ID A0A164WP98_9CRUS Unreviewed; 624 AA.
AC A0A164WP98;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 08-NOV-2023, entry version 24.
DE SubName: Full=Rac GTPase-activating protein {ECO:0000313|EMBL:KZS13451.1};
GN ORFNames=APZ42_021397 {ECO:0000313|EMBL:KZS13451.1};
OS Daphnia magna.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=35525 {ECO:0000313|EMBL:KZS13451.1, ECO:0000313|Proteomes:UP000076858};
RN [1] {ECO:0000313|EMBL:KZS13451.1, ECO:0000313|Proteomes:UP000076858}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Xinb3 {ECO:0000313|EMBL:KZS13451.1,
RC ECO:0000313|Proteomes:UP000076858};
RC TISSUE=Complete organism {ECO:0000313|EMBL:KZS13451.1};
RA Gilbert D.G., Choi J.-H., Mockaitis K., Colbourne J., Pfrender M.;
RT "EvidentialGene: Evidence-directed Construction of Genes on Genomes.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZS13451.1}.
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DR EMBL; LRGB01001151; KZS13451.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A164WP98; -.
DR STRING; 35525.A0A164WP98; -.
DR Proteomes; UP000076858; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd20821; C1_MgcRacGAP; 1.
DR CDD; cd04382; RhoGAP_MgcRacGAP; 1.
DR Gene3D; 3.30.60.20; -; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR046349; C1-like_sf.
DR InterPro; IPR002219; PE/DAG-bd.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR46199:SF3; FI24033P1-RELATED; 1.
DR PANTHER; PTHR46199; RAC GTPASE-ACTIVATING PROTEIN 1; 1.
DR Pfam; PF00130; C1_1; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00109; C1; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
DR PROSITE; PS00479; ZF_DAG_PE_1; 1.
DR PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000076858};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 328..377
FT /note="Phorbol-ester/DAG-type"
FT /evidence="ECO:0000259|PROSITE:PS50081"
FT DOMAIN 398..580
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 173..193
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 236..270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 37..106
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 240..256
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 624 AA; 70193 MW; 5B587C5C130C2E9D CRC64;
MSAKQVSVLA QYDDLCRGFN YFINSSEKEF LKFAVNQEAC RQKWLEAEAE LRRLQNQLNE
VNKMNGKLEL QYHHATVLLK NEIKVRKQVS DEKKSLEKQL HIVREIVSAE KDIRDETREK
LAMLSNTGRY SRGNFESPGD RLNTINEMNS TGSLLASFDL TTERTEEELE LSVMRSSRAP
RSKRPSEGMC YNLDNSKRYK TNRENIMEVS GNERMVATTT VTVNKGGPIT ATSIIENCPD
VGKENDDGHV TPRNQRKRSS SEPGIIPNAP PQCKYLIESS WELPDGKTPV AIRRPSANPS
ASAQSTHTLG GTAYLRTMAS GGRINQRQHT FSQKTIIKPE NCLPCGNRIK FGKPALKCIE
CRGTCHVDCK SRMPMPCVPT VQTPSNKGFV GTVADYAPNI SPMIPGIVIH CVNEIERRGL
NEVGIYRVNG SEKEIKDMKE RLLRGKGQPT LSQIDIHVVT GTLKLFFRSL KEPLITYTLW
DSFVRIADLN DEMDIQTTVY SLVPDLPQPN RDTLAYLILH LQRVAEAEIC KMPITNLAKI
FGPTIIGYSC PDPLPEMALK QLKKQHLTME RLLLIPSDYW TRYVDADTET FTSTPVSSRH
PGVATIAKSV KRGPTFFSSP NMIN
//
