ID A0A164VCK1_9CRUS Unreviewed; 556 AA.
AC A0A164VCK1;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Endothelial lipase {ECO:0000313|EMBL:KZS12190.1};
GN ORFNames=APZ42_022984 {ECO:0000313|EMBL:KZS12190.1};
OS Daphnia magna.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=35525 {ECO:0000313|EMBL:KZS12190.1, ECO:0000313|Proteomes:UP000076858};
RN [1] {ECO:0000313|EMBL:KZS12190.1, ECO:0000313|Proteomes:UP000076858}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Xinb3 {ECO:0000313|EMBL:KZS12190.1,
RC ECO:0000313|Proteomes:UP000076858};
RC TISSUE=Complete organism {ECO:0000313|EMBL:KZS12190.1};
RA Gilbert D.G., Choi J.-H., Mockaitis K., Colbourne J., Pfrender M.;
RT "EvidentialGene: Evidence-directed Construction of Genes on Genomes.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC {ECO:0000256|ARBA:ARBA00010701, ECO:0000256|RuleBase:RU004262}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZS12190.1}.
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DR EMBL; LRGB01001363; KZS12190.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A164VCK1; -.
DR STRING; 35525.A0A164VCK1; -.
DR ESTHER; 9crus-a0a0p5czr0; Pancreatic_lipase.
DR Proteomes; UP000076858; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0004806; F:triglyceride lipase activity; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd00707; Pancreat_lipase_like; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 2.60.60.20; PLAT/LH2 domain; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR013818; Lipase.
DR InterPro; IPR033906; Lipase_N.
DR InterPro; IPR002331; Lipase_panc.
DR InterPro; IPR036392; PLAT/LH2_dom_sf.
DR InterPro; IPR000734; TAG_lipase.
DR PANTHER; PTHR11610:SF184; LD47264P; 1.
DR PANTHER; PTHR11610; LIPASE; 1.
DR Pfam; PF00151; Lipase; 1.
DR PRINTS; PR00823; PANCLIPASE.
DR PRINTS; PR00821; TAGLIPASE.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF49723; Lipase/lipooxygenase domain (PLAT/LH2 domain); 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000076858};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 38..358
FT /note="Lipase"
FT /evidence="ECO:0000259|Pfam:PF00151"
FT REGION 537..556
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 556 AA; 62421 MW; 83A42EBD06499323 CRC64;
MENIIFNVWL KKKKNTSLPH HERTTRGIRT AVSNKPTERC YGTFGCYSVN RPWTSSNRPI
NNFPEAPEII QPAFCLYTRH NRSRCQNLVT GDVNSIQRSG LDSSRRLLFI VHGYLEHGNK
KWIKRMVEEA LIYDNINVVV VDWVSGSGPP YTQAVANIRL IGVMLAHLLL FLHAQFQVPT
ENCHITGHSL GAHLAGYTGQ YLRDRGHMLG RITGMDPADP YFENTEPLIR LDPTDALFVD
VIHTDAGPIL SGGLGMMQPV GHIDFYPNGG VRQPGCGTSV LDSIEKERGS VLYGLSRFIG
CNHLRSVEFF TESFNSACPF LAVQCPSFED FLEGRCHCGT NACHRMGYSA DHQSVASSTG
LNWPGQQQTD DSIQMYLLTR DDQPFCLYHY RVTIVISDTF ESIQHGGDRG WLSIQLHGHN
RSSPPTRLTP ENVRFEPRRA YSYVLGSTWL GDIKSVTLVW TYSSSVFNPL TWRILTVPAL
HVNRIIVHNL ESNSSAVICG EDTPISSKES RQMFPDSKCR HQSWLPAAGS FHFPTDETGA
NGLRKSGKRS RRLQLG
//
