ID   A0A151WJA6_9HYME        Unreviewed;      1132 AA.
AC   A0A151WJA6;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=Alpha-mannosidase {ECO:0000256|RuleBase:RU361199};
DE            EC=3.2.1.- {ECO:0000256|RuleBase:RU361199};
GN   ORFNames=ALC60_13051 {ECO:0000313|EMBL:KYQ47914.1};
OS   Trachymyrmex zeteki.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Myrmicinae; Trachymyrmex.
OX   NCBI_TaxID=64791 {ECO:0000313|EMBL:KYQ47914.1, ECO:0000313|Proteomes:UP000075809};
RN   [1] {ECO:0000313|EMBL:KYQ47914.1, ECO:0000313|Proteomes:UP000075809}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tzet28-1 {ECO:0000313|EMBL:KYQ47914.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:KYQ47914.1};
RA   Nygaard S., Hu H., Boomsma J., Zhang G.;
RT   "Trachymyrmex zeteki WGS genome.";
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|RuleBase:RU361199};
CC       Note=Binds 1 zinc ion per subunit. {ECO:0000256|RuleBase:RU361199};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC       {ECO:0000256|ARBA:ARBA00009792, ECO:0000256|RuleBase:RU361199}.
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DR   EMBL; KQ983043; KYQ47914.1; -; Genomic_DNA.
DR   RefSeq; XP_018314083.1; XM_018458581.1.
DR   AlphaFoldDB; A0A151WJA6; -.
DR   STRING; 64791.A0A151WJA6; -.
DR   GeneID; 108729453; -.
DR   OrthoDB; 5474711at2759; -.
DR   Proteomes; UP000075809; Unassembled WGS sequence.
DR   GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR   CDD; cd10809; GH38N_AMII_GMII_SfManIII_like; 1.
DR   Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR   Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR   InterPro; IPR011682; Glyco_hydro_38_C.
DR   InterPro; IPR015341; Glyco_hydro_38_cen.
DR   InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR   InterPro; IPR000602; Glyco_hydro_38_N.
DR   InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR   InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   PANTHER; PTHR11607; ALPHA-MANNOSIDASE; 1.
DR   PANTHER; PTHR11607:SF3; LYSOSOMAL ALPHA-MANNOSIDASE; 1.
DR   Pfam; PF09261; Alpha-mann_mid; 1.
DR   Pfam; PF07748; Glyco_hydro_38C; 1.
DR   Pfam; PF01074; Glyco_hydro_38N; 1.
DR   SMART; SM00872; Alpha-mann_mid; 1.
DR   SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR   SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361199};
KW   Hydrolase {ECO:0000256|RuleBase:RU361199};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU361199};
KW   Reference proteome {ECO:0000313|Proteomes:UP000075809};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361199}.
FT   DOMAIN          486..568
FT                   /note="Glycoside hydrolase family 38 central"
FT                   /evidence="ECO:0000259|SMART:SM00872"
SQ   SEQUENCE   1132 AA;  129515 MW;  CAE8BD3DAB909858 CRC64;
     MRTRKTIAIL GAGLTLACCA MTYLMMDLTL LSPGQGPKLS MSNNQWLHLE NRLAKLEKDF
     DKHHKVMNAL QEQAAKIKNN FVPIIQPSHF NHSNIKNSRL EKSLTCNFNI QKVPKVDIQM
     LELYKQLEFD NPDGGVWKQG WNIMYDEKQW HPNKKLKVFV VPHSHNDPGW LNTFEKYYMF
     QTRSILNNMV TKLGEDRRRK FIWAEISFFK LWWDDQSKEI KDEVRRLIHD GQLEIVSGGW
     VMPDESVSHW IAQLTQLTEG HQWLKYNLDY TPNSGWAIDP FGLSPTMPYL LKNSGLENLL
     IQRVHYSVKK KLAKDKNLEF RWRQLWDDDG STEFLTHIMP FYSYDVPHTC GPDPKVCCQF
     DFYRMQNFGL SCPWKIPPKT ITRANVAERA LLLLDQYRKK AQLFKTNVVL APLGDDFRYT
     HLTEWEAQYD NYQKLFNYMN ENQHLNVQIQ FGTLSDYFEA IREKHNFNEF PTLSGDFFTY
     SDRDDHYWSG YYTSRPFHKR LDRVLLGSLR GSEALAAIAW ARSNDQLVEG NLASRLSKAR
     MWHSLFQHHD GVTGTARDNV VIDYAQKMIM ALNNSAHVLQ QSIAHLLRTP QISPMDVEAV
     YFSLDETRSH HTSVGEKHVL NLGDDKPSRK IILYNSLPRQ RTKVQTLIVS TPFVRVTDRS
     GQTVKCQVSP IWIGPAALST ARYELSFLVT VPGFGITTYI VHTLHKASYT KEVYLANVTI
     FNTDINFPSI PGFNHLTILS HSQEFSISQR PNLSASFGKS GLLKALRVDN TMFPVHLDFV
     KYGTRSSGKD RSGAYLFLPD KSEPDVVFMD GRAIIHLVTG PILSKVFIEL PYVRHTCTLF
     NSPGSDGLGL HIFNEVDITE TQNYELAMRF NTDIASGNQF FTDLNGLNII RRQRFSKLPT
     QGNYYPMAAS TYIEDKRVRL TVATAQPLGV ASMASGQLEI MQDRRLLQDD NRGLGQGVMD
     NLLTNHIFTL ILEKKETNCP FAVPTNHPAG LLSLSGHLAS EELLHPIVVL HPHNSLPFNL
     HAYFSPLRYD LPVDLSIVSL RAFPIPEGAG KGIGMVLHQS ALDTCFNNSF LRHFNVSESG
     EVDLTKLFND MEDWTISKAP LTFHNVGPSL KSPIVNLCPH QILPILFHKT QS
//