ID   A0A151WQN2_9HYME        Unreviewed;       698 AA.
AC   A0A151WQN2;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Phenoloxidase subunit A3 {ECO:0000313|EMBL:KYQ50113.1};
GN   ORFNames=ALC60_10806 {ECO:0000313|EMBL:KYQ50113.1};
OS   Trachymyrmex zeteki.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Myrmicinae; Trachymyrmex.
OX   NCBI_TaxID=64791 {ECO:0000313|EMBL:KYQ50113.1, ECO:0000313|Proteomes:UP000075809};
RN   [1] {ECO:0000313|EMBL:KYQ50113.1, ECO:0000313|Proteomes:UP000075809}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tzet28-1 {ECO:0000313|EMBL:KYQ50113.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:KYQ50113.1};
RA   Nygaard S., Hu H., Boomsma J., Zhang G.;
RT   "Trachymyrmex zeteki WGS genome.";
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Cu(2+); Xref=ChEBI:CHEBI:29036;
CC         Evidence={ECO:0000256|ARBA:ARBA00001973};
CC   -!- SIMILARITY: Belongs to the tyrosinase family.
CC       {ECO:0000256|ARBA:ARBA00009928}.
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DR   EMBL; KQ982829; KYQ50113.1; -; Genomic_DNA.
DR   RefSeq; XP_018311127.1; XM_018455625.1.
DR   AlphaFoldDB; A0A151WQN2; -.
DR   STRING; 64791.A0A151WQN2; -.
DR   GeneID; 108727483; -.
DR   OrthoDB; 5406463at2759; -.
DR   Proteomes; UP000075809; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0004503; F:tyrosinase activity; IEA:UniProt.
DR   GO; GO:0006582; P:melanin metabolic process; IEA:UniProt.
DR   GO; GO:1901564; P:organonitrogen compound metabolic process; IEA:UniProt.
DR   Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR   Gene3D; 2.60.40.1520; Hemocyanin, C-terminal domain; 1.
DR   Gene3D; 1.20.1370.10; Hemocyanin, N-terminal domain; 1.
DR   InterPro; IPR008922; Di-copper_centre_dom_sf.
DR   InterPro; IPR013788; Hemocyanin/hexamerin.
DR   InterPro; IPR000896; Hemocyanin/hexamerin_mid_dom.
DR   InterPro; IPR005203; Hemocyanin_C.
DR   InterPro; IPR037020; Hemocyanin_C_sf.
DR   InterPro; IPR005204; Hemocyanin_N.
DR   InterPro; IPR036697; Hemocyanin_N_sf.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR002227; Tyrosinase_Cu-bd.
DR   PANTHER; PTHR11511; LARVAL STORAGE PROTEIN/PHENOLOXIDASE; 1.
DR   PANTHER; PTHR11511:SF4; PHENOLOXIDASE 2-RELATED; 1.
DR   Pfam; PF03723; Hemocyanin_C; 1.
DR   Pfam; PF00372; Hemocyanin_M; 1.
DR   Pfam; PF03722; Hemocyanin_N; 1.
DR   PRINTS; PR00187; HAEMOCYANIN.
DR   SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR   SUPFAM; SSF81296; E set domains; 1.
DR   SUPFAM; SSF48050; Hemocyanin, N-terminal domain; 1.
DR   PROSITE; PS00209; HEMOCYANIN_1; 1.
DR   PROSITE; PS00210; HEMOCYANIN_2; 1.
DR   PROSITE; PS00498; TYROSINASE_2; 1.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Monooxygenase {ECO:0000256|ARBA:ARBA00023033};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000075809};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT   DOMAIN          397..408
FT                   /note="Tyrosinase copper-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00498"
SQ   SEQUENCE   698 AA;  80199 MW;  367384E8FC3A7256 CRC64;
     MGSKKSDILY LFDRPAEPVY VPKGENKVAF DVPANYLPES RQQMAPAIVN RFADDTSSKV
     PVKQISLPDL SVPLQLGRRE PFSLFIPKHR KLAARLIDIF LGMQTFDDFL SVAVYCRDRV
     NPEMFVYVLS VAILNRPDTK DLPIPPLSEI FPDKYIDSGI FARAREEANV VPAGSREPIE
     IPRDYTASDL DEEHRVAYWR EDIGINLHHW HWHLVYPAEA DIKIVKKDRR GELFYYMHHQ
     IQSRYNAERL SNRLGRVKRF LNWRESIPEG YFPKLVAGSL NIWPARPASA VLKDINRPVD
     QLYFDIQDLE RWRDRIYEAI HTGVYISPCG ERKPLTEFDG IDMLGNIIEA SILSPNQNIY
     GDLHNLCHMA ISCCHDPDHR YLEPFSIMGS SATAMRDPIF YRLHGFIDHV FLEHKNTLPE
     YDLQQLSFPG VIITDIAVQT PNQPANQIST FWTKSDVDLS RGLDFTPRGP VLARFTHLNH
     TDFTYRIVAD NRNNAPRRGT VRIFIAPKQD ERGLPFVFRD QKELMIEMDK FTVLLKPGTN
     IIERKSTESS VTIPFESTFR NLDVNKPIGG DNLEQSNFCG CGWPQYMLVP KGKEEGFRMD
     LFIMISDYTG DAVEQDEPTG CKDAASFCGL RDRKYPDARP MGFPFDRRVR TDVRTLSDFL
     ISNMAVTQIN ILHTDTILPR MRSENMSDTL TKSAKSDD
//