ID A0A158RDU5_HYDTA Unreviewed; 2787 AA.
AC A0A158RDU5;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Filamin {ECO:0000313|WBParaSite:TTAC_0000609901-mRNA-1};
GN ORFNames=TTAC_LOCUS6084 {ECO:0000313|EMBL:VDM30231.1};
OS Hydatigena taeniaeformis (Feline tapeworm) (Taenia taeniaeformis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Hydatigera.
OX NCBI_TaxID=6205 {ECO:0000313|Proteomes:UP000046396, ECO:0000313|WBParaSite:TTAC_0000609901-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:TTAC_0000609901-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDM30231.1, ECO:0000313|Proteomes:UP000274429}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the filamin family.
CC {ECO:0000256|ARBA:ARBA00009238}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; UYWX01020293; VDM30231.1; -; Genomic_DNA.
DR STRING; 6205.A0A158RDU5; -.
DR WBParaSite; TTAC_0000609901-mRNA-1; TTAC_0000609901-mRNA-1; TTAC_0000609901.
DR Proteomes; UP000046396; Unplaced.
DR Proteomes; UP000274429; Unassembled WGS sequence.
DR GO; GO:0043232; C:intracellular non-membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR CDD; cd21311; CH_dFLNA-like_rpt1; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 22.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR044801; Filamin.
DR InterPro; IPR017868; Filamin/ABP280_repeat-like.
DR InterPro; IPR001298; Filamin/ABP280_rpt.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR38537:SF18; FILAMIN-A; 1.
DR PANTHER; PTHR38537; JITTERBUG, ISOFORM N; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF00630; Filamin; 22.
DR SMART; SM00033; CH; 2.
DR SMART; SM00557; IG_FLMN; 22.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF81296; E set domains; 22.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS50194; FILAMIN_REPEAT; 22.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Reference proteome {ECO:0000313|Proteomes:UP000274429};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 46..152
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 170..273
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REPEAT 430..514
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 515..619
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 759..855
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 855..946
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 950..1046
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1047..1142
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1143..1240
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1259..1351
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1356..1455
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1456..1548
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1549..1647
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1648..1747
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1748..1842
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1884..1954
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1954..2046
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2058..2132
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2135..2227
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2247..2325
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2328..2428
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2449..2527
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2530..2621
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2652..2742
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2787 AA; 302340 MW; 0D1DBD4A24255DC0 CRC64;
MYAEANPAGG YFENYDDPGD GYVDEEEEGE IPLAERELAE DAEWKLIQKN TFTRWANEHL
KNKSTSVDDI QFDFADGLRL IDLIESLSGQ KFRHVNRKPS FRTQKLENVT MVLRFLEEQE
GLRLVNIDST DIVDCRLKLI LGLIWTLILH YSITLPLWEG EDYNQGSSGP TPKQRLLAWL
NSKLMERPVK NFTTDWNDGT AIGALVDACA PGLCPDWRDW EPKQKLRNAT EAMNAAEQWL
DVPQLIRPEE MINPRVDEKA MMTYLSQFPS AKLKDGAPLR PRANPASVRA YGPASPPEAY
VRGGSSFAWV TPNTLGSNHI RRQPAEHESS YLASGFQYLI EVSVNHAVLA ETARRFCHQR
WPRHKGEGKH HDSVEFRGLA VCACFSRQRF ACLLFLLGPR SPAPRTQFKV FADNDTDIDW
ELPDNHLSTS LEPRGNKVGM SARFTIDASS AGKGSVEVIV LNPKGQREPC DIVPNMDRPN
TYSCAYVPTQ AGEYRVIIKF ATKEIMNSPF KVMVEGAADP SKASASGPGI EPQGNQVGRR
TFFNIFTTVE VEKEGAGEGI ADCVILDPQG RQDVIKPNIT RQSEDNYLVE YTPKVEGLHS
VNVFFAGQQI PNSPFGVMVG PQAVASPRKP SLPQHAAMQE ANTPQQPQMK EVVKGSFIAS
TLVPPPPPPP HLEGYGGGGL NTPLIIKNLP YFFQLILPDL KTLFGRKQPQ EGSTEYLQEG
PIDVAGVKPL TATKTPVLAS EPPISSLKRP SNQIAPPWQP ACDAKQAYAT GRGIQPHGVR
VQDLADFKVH TEDAGEGVVE AAVVGPNGRE EKCQQRKIGP YTYECVYTPQ QAGPHTVNVR
YGGDHIMLSP FKVDVAPYKE TRIRAFGPGL VSGIVNKPAV FVVETNGETG ALGFSIEGPS
EARIDCADNG DGSATVVYWP TVPGEYAVHI LCNDENIPKS PYMVPISADT GKCDPNAVKC
YGPGLSPGVV AGIPTEFTID ARDAGGPAPF GCELRDETGE PVPIRVRDNG DLTATCTYTA
KRPKKHTVIP TYNGVAVPRA PFRVDVAEPC NPGNVRVYGP GVESITRNEP THFTVDCRQA
GPGNVGISVR DEAGRDVPMD TKDMRDGTFK VSYTPTTAGP TYTVQVFFEN TEVPRSPFKV
PVKPNVDMSR VRVDGLPSTI PVGKPTTFDV VTAGAGPPSA PKPRPNVIVK APNGMRVPSQ
LIESPDGYEA TFTPTQAGPH QVAVDVAGAP VRGSPFPCSA VPTQEAPITT AKQPAAFAAQ
QDPSGLVRAY GDGLRRATAN LPAHFTIDSR EAPPAPLSVT IEGPAEAQIN YTDNGDGTCG
VDYLPVEPGP YTVNVLYKDK HVPGSPFPVQ VTPSGRDMVD VSKVRAYGPG LQPTGVFKES
FAKFTVDAKP IDPAGRGVVK AIVVDPMKQR TACIVQNQGD GTYKCSYSPL LDGLHQVEVF
YDGMPVPGSP FKVHVTPGCD PSRVRAYGPG LEGGYTHEPQ HFTIDLDGAG QGGLGLALEG
PADAQINCVD NKDGTCSVEY LPTKAGNYDM FIKLNDMDIP GSPFSIPIRD RVDPNKVRCY
GPGLEPNGAR AGVPATFTVD ASQAGEAPIA VSHTNRNGRK IPANIVPRQG QPGVYDVTYM
PEDEGSCQIE VKLNNCQVPR SPFMQNVLPA CEPHKVRVTG EGVHPSRSDG LPASQPTTFQ
VDTREAGSGD LELTVTDSEQ RPLQLEVADH GDGVYTCQYQ PEEACSHYVD VKFGGREIPE
SPYCVKVHPV GRPDLCRIEG GNDPRVPIFQ PCAITVNPLD AGMGKVMGRV VTPTGQPAEV
HTVALPNGKI NVCYTPQMLG DHMVEIFCGG QVIPGGRFNQ KAVNLDELIQ PVPEERVERF
PLQTMHSTTL TQYHESTKTT GYYPIDFKLP VGSKFGNLEG VVRTPGGRSI RPTLIDNGDG
TVTAQFQPTE DGLHELDITF NGTPIEGSPF RFYVEPVGSG RVTAYGPGLS HGRVGEPAEF
TLVTREAGAG GLSIAVEGPS KAEIVCRDNK NGTCSASYLP LAPGEYTISI KFMDQHIQGS
PFIANIMEDP MRMTQVMVGT TSEVPLRVSE TDIYNLTATV TNPSGIEQPS MVKRLPNGHL
GISFTPREIG DHLVNVFRNG RPIPNSPFKI YVGESELGNA SRVRVYGRGL REGLANQNCQ
FTVDTRDAGF GGLSLSVEGP SKADIECHDN QDGTCLVTYR PTEPGTYIIH IKYADEPVPG
SPFAVNIGGH PSPRIMERIT RQREVAETTH VGSQCEMNLK IPGVNVLEMT AIVTSPSGRT
ERCVITELDP ANYCIRFVPQ EMGVHTVSVR HRNVHIPGSP FQFTVGPITD GGANKVRVIG
QGIQRGYINR NNEFNIYTRE AGAGNLSIAI EGPSKAEIDF EASYYTLKQD RKDGSCCVSF
RVSEPGEYFC SIRFNDEHVP GSPFRLEIED PSGYYATENR QLSVAAVQDR GLQIGVPMAF
TVNYTGARGR LRAYVVTPSG REEPAVVHPV DVDQNAVRFT PQENGPHLVH VLLDERPIPG
SPFRVLVGQD DFSDPGLVTA SGDGLVRGVV GERSRFFVNT ANAGSGALSV TVDGPSKVQL
NCAERMDGYE FSYTPYAPGT YNITITYDGQ PIVHSPFRAY VTGDAVYGYS EDTAQLIVNT
SGRLVTGPQR SMGYSRADAV TCSGTGLTHA YIGSTNTFTV NAQNAGNDVL YVGVSGPIVP
CEEVNIKHLG DNLFSVQYSV RDRGRHYIMV KWGETHIPGS PFIDAGSRAK NGRAGEEEEE
EEELSLRRDL MPSQLCLASL TQASHVQ
//
