ID A0A158NZ41_ATTCE Unreviewed; 1211 AA.
AC A0A158NZ41;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Poly [ADP-ribose] polymerase {ECO:0000256|RuleBase:RU362114};
DE Short=PARP {ECO:0000256|RuleBase:RU362114};
DE EC=2.4.2.- {ECO:0000256|RuleBase:RU362114};
GN Name=105626095 {ECO:0000313|EnsemblMetazoa:XP_012062799.1};
OS Atta cephalotes (Leafcutter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Atta.
OX NCBI_TaxID=12957 {ECO:0000313|EnsemblMetazoa:XP_012062799.1, ECO:0000313|Proteomes:UP000005205};
RN [1] {ECO:0000313|Proteomes:UP000005205}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21347285; DOI=10.1371/journal.pgen.1002007;
RA Suen G., Teiling C., Li L., Holt C., Abouheif E., Bornberg-Bauer E.,
RA Bouffard P., Caldera E.J., Cash E., Cavanaugh A., Denas O., Elhaik E.,
RA Fave M.J., Gadau J., Gibson J.D., Graur D., Grubbs K.J., Hagen D.E.,
RA Harkins T.T., Helmkampf M., Hu H., Johnson B.R., Kim J., Marsh S.E.,
RA Moeller J.A., Munoz-Torres M.C., Murphy M.C., Naughton M.C., Nigam S.,
RA Overson R., Rajakumar R., Reese J.T., Scott J.J., Smith C.R., Tao S.,
RA Tsutsui N.D., Viljakainen L., Wissler L., Yandell M.D., Zimmer F.,
RA Taylor J., Slater S.C., Clifton S.W., Warren W.C., Elsik C.G., Smith C.D.,
RA Weinstock G.M., Gerardo N.M., Currie C.R.;
RT "The genome sequence of the leaf-cutter ant Atta cephalotes reveals
RT insights into its obligate symbiotic lifestyle.";
RL PLoS Genet. 7:e1002007-e1002007(2011).
RN [2] {ECO:0000313|EnsemblMetazoa:XP_012062799.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (APR-2016) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ADTU01000870; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01000871; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012062799.1; XM_012207409.1.
DR AlphaFoldDB; A0A158NZ41; -.
DR STRING; 12957.A0A158NZ41; -.
DR EnsemblMetazoa; XM_012207409.1; XP_012062799.1; LOC105626095.
DR GeneID; 105626095; -.
DR KEGG; acep:105626095; -.
DR eggNOG; KOG4177; Eukaryota.
DR InParanoid; A0A158NZ41; -.
DR OrthoDB; 5477658at2759; -.
DR Proteomes; UP000005205; Unassembled WGS sequence.
DR GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR CDD; cd09524; SAM_tankyrase1_2; 1.
DR CDD; cd01438; tankyrase_like; 1.
DR Gene3D; 3.90.228.10; -; 1.
DR Gene3D; 6.20.320.10; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 5.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR012317; Poly(ADP-ribose)pol_cat_dom.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR24178:SF9; ANK_REP_REGION DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24178; MOLTING PROTEIN MLT-4; 1.
DR Pfam; PF00023; Ank; 3.
DR Pfam; PF12796; Ank_2; 5.
DR Pfam; PF00644; PARP; 1.
DR Pfam; PF07647; SAM_2; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 17.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF56399; ADP-ribosylation; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 3.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 13.
DR PROSITE; PS50088; ANK_REPEAT; 14.
DR PROSITE; PS51059; PARP_CATALYTIC; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Glycosyltransferase {ECO:0000256|RuleBase:RU362114};
KW NAD {ECO:0000256|RuleBase:RU362114};
KW Reference proteome {ECO:0000313|Proteomes:UP000005205};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|RuleBase:RU362114}.
FT REPEAT 63..95
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 96..128
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 129..161
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 216..248
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 249..281
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 285..314
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 369..404
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 405..437
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 532..564
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 565..597
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 598..630
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 685..717
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 718..750
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 751..783
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 895..958
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 978..1202
FT /note="PARP catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51059"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1037..1056
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1211 AA; 131201 MW; 53EBFB2E0652D838 CRC64;
MAGRRSTLSN AADSLPGSGG GGGGGNGGDP LRELFEACKT GDLAKVKALV NPKTVNARDT
AGRKSTPLHF AAGYGRKDVV EFLLSAGASI QARDDGGLHP LHNACSFGHC DVVRLLLEAG
ASPNTRDNWN FTPLHEAAIK GKIDVCITLL QHGADVNIRN TEGKTALEVA DVSTKPVLTG
EYRKDELLEA ARSGNEERLL QLLNPLNVNC HASDGRRSTP LHLAAGYNRS RVVQILLQNG
ADVHAKDKGG LVPLHNACSY GHFEVTEALL KHGAAVNASD LWTFTPLHEA ASKSRAEVCS
LLLSEGADPT QLNCHSKSAI DVAPTLELQE RLAYEYKGHC LLDACRQADL TKLKKYLSQE
IVNFKHPYTG DTPMHCAVAS PYPKRKQVIE ALIRKNAAMN EKNKDFLTPL HVATDHSHYD
AMDILLRHNA KVNALDGLGQ TALHRCARED NVQACRILLS YNIDPSIISL QGYTAAQISA
ENVLKILQDP PNGTDDVEAQ LLEASKSGDL AAVERILQAN PHAVNCRDLD GRHSTPLHFA
AGFNRVPVVE YLLAHGADVH AKDKGGLVPL HNACSYGHYE VTELLVKHGA SVNVADLWKF
TPLHEAAAKG KYEIVRLLLR HGADATKKNR DGATPLDLVR DGDQDVADLL RGNSALLDAA
KKGNLARVQR LVTQDNINCR DAQGRNSTPL HLAAGYNNLE VAEFLLERGA DVNAQDKGGL
IPLHNASSYG HLDIAALLIK YNTVVNATDK WGFTPLHEAA QKGRTQLCAL LLAHGADPFL
KNQEGQTPVD LASADDVRCL LQDAMASQQI VPTVPSGNMV NSSGGNSINS RPPSIVSVPV
TPPPPLTQET VIMPSGAAMT LCVPLARPTS CLSPMPPSEP CSEKESKDIC KEHNSTITTV
AGFLQSLGLE HLLELFEREQ ITLDILAEMG HEDLKQVGVS AYGYRHKLIK GMDKLLNTAA
GSLWQPSINP GTLLVDLLTE DKEFLAVEEE MQSTIRQHRD NGHSGGIFSR YNIVRIQKVQ
NRKLWERYAH RRQEVAEEVG AAAPASPSTG PRGVASSTVS QANERMLFHG SPFINAIVQK
GFDERHAYIG GMFGAGIYFA EHSSKSNQYV YGICGGTGCP AHKDRSCYIC HRHLLLCRVT
LGKSFLQFSA MKMAHAPPGH HSVMGRPSQG GLVFPEYVVY RGEQAYPEYL ITYQIARPQQ
ESGGSDGVEE R
//
