ID A0A157STX3_9BORD Unreviewed; 343 AA.
AC A0A157STX3;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=UDP-glucose 4-epimerase {ECO:0000256|ARBA:ARBA00018569};
DE EC=5.1.3.2 {ECO:0000256|ARBA:ARBA00013189};
DE AltName: Full=UDP-galactose 4-epimerase {ECO:0000256|ARBA:ARBA00031367};
GN Name=capD {ECO:0000313|EMBL:SAI73887.1};
GN ORFNames=SAMEA3906486_04905 {ECO:0000313|EMBL:SAI73887.1};
OS Bordetella ansorpii.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Bordetella.
OX NCBI_TaxID=288768 {ECO:0000313|EMBL:SAI73887.1, ECO:0000313|Proteomes:UP000076848};
RN [1] {ECO:0000313|EMBL:SAI73887.1, ECO:0000313|Proteomes:UP000076848}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H050680373 {ECO:0000313|EMBL:SAI73887.1,
RC ECO:0000313|Proteomes:UP000076848};
RG Pathogen Informatics;
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=UDP-alpha-D-glucose = UDP-alpha-D-galactose;
CC Xref=Rhea:RHEA:22168, ChEBI:CHEBI:58885, ChEBI:CHEBI:66914;
CC EC=5.1.3.2; Evidence={ECO:0000256|ARBA:ARBA00000083};
CC -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC {ECO:0000256|ARBA:ARBA00007430}.
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DR EMBL; FKIF01000009; SAI73887.1; -; Genomic_DNA.
DR RefSeq; WP_066132951.1; NZ_FKIF01000009.1.
DR AlphaFoldDB; A0A157STX3; -.
DR STRING; 288768.SAMEA3906486_04905; -.
DR OrthoDB; 9769113at2; -.
DR Proteomes; UP000076848; Unassembled WGS sequence.
DR GO; GO:0003978; F:UDP-glucose 4-epimerase activity; IEA:UniProtKB-EC.
DR GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:InterPro.
DR CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013692; CapD_C.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003869; Polysac_CapD-like.
DR PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR PANTHER; PTHR43318:SF2; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE (INVERTING); 1.
DR Pfam; PF08485; Polysacc_syn_2C; 1.
DR Pfam; PF02719; Polysacc_synt_2; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000313|EMBL:SAI73887.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000076848}.
FT DOMAIN 7..281
FT /note="Polysaccharide biosynthesis protein CapD-like"
FT /evidence="ECO:0000259|Pfam:PF02719"
FT DOMAIN 284..330
FT /note="UDP-glucose 4-epimerase CapD C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08485"
SQ SEQUENCE 343 AA; 38322 MW; 00016F8D0D6BA1F3 CRC64;
MLTGKTLMIT GGTGSFGQAV LRRFLDADVR EIRVFSRDEK KQDDLRKRYA HSRLKFYIGD
VRDYASVSNA LRGVDFLFHA AALKQVPSCE FHPMEAVKTN VLGTENVLEA SIANGVGRVV
CLSTDKAVYP INAMGTSKAM MEKVMVAKSR HLDGATTICG TRYGNVMASR GSVIPLFVQQ
IRQGKPITIT DPSMTRFMMT LEDAVELVLY AFTHGGNGDI FVQKAPAATV GVLARAISEL
MECPDHPIDV IGTRHGEKLY EALLSREECV SARDEGRYFR VPPDLRDLNY SKFVEQGERR
ISMAEDYNSH NTQRLDLDGM KQLLLQLPFM HSVLRREPVL LED
//
