ID A0A164HMU9_9NOCA Unreviewed; 224 AA.
AC A0A164HMU9;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Crp/Fnr family transcriptional regulator {ECO:0000313|EMBL:KZM68648.1};
DE SubName: Full=Cyclic nucleotide-binding domain-containing protein {ECO:0000313|EMBL:QIS17284.1};
GN ORFNames=AWN90_12510 {ECO:0000313|EMBL:KZM68648.1}, CRH09_02560
GN {ECO:0000313|EMBL:ATL65274.1}, F6W96_02105
GN {ECO:0000313|EMBL:QIS17284.1};
OS Nocardia terpenica.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=455432 {ECO:0000313|EMBL:KZM68648.1, ECO:0000313|Proteomes:UP000076512};
RN [1] {ECO:0000313|EMBL:KZM68648.1, ECO:0000313|Proteomes:UP000076512}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IFM 0406 {ECO:0000313|EMBL:KZM68648.1,
RC ECO:0000313|Proteomes:UP000076512};
RA Evans L.H., Alamgir A., Owens N., Weber N.D., Virtaneva K., Barbian K.,
RA Babar A., Rosenke K.;
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ATL65274.1, ECO:0000313|Proteomes:UP000221961}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NC_YFY_NT001 {ECO:0000313|EMBL:ATL65274.1,
RC ECO:0000313|Proteomes:UP000221961};
RA Zeng L.;
RT "Comparative genomics between pathogenic Norcardia.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:QIS17284.1, ECO:0000313|Proteomes:UP000500953}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AUSMDU00012715 {ECO:0000313|EMBL:QIS17284.1,
RC ECO:0000313|Proteomes:UP000500953};
RX PubMed=31697466;
RA Herisse M., Ishida K., Porter J.L., Howden B., Hertweck C., Stinear T.P.,
RA Pidot S.J.;
RT "Identification and Mobilization of a Cryptic Antibiotic Biosynthesis Gene
RT Locus from a Human-Pathogenic Nocardia Isolate.";
RL ACS Chem. Biol. 0:0-0(2019).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP023778; ATL65274.1; -; Genomic_DNA.
DR EMBL; LWGR01000021; KZM68648.1; -; Genomic_DNA.
DR EMBL; CP046173; QIS17284.1; -; Genomic_DNA.
DR RefSeq; WP_011206875.1; NZ_KV411303.1.
DR AlphaFoldDB; A0A164HMU9; -.
DR STRING; 455432.AWN90_12510; -.
DR GeneID; 80364963; -.
DR KEGG; ntp:CRH09_02560; -.
DR OrthoDB; 892842at2; -.
DR Proteomes; UP000076512; Unassembled WGS sequence.
DR Proteomes; UP000221961; Chromosome.
DR Proteomes; UP000500953; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR012318; HTH_CRP.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR24567; CRP FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR PANTHER; PTHR24567:SF80; CRP-LIKE CAMP-ACTIVATED GLOBAL TRANSCRIPTIONAL REGULATOR; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF13545; HTH_Crp_2; 1.
DR SMART; SM00100; cNMP; 1.
DR SMART; SM00419; HTH_CRP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
DR PROSITE; PS51063; HTH_CRP_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000076512}.
FT DOMAIN 10..130
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 144..217
FT /note="HTH crp-type"
FT /evidence="ECO:0000259|PROSITE:PS51063"
SQ SEQUENCE 224 AA; 24762 MW; 402C91B30B741564 CRC64;
MDEALARAGI FQGVEPTAVA ALAKQLQPVD FPRGHVIFNE GEPGDRLYII TSGKVKIGRR
SPDGRENLLT IMGPSDMFGE LSIFDPGPRT STATTVTEVR AVTMDRDALK SWIDQRPEIA
EQLLRVLARR LRRTNNNLAD LIFTDVPGRV AKALLQLAQR FGTQEAGALR VTHDLTQEEI
AQLVGASRET VNKALADFAH RGWLRLEGKS VLISDSERLA RRAR
//
