ID A0A162ZPE5_PHYB8 Unreviewed; 866 AA.
AC A0A162ZPE5;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=ArfGap-domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PHYBLDRAFT_173236 {ECO:0000313|EMBL:OAD68231.1};
OS Phycomyces blakesleeanus (strain ATCC 8743b / DSM 1359 / FGSC 10004 / NBRC
OS 33097 / NRRL 1555).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Phycomycetaceae; Phycomyces.
OX NCBI_TaxID=763407 {ECO:0000313|EMBL:OAD68231.1, ECO:0000313|Proteomes:UP000077315};
RN [1] {ECO:0000313|Proteomes:UP000077315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 1555(-) {ECO:0000313|Proteomes:UP000077315};
RG DOE Joint Genome Institute;
RA Corrochano L.M., Kuo A., Marcet-Houben M., Polaino S., Salamov A.,
RA Villalobos J.M., Alvarez M.I., Avalos J., Benito E.P., Benoit I.,
RA Burger G., Camino L.P., Canovas D., Cerda-Olmedo E., Cheng J.-F.,
RA Dominguez A., Elias M., Eslava A.P., Glaser F., Grimwood J., Gutierrez G.,
RA Heitman J., Henrissat B., Iturriaga E.A., Lang B.F., Lavin J.L., Lee S.,
RA Li W., Lindquist E., Lopez-Garcia S., Luque E.M., Marcos A.T., Martin J.,
RA McCluskey K., Medina H.R., Miralles-Duran A., Miyazaki A., Munoz-Torres E.,
RA Oguiza J.A., Ohm R., Olmedo M., Orejas M., Ortiz-Castellanos L.,
RA Pisabarro A.G., Rodriguez-Romero J., Ruiz-Herrera J., Ruiz-Vazquez R.,
RA Sanz C., Schackwitz W., Schmutz J., Shahriari M., Shelest E.,
RA Silva-Franco F., Soanes D., Syed K., Tagua V.G., Talbot N.J., Thon M.,
RA De vries R.P., Wiebenga A., Yadav J.S., Braun E.L., Baker S., Garre V.,
RA Horwitz B., Torres-Martinez S., Idnurm A., Herrera-Estrella A.,
RA Gabaldon T., Grigoriev I.V.;
RT "Expansion of signal transduction pathways in fungi by whole-genome
RT duplication.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KV440995; OAD68231.1; -; Genomic_DNA.
DR RefSeq; XP_018286271.1; XM_018436977.1.
DR AlphaFoldDB; A0A162ZPE5; -.
DR STRING; 763407.A0A162ZPE5; -.
DR GeneID; 28997883; -.
DR VEuPathDB; FungiDB:PHYBL_173236; -.
DR InParanoid; A0A162ZPE5; -.
DR OrthoDB; 1449795at2759; -.
DR Proteomes; UP000077315; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd08204; ArfGap; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR045258; ACAP1/2/3-like.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR23180:SF160; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN EFFECTOR PROTEIN 1; 1.
DR PANTHER; PTHR23180; CENTAURIN/ARF; 1.
DR Pfam; PF01412; ArfGap; 1.
DR Pfam; PF16746; BAR_3; 1.
DR Pfam; PF00169; PH; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50115; ARFGAP; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000077315};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00288}.
FT DOMAIN 349..455
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 546..683
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 296..327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 475..494
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 718..741
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..31
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 866 AA; 98081 MW; F2B333E03F8A96E2 CRC64;
MADLETRPLQ TIPGPAFNED SPQPISTTRT CADDQDLEDG PLFRATIKQL ENKTSALKAS
TKRILKTAVA SVEAQQALMD ADTNFLDALR DIPSATPPLT EYMDRTWAIL YEQRLRLQQS
MRDIILDPLQ KRYDYEIKTA EYKRRRFEEA SKDYYSYLAK YLSIKPETLS KDKKRTEREQ
KHIARQSAFD LIRFDYYNFL VDLHGGKKEQ EMLFNLVRNQ QEESSFYQFI SSGVIPHKEA
LDNVATLMEE AAREQDTFYK ERSEKRRTML TRHNQHVKDM LKTEYIKEQA QLKRTSLRTS
ANVSDVEENP ISTDPGLPEP SQSAGSAENR FKGIHDLENQ DRNMLWACGR RKEGVLFSTS
KPSKGTAFEK GSNVTWHKYW CVLSGGQLHE YSNWKRHVES HIDPIPLRYA TVRQACNADR
QFCFEIITPY FRRMYQAISQ EEMMSWMATI RNAIESLLNG TGSSVNLIKD HLIKEEETNN
DQSPKKGHSR SLSKAIRRGL AERSRWSGFS FTSNSNGSAG HGHIAKNSGA VGQYEFSPSP
DATVNTKLLT TLREDRSNVL CADCGERNPE WCSLNLGILL CIECSGIHRS LGTHISKVRS
LTLDSASYTP DIVELLRSIG NARSNAVWDP KRCLTTNDDD CLTTDEVDEL RRPVPGDTRD
FKLKYIQQKY VEKAFVYHTH KDLNTLLFDA IDNDDIPAAL YAVALGIDLN RSWPFTSARS
SSSDEDGSQN SRNSQDSIPL PTIVLSSGNN LCATNTTGRD KIDDPTVRYP LHYALLYGRR
TLPSVMTDRN RLFPMAEFLL QNGADAGIID PETGNTLASI VGLGSIVEDD AIAYLNLKNA
ARGQPQIFRA SMPIIPSHSF IDATYK
//
