ID A0A162H434_9GAMM Unreviewed; 618 AA.
AC A0A162H434;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Propionyl-CoA synthetase {ECO:0000313|EMBL:KZX58747.1};
GN Name=prpE {ECO:0000313|EMBL:KZX58747.1};
GN ORFNames=A3709_17265 {ECO:0000313|EMBL:KZX58747.1};
OS Halioglobus sp. HI00S01.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales; Halieaceae;
OC Halioglobus.
OX NCBI_TaxID=1822214 {ECO:0000313|EMBL:KZX58747.1, ECO:0000313|Proteomes:UP000077184};
RN [1] {ECO:0000313|EMBL:KZX58747.1, ECO:0000313|Proteomes:UP000077184}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HI00S01 {ECO:0000313|EMBL:KZX58747.1,
RC ECO:0000313|Proteomes:UP000077184};
RA Sosa O.A.;
RT "Microbial cycling of marine high molecular weight dissolved organic
RT matter.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZX58747.1}.
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DR EMBL; LWEE01000030; KZX58747.1; -; Genomic_DNA.
DR RefSeq; WP_066052144.1; NZ_LWEE01000030.1.
DR AlphaFoldDB; A0A162H434; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000077184; Unassembled WGS sequence.
DR CDD; cd05967; PrpE; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43347; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43347:SF3; ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000077184}.
FT DOMAIN 7..46
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 51..435
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 499..577
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 618 AA; 67465 MW; 0BD70B20B68032FA CRC64;
MDNLDRWREA AQAVHWFKTP QKVLDDSEPP FYRWFPDGQT NACYNALDVH VAEGRGEQTA
LIYDSPVTDT RRRYTYTQLL DEVARFAGVL ADHGVSRGDR VIVYMPMVPE ALIAMLACAR
LGAVHSVVFG GFASNELAVR IDDATPKLIV SASCGVEPNR IVAYKPLLDA AIELAQHKPD
TCVILQRPMQ PAELIAGRDV DWTQEMADAR AVPCTPVAAN DPLYVLYTSG TTGQPKGVVR
DTGGSIVALK WSMKAIYDVE PGDVYWAASD VGWVVGHSYI VYGPLFSGCT TVIYEGKPVG
TPDPGAFWRV IEDYQVKVLF TAPTAFRAIK KEDPAGSYLE QYNVSSLRSL FLAGERCDPS
TLAWAQQQLK VPVIDHWWQT ETGWPICANC LGIEALPIVP GSPARPVPGY DVQVLDGNGE
QVSAGEIGAL VVKSPLPPGT FTTLWQAEER YQRAYFARYP GYYETGDAGY IDANGYVFVM
ARTDDVINVA GHRLSTGAME EVLAEHPDVA ECAVVGVADP MKGQLPLGLL VLNTGAKRAT
ADVVRESLQL VRDKIGPVAA FKLCTVVERL PKTRSGKILR GTMRSIADGE PWKMPATIDD
PVILDEITEA LRTLGYAA
//
