ID A0A161I1C7_9MICO Unreviewed; 481 AA.
AC A0A161I1C7;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Mitomycin radical oxidase {ECO:0000313|EMBL:ANC29989.1};
DE EC=1.5.3.- {ECO:0000313|EMBL:ANC29989.1};
GN Name=mcrA {ECO:0000313|EMBL:ANC29989.1};
GN ORFNames=I598_0401 {ECO:0000313|EMBL:ANC29989.1};
OS Isoptericola dokdonensis DS-3.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
OC Promicromonosporaceae; Isoptericola.
OX NCBI_TaxID=1300344 {ECO:0000313|EMBL:ANC29989.1, ECO:0000313|Proteomes:UP000076794};
RN [1] {ECO:0000313|EMBL:ANC29989.1, ECO:0000313|Proteomes:UP000076794}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DS-3 {ECO:0000313|EMBL:ANC29989.1,
RC ECO:0000313|Proteomes:UP000076794};
RA Kwon S.-K., Kim J.F.;
RT "Complete genome sequence of a soil Actinobacterium, Isoptericola
RT dokdonensis DS-3.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the oxygen-dependent FAD-linked oxidoreductase
CC family. {ECO:0000256|ARBA:ARBA00005466}.
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DR EMBL; CP014209; ANC29989.1; -; Genomic_DNA.
DR RefSeq; WP_068200825.1; NZ_CP014209.1.
DR AlphaFoldDB; A0A161I1C7; -.
DR STRING; 1300344.I598_0401; -.
DR KEGG; ido:I598_0401; -.
DR PATRIC; fig|1300344.3.peg.402; -.
DR OrthoDB; 9775082at2; -.
DR Proteomes; UP000076794; Chromosome.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.40.462.20; -; 1.
DR Gene3D; 3.30.43.10; Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2; 1.
DR InterPro; IPR016166; FAD-bd_PCMH.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016167; FAD-bd_PCMH_sub1.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR006094; Oxid_FAD_bind_N.
DR InterPro; IPR006093; Oxy_OxRdtase_FAD_BS.
DR PANTHER; PTHR42973; BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED; 1.
DR PANTHER; PTHR42973:SF39; FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01565; FAD_binding_4; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR PROSITE; PS51387; FAD_PCMH; 1.
DR PROSITE; PS00862; OX2_COVAL_FAD; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:ANC29989.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000076794}.
FT DOMAIN 56..224
FT /note="FAD-binding PCMH-type"
FT /evidence="ECO:0000259|PROSITE:PS51387"
SQ SEQUENCE 481 AA; 49325 MW; 38C88769B57F588F CRC64;
MSRTTGPTTA LDVPTSEHLA AATDAAAALA RTISGTVLRP DDDGYEEALP GYNLALDHRP
AFVVRAATPG DVALTVRAAV AHGLGVGVRS TGHSAAATGP ADVLLDTSGL ARLEVDPLSR
TATVGAGVRW QAVLDAAAPH GLGGLCGSSP QVGVVGYTLG GGLGPSARTF GFAADHVRSI
DVVTPSGDLV TATPTRHTDL FWALRGAGGA YGVVTAMTFD LIPAAVVRAG ALWFDVGDAP
AVVHRWRELV TDLPDAVSTS VVRLNLPPLP DLPAPLRGRA VVAVRYVRHG DLDAPDPLVD
ALRTTAAPVL DTVGDLPYSA LGAVHADPED PMPLLDRGVA LRELPAEAVD AFLAATPADS
PVVLAELRLL GGAVARPPAV PSAVAGRDAA YTLFVGALGW PAGPPDAAEH LQRVVDALAP
WSTGGSLLNF AGPRDAASAR QVRTAFGPAA YDRLVTLRRR LDPHGVLDPT SRWAVVSDRV
G
//
