ID A0A158RAQ5_THECL Unreviewed; 950 AA.
AC A0A158RAQ5;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Transcription initiation factor TFIID subunit 12 {ECO:0000313|WBParaSite:TCLT_0000047301-mRNA-1};
GN ORFNames=TCLT_LOCUS474 {ECO:0000313|EMBL:VDM95458.1};
OS Thelazia callipaeda (Oriental eyeworm) (Parasitic nematode).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Thelazioidea; Thelaziidae; Thelazia.
OX NCBI_TaxID=103827 {ECO:0000313|Proteomes:UP000046394, ECO:0000313|WBParaSite:TCLT_0000047301-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:TCLT_0000047301-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDM95458.1, ECO:0000313|Proteomes:UP000276776}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TAF12 family.
CC {ECO:0000256|ARBA:ARBA00007530}.
CC -!- SIMILARITY: Belongs to the TTC27 family.
CC {ECO:0000256|ARBA:ARBA00024020}.
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DR EMBL; UYYF01000034; VDM95458.1; -; Genomic_DNA.
DR STRING; 103827.A0A158RAQ5; -.
DR WBParaSite; TCLT_0000047301-mRNA-1; TCLT_0000047301-mRNA-1; TCLT_0000047301.
DR OMA; VRYEPAH; -.
DR Proteomes; UP000046394; Unplaced.
DR Proteomes; UP000276776; Unassembled WGS sequence.
DR GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR CDD; cd07981; TAF12; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR002885; Pentatricopeptide_rpt.
DR InterPro; IPR003228; TFIID_TAF12_dom.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR013105; TPR_2.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR044244; TTC27/Emw1.
DR PANTHER; PTHR16193:SF0; TETRATRICOPEPTIDE REPEAT PROTEIN 27; 1.
DR PANTHER; PTHR16193; UNCHARACTERIZED; 1.
DR Pfam; PF01535; PPR; 1.
DR Pfam; PF03847; TFIID_20kDa; 1.
DR Pfam; PF07719; TPR_2; 1.
DR SMART; SM00028; TPR; 4.
DR SUPFAM; SSF47113; Histone-fold; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 2.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000276776};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT REPEAT 395..428
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 463..496
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 837..908
FT /note="Transcription initiation factor TFIID subunit 12"
FT /evidence="ECO:0000259|Pfam:PF03847"
SQ SEQUENCE 950 AA; 107278 MW; 60B18E070810169F CRC64;
QKSQYDHGIS ENEIENDLSF DCNLPYKFAR SKLYLWLAKA ILVENSGWLE NGFEKSFLTC
RLVLLWQYLL KDPAIQLKKI LNTLVDIEID STTKAIAAEA YIERMYAHLM YGQVREAKNC
LESAMNIIQI KVEMVGAMGR RTKFQTVLPQ LIAVVKENGD LNQDAEENES VLPRSILLSD
DSLLETVSID SCDPSVTNGK FSSLSLACVL ASCALEQKIQ STDDTVIEKC CSYLNEVIAQ
RRNWALQASA LLQRSEFEKT RSRRVQRACM QLELLSELMV GTEDEVDDDI SKKRLLLLLA
SGLKPFWYVQ SAHAELLCSI GCTSEALAIY EKQENWNLVI QCYQSLGQLE KAERLVRDLL
AKDNTRPAYW CLLGDILHDE NAYEKAIEVS NGRSFQAHRS LGMLMLHRNI YDKSFTHLKR
SLEIQPINAN VWFNLGCCAS KLEKWEESAK ANRECVRYEP AHFQAWNNLA VAYERLNDLE
KAKRLLKEAL KLNFDSPKLR ENYMVLCVRT HDISSAITSY HVLLDSNKQY KDEMILISIT
KMLLALKEED EYSTKSLIDE MCGLLDKISS QQTCSSVIWE CYADLKQPNL KSNIADYEVY
GKLLERSFRS CYNKKDWYKN EASCLSVLKS AKKLLQSMEV LSKMKNGEKS TIKLNIRMTI
QPVISSIEKS FGIDAVESSH CDLKKLVAEV KNFTETIMSS NEQAPTTSIT SATLVTALPI
TVQAASNNSA AYANLSVGEL LQKHRIATVP SRNAALPSIT GNRFPIKPFS QHSCAESTLS
QPSAFLQNGT DEDTSPNLEK KPIFSETASV EAFSAQMLHL QPNQVTASSE TSLISSSHLD
DLIRQIDPTS VLDDSVKVML SDFVEDFVDQ AFLLLIAVID RSCKLARHRG SEKLETKDVE
FVLRRYFNCS TFPSCGSEIR SNGLENIRKS ADVLAHKQRM ALIKKTLKKP
//
