ID A0A158PQ48_BRUPA Unreviewed; 843 AA.
AC A0A158PQ48;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=C2 domain-containing protein {ECO:0000313|WBParaSite:BPAG_0000096201-mRNA-1};
GN ORFNames=BPAG_LOCUS963 {ECO:0000313|EMBL:VDN82149.1};
OS Brugia pahangi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6280 {ECO:0000313|Proteomes:UP000038020, ECO:0000313|WBParaSite:BPAG_0000096201-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:BPAG_0000096201-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN82149.1, ECO:0000313|Proteomes:UP000278627}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UZAD01000058; VDN82149.1; -; Genomic_DNA.
DR STRING; 6280.A0A158PQ48; -.
DR WBParaSite; BPAG_0000096201-mRNA-1; BPAG_0000096201-mRNA-1; BPAG_0000096201.
DR Proteomes; UP000038020; Unplaced.
DR Proteomes; UP000278627; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd20831; C1_dGM13116p-like; 1.
DR Gene3D; 3.30.60.20; -; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR InterPro; IPR046349; C1-like_sf.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR039934; C2CD2/C2CD2L.
DR InterPro; IPR002219; PE/DAG-bd.
DR PANTHER; PTHR21119:SF5; C2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR21119; UNCHARACTERIZED; 1.
DR Pfam; PF00130; C1_1; 1.
DR Pfam; PF00168; C2; 1.
DR SMART; SM00109; C1; 1.
DR SMART; SM00239; C2; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000278627};
KW Signal {ECO:0000256|SAM:SignalP}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..843
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041120673"
FT DOMAIN 279..418
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 781..833
FT /note="Phorbol-ester/DAG-type"
FT /evidence="ECO:0000259|PROSITE:PS50081"
FT REGION 635..727
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 635..675
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 707..727
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 843 AA; 95569 MW; 54C2FF8A22AC9129 CRC64;
MDGLTWLIMS WLIVGILCYF MLAKVGTSQT TVTTGINDTT IKSRATSSKW INDQYSIDWL
NDIIGWLFNN MHRVPDTLQA WIIAMNEAAK KISIPGKFEV LFEGFSDNRN VTRAPRVTDI
RLQQSPNDHL VGPIMKGKIS IPEVNLKLMS SQRTGDRLLV TSFDAKIIDL HGEIELHLAC
IANQIYMMAC FCGRPELDIE LVNRDPAPTG TVSNTMVDEM IRKCLLSAVT NVSLTEPGGQ
CGRMATNNVF AIIPRAMTTN IGGSETFDRT DNLATVPTHE MMKRINQSTV PQTVSNKMRV
NVIRAQRLGG DRRHFFKAIN QSYVVLEMDE PAQKFQTKYG LNISPYWEES FDFDLTPASE
EILFEIYEGS SSDTSFNAPT EYVGYSGQKE HEDHRFLGLA IVSLDEVRHS SANILHTLKL
QGRPYRNDII TGNLTVQFDF YYDPMGNSIG KNLDQTIVRN SANQFREIVN SSTTRPVYDP
RDSFGAYDNH DMTTTNTTTV TVKNVSQQSL NDKSQPLVSG ITTVQQTSTT PMAYDSLYEQ
RIDVSDMQQQ QHSYDITVQQ QSSGLNERQG YQQASNATTV GMQEHVIPGS STTSIQHFIT
GTKDRHIIDT DNYPYYRYDE QEAEVLIKTE AEEVSQTKEI NEMRQSRDQV KTRSEEKTVR
KRDRSFFNEL RERLSGRRRS KRRAKSCEPG GGDMEETVSL PPSRDISRTR FSEKSGSRHD
LGSSCDKSEH SIKSLYQHST LLLETHENGQ KRYYLIPHAV LDEPGATKLL RQGKKLHVHN
GHTFVAVKSR SGTTCNVCHQ RIGRSNFTKQ AYQCRDCYTV CHKPCHYKTE SYCTTSNVDK
LNM
//
