ID   A0A158QB26_ENTVE        Unreviewed;       935 AA.
AC   A0A158QB26;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   SubName: Full=WD_REPEATS_REGION domain-containing protein {ECO:0000313|WBParaSite:EVEC_0000798801-mRNA-1};
GN   ORFNames=EVEC_LOCUS7472 {ECO:0000313|EMBL:VDD92721.1};
OS   Enterobius vermicularis (Human pinworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Enterobius.
OX   NCBI_TaxID=51028 {ECO:0000313|Proteomes:UP000038041, ECO:0000313|WBParaSite:EVEC_0000798801-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:EVEC_0000798801-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (APR-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDD92721.1, ECO:0000313|Proteomes:UP000274131}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the WD repeat WDR3/UTP12 family.
CC       {ECO:0000256|ARBA:ARBA00038229}.
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DR   EMBL; UXUI01008937; VDD92721.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A158QB26; -.
DR   STRING; 51028.A0A158QB26; -.
DR   WBParaSite; EVEC_0000798801-mRNA-1; EVEC_0000798801-mRNA-1; EVEC_0000798801.
DR   Proteomes; UP000038041; Unplaced.
DR   Proteomes; UP000274131; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProt.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProt.
DR   CDD; cd00200; WD40; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR007148; SSU_processome_Utp12.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR19853; WD REPEAT CONTAINING PROTEIN 3 WDR3; 1.
DR   PANTHER; PTHR19853:SF0; WD REPEAT-CONTAINING PROTEIN 3; 1.
DR   Pfam; PF04003; Utp12; 1.
DR   Pfam; PF00400; WD40; 7.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 12.
DR   SUPFAM; SSF50978; WD40 repeat-like; 2.
DR   PROSITE; PS00678; WD_REPEATS_1; 3.
DR   PROSITE; PS50082; WD_REPEATS_2; 5.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000274131};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW   ProRule:PRU00221}.
FT   REPEAT          45..77
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          89..122
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          131..172
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          585..616
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          674..715
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   DOMAIN          799..900
FT                   /note="Small-subunit processome Utp12"
FT                   /evidence="ECO:0000259|Pfam:PF04003"
SQ   SEQUENCE   935 AA;  105289 MW;  EF2D4BA673DC0738 CRC64;
     MGITKQYLRY SLSGVCNIIG SNNGMLAAVN GNVCAVSACE NIKELKNSEK AVTAIKFSHD
     KRYLAVGYSD GTLKLFDRSS EDDSPFVTFV GHKTGVNCLA FSLDGLMLAS GGKDSVIIVW
     DIVNECGMFR LNGHKASVTH LQFSADGNFL ISSSKDSFVK FWNLSSQSCF YTLTESRSEV
     YTFALLDSDN LLLLGTASLE ILVFQLHWFD REELDVGEDE RSNKFSKLSE GDYEDETQSN
     RIMLCKKRGE LLRHSKGRAL QFSVSPDKRI LICVGSSEMV DIFRLYNAEE RQKRVAKKIK
     KAVKRKEESG SSENVSPTEI AKDVTVLVSH IGKHQFDSKV KWIDFCPSVQ NSGHNLLTYK
     FFSLLTSNTV NSTSLEVDLK LNIVECKTVA SLDQLGHRSD VRCLANAESD FGFASGSSES
     VLVWSRHSLS VVHVCETEEM KNVTALLFLP GDRHILAGTK DGNMFLFELA SNELVQTYKK
     VHSAAIWKLI NSPDKKGCIS CGADKHIRYW DYILEPEKYL ITFNDDLNLS VCRKRAAIRE
     RRELELPDEV LSIASSSDSR FISAALLDNT ARIYFVDSFK LSFTLYGHSL PVTTIDFSPD
     SKLVVTGSAD KSVRIWGADY GDCHKHMHAH DDIITMFRVT CVQFVPNEPL FWSAGKDGLL
     KQWDAVKFYR IQVLELHFAA IWSISQTASG NFLISSSHDK SIRVWELTEE IIVLQEEEEL
     EREKQREERL TSLEDVIPGE EGSENETGLA AKKSMASIKS AEDLIEAVEI ARKEVFKRID
     EPKSAPHPLI TYLKSSSLEH FILDVIDRIP SSHLENSLLM VPFTFVPDIL RAINVCTTKR
     YKLELASKVA LFLIKIHFNY ITNSFDMVQI IDALRSSLRN EIKELRGTVA FNLAGLRLLQ
     KEIEDSTESK MFTDISKFAK KSKKKLRKAV IRTVV
//