ID A0A165S4Q6_9APHY Unreviewed; 1320 AA.
AC A0A165S4Q6;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 22-FEB-2023, entry version 20.
DE RecName: Full=DH domain-containing protein {ECO:0000259|PROSITE:PS50010};
GN ORFNames=DAEQUDRAFT_110220 {ECO:0000313|EMBL:KZT71528.1};
OS Daedalea quercina L-15889.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Daedalea.
OX NCBI_TaxID=1314783 {ECO:0000313|EMBL:KZT71528.1, ECO:0000313|Proteomes:UP000076727};
RN [1] {ECO:0000313|EMBL:KZT71528.1, ECO:0000313|Proteomes:UP000076727}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L-15889 {ECO:0000313|EMBL:KZT71528.1,
RC ECO:0000313|Proteomes:UP000076727};
RX PubMed=26659563; DOI=10.1093/molbev/msv337;
RA Nagy L.G., Riley R., Tritt A., Adam C., Daum C., Floudas D., Sun H.,
RA Yadav J.S., Pangilinan J., Larsson K.H., Matsuura K., Barry K., Labutti K.,
RA Kuo R., Ohm R.A., Bhattacharya S.S., Shirouzu T., Yoshinaga Y.,
RA Martin F.M., Grigoriev I.V., Hibbett D.S.;
RT "Comparative Genomics of Early-Diverging Mushroom-Forming Fungi Provides
RT Insights into the Origins of Lignocellulose Decay Capabilities.";
RL Mol. Biol. Evol. 33:959-970(2016).
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DR EMBL; KV429045; KZT71528.1; -; Genomic_DNA.
DR STRING; 1314783.A0A165S4Q6; -.
DR OrthoDB; 24699at2759; -.
DR Proteomes; UP000076727; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR PANTHER; PTHR12673:SF270; DH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12673; FACIOGENITAL DYSPLASIA PROTEIN; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000076727}.
FT DOMAIN 102..294
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 639..662
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 693..758
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 818..904
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 930..1041
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1085..1113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1140..1171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 693..709
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 729..744
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 846..876
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 879..897
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 989..1028
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1087..1101
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1151..1167
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1320 AA; 146164 MW; FD9638756C3FD8A2 CRC64;
MALNLSPRKV VPLASGDEPR PRFKTRSTLP SVTKRVFLCG VVVEGAGDGP IPDDVQDMLV
TLGELIETES GSSSMRSPTS TSTSAHTFTT GSRMFAAANA PALEENIKEL VATERSYVER
LKSLKENYAD PLRSFARGKE TSILPAYEAN TLFGNIDSIL PVNEAFLKDL ERVLTPRGPG
VGDIALKHFK VNRGFEHYKM YYSKREEAQR IFETQVKKNS SFVAYMDRIK YSATETRNLI
GLRELLMEPV QRIPRYTLLF RLMIKHMGPD DPQRAKLIEA DEIASHIALA ETDENTKRAE
KMFCLQNSIE DFPPGLLSNS RRLIDCIDVE DVADAGLGGY ALASDAPSTT TLHCTLFLFD
DKLMIVRRPS DKGGKALTGL DDIDKPAAKA RPLSIRKLKK GQMSCKGVVD IMDVVATDVG
GSEMHMYIEK PPHDQGDRWS GRPFRPFFAV HPPSSQRDTK LGEERKQQFL ENLWDAQAKY
RTRDGHSALI RAEEREVESY AGRTTIARTY FNVYTRPWYL GEDSKPKVIV HIDPMGTGDP
IPFGGRNPPY VVIKVQPMPG ALSRYEVTSN DPVDETENDI VHNDVVPARI VQTIHQYGLF
KFSTGQNSRP TTPTATRSRA AIFGLDVISR NLFNSRSGAV TNDLFGGSTN SSRRTRTVAS
RSSVYTGTMS TVGHGSSLSR FSQATSTLTA ATSLEDEQSF SGSKNSRRSQ SLSRPKKLVK
KTSTPKLDDS VSEPESSPNR SNHRPISRSR SEPGDVRDDE DDAAILHFPA FTDPEDMDLA
SKLELAQRNR QTQASEHWAH LDLDQPIDEN IYDEEPAVSR PLSRVSRTAR QLPGIPAAAR
SRSPSLRREL SVETRTITPD LHRARSLSRH SSDRRPMGPR SPSPMPPRTP SPMPSRALSP
PLSWVSPQTY TLDSAPSLEA DLAHEATLVN APQSPGDSPG PLATPKRPRI PRSKRQPFDP
TENLETTPKA EHIGTPQTAV IIEPLSIKKK SSVASSTRNS PSRSRPSSAQ TARASPRNKR
STGHKVSSGS PGAPPAPLSP ALASSEEIAR LVRLVETTKE DVESSRRAVK RIRLETVKLR
SMTPVAESPS PIKQTDPFMR SASPFGSPVK TRIPVVSEPK PEFKDREARL KEMHMMIGRR
KGREASQPAW KQEGSPLQPQ TPGGSGTPTR VHDVADSVDN LLEHADRALE KVAVGQHAIQ
SDVEKVVALL NQKTSELITA QTQLKSTRVQ LETVKALVDH SRDEKDYLFD AFNEQLDQMF
EDATLAAEDA WVAMTRDLKA TKKAEKLAVQ DNTRLKRRLE AMEMQQEEWG ALLRAHGLIP
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