-53.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR12784:SF18; NEURON NAVIGATOR 3; 1.
DR PANTHER; PTHR12784; STEERIN; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF00307; CH; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00033; CH; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50021; CH; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525}.
FT DOMAIN 27..134
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REGION 154..502
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 647..666
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 774..1228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1262..1321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1515..1600
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1671..1702
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2182..2206
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1414..1497
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 154..198
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 207..239
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 251..317
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 347..361
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 378..393
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 411..445
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 475..502
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 776..820
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 821..856
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 872..913
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 929..943
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 974..995
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1005..1094
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1108..1131
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1166..1228
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1300..1321
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1519..1538
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1575..1589
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1681..1702
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2206 AA; 237693 MW; D20D20CB0719E4B9 CRC64;
MLSCQLTLKS TCNFEEKKTL QGKSKEIEDS KIYTDWANHY LAKSGHKRLI KDLQQDIADG
VLLAEIIQII ANEKVEDINV CPRSQSQMIE NVDVCLSFLA ARGVNVQGLS AEEIRNGNLK
AILGLFFSLS RYKQQQHHQQ QYYQSLVELQ QQVSHSSPPG EISQLKTQQD MQSSLTARYA
TQSNHSGIAT SQKKTSRLPG PSRVPAAGSS TKVQGASNLN RRSQSFNSID KNKPPQYANG
NDKDSPKGPH PSTGMNGNVQ HPTSTGQQQV SAIPSPSASK PWRSKSMNVK HSATSTMLSV
KQPSPATSPT PSSDRLKPPL SEGTKPPSSG QKSMLEKFKL VNARTALRPP LSSSSGPSDS
GREDDAFSEC GEIDGLSSGL NSGGSTSSSP KVSPKLAPPK AGSKNLSNKK SLLQPKDKEE
KNRDKNKVCT EKTVKEEKDQ TTETSTKKSS KIASLIPKGS KTAAAKKESL IPSSSGIPKP
GSKVPTAKQS ASPTCAGMAA SSGQVTGNGI VQLPQQQQYS HPNTATVAPF IYRTLSENDS
TSLPPAESCT SPTKMDLSYS KTAKQCLEEI SGEDPETRRM RTVKNIADLR QNLEETMSSL
RGTQISHSTL ETTFDSTVTT EVNGRSLPSL TSRSTPVTWR LGQASPRLQA GDAPSLGGGY
PRSSTSRFIH TDPSRFMYTT PLRRAAVSRL GNMSQIDLNE KGSGDLDMSS EVDVGGYMSD
GDILGKSLRT DDINSGYMTD GGLNLYTRSL NRIPDLAASR DVIQRGVHDV TVDADSWDDS
SSVSSGLSDT LDNLSTDDLN TTSSVSSYSN ITASSRKNAH TQLKTDSEKR SATDSETWGS
TDELKKPEED FDSSIDGSGK WKGLPSGLSE DSEKGGQKSS LSVSQTGSWR RGMTAQVGTT
PSRHKTGTSA LKTPGKTDDA KASEKVKSPL KGSSIQRSPS DAGKSSGDEG KKPPSGIGRS
TATGSFGFKK AGVGSSTIIT TSGATITSGS ATLGKIPKSS AIGGKSNAGR KTSLDGSQNQ
DDGVLHVSSK TTLQYRSLPR PSKSSTSGIP GRGGHRSSTS SIDSNVSSKS AGTATTKLRE
PTKIGSGRSS PVTINQTDKE KEKVAVSDSE SVSLSSSPKS SPTSASACGT PGLRQPGSKY
PDIASPTFRR LFGAKASGKA ASAPSPEGVK STSAMPSPST TLARQGSLES PSSGGLVWAA
NMSSSSAGSK DTPSYQSMTS LHTSSESIDL PLSHHGSLSG LTTGTQEVQS LLMRTGSVRS
TLSESMQLDR NTLPKKGLRY TPSSRQTSQE EGKEWLRSHS TGGLQDTGSQ SPLVSPSAMS
SSTTGKYHFS NLVSPTNLSQ FNLPGPSMMR SNSIPAQDTS FDLYDDSQLC GSATSLEERP
RAISHSGSFR DSMEEDDIQI IAVLAFGHIV QAEEKAHSEQ IQKLRRELVA SQEKVATLTS
QLSANAHLVA AFEKSLGNMT GRLQSLTMTA EQKESELIEL RETIEMLKAQ NSAAQAAIQG
ALNGPDHTHK DLRIRRQHSS ESVSSINSAT SHSSIGSGND ADSKKKKKKN WLRSSFKQAF
GKKKSTKPPS SHSDIEELTD SSLPSSPKLP HSSGECGAAA MKPSQSASAI CECTEAEAEI
ILQLKSELRE KELKLTDIRL EALSSAHHLD QIREAMNRMQ NEIEILKAEN DRLKAETGNT
GKPARPSSES SSSTSSSSSR QSLGLSLNNL NITDPITSDI LLEDIADGGL HKEGHSVKIL
VTINKGYGRA KDQKMQAYLI GSIGVSGKTK WDILDGVIRR LFKEYIFRVD PSTSLGLSSD
CIASYCIGDI IRAHSLEVPE LLPCGYLVGD NNIISVNLKG VEENSLDSFV FDTLIPKPIT
QRYFNLLMEH RRIILSGPSG TGKTYLANRL AEYVITKSGR KKLEDAIATF NVDHKSSKDL
RQYLANLAEQ CSADNSGADL PLVIILDNLH HIGSLSDIFN GFLNCKYNKC PYIIGTMNQG
VSSSPNLELH HNFRWVLCAN HTEPVKGFLG RYLRRKLIET EIEKNMRNND LIKIIDWIPK
TWHHLNSFLE THSSSDVTIG PRLFLPCPMD VDGSRVWFTD LWNYSLVPYL LEAVREGLQM
YGKRAPWEDP SKWVADTYPW SSASLQHDWP SLLQLRPEDV GYEGYAFAKE GTTSKHIPQS
DTEGDPLMNM LMRLQEAANY SSAQSCDSDS TSHHDDILDS SLESTL
//
