ID   A0A165UBZ2_9APHY        Unreviewed;      1198 AA.
AC   A0A165UBZ2;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=RNA-dependent RNA polymerase {ECO:0000256|RuleBase:RU363098};
DE            EC=2.7.7.48 {ECO:0000256|RuleBase:RU363098};
GN   ORFNames=DAEQUDRAFT_734301 {ECO:0000313|EMBL:KZT74695.1};
OS   Daedalea quercina L-15889.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Polyporales; Daedalea.
OX   NCBI_TaxID=1314783 {ECO:0000313|EMBL:KZT74695.1, ECO:0000313|Proteomes:UP000076727};
RN   [1] {ECO:0000313|EMBL:KZT74695.1, ECO:0000313|Proteomes:UP000076727}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L-15889 {ECO:0000313|EMBL:KZT74695.1,
RC   ECO:0000313|Proteomes:UP000076727};
RX   PubMed=26659563; DOI=10.1093/molbev/msv337;
RA   Nagy L.G., Riley R., Tritt A., Adam C., Daum C., Floudas D., Sun H.,
RA   Yadav J.S., Pangilinan J., Larsson K.H., Matsuura K., Barry K., Labutti K.,
RA   Kuo R., Ohm R.A., Bhattacharya S.S., Shirouzu T., Yoshinaga Y.,
RA   Martin F.M., Grigoriev I.V., Hibbett D.S.;
RT   "Comparative Genomics of Early-Diverging Mushroom-Forming Fungi Provides
RT   Insights into the Origins of Lignocellulose Decay Capabilities.";
RL   Mol. Biol. Evol. 33:959-970(2016).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.48; Evidence={ECO:0000256|ARBA:ARBA00024517,
CC         ECO:0000256|RuleBase:RU363098};
CC   -!- SIMILARITY: Belongs to the RdRP family. {ECO:0000256|ARBA:ARBA00005762,
CC       ECO:0000256|RuleBase:RU363098}.
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DR   EMBL; KV429032; KZT74695.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A165UBZ2; -.
DR   STRING; 1314783.A0A165UBZ2; -.
DR   OrthoDB; 5477883at2759; -.
DR   Proteomes; UP000076727; Unassembled WGS sequence.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProt.
DR   InterPro; IPR007855; RNA-dep_RNA_pol_euk-typ.
DR   PANTHER; PTHR23079; RNA-DEPENDENT RNA POLYMERASE; 1.
DR   PANTHER; PTHR23079:SF17; RNA-DEPENDENT RNA POLYMERASE; 1.
DR   Pfam; PF05183; RdRP; 1.
PE   3: Inferred from homology;
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU363098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000076727};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU363098};
KW   RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW   ECO:0000256|RuleBase:RU363098};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363098}.
FT   REGION          93..115
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        101..115
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1198 AA;  134716 MW;  C6D8EAADCA4B8B44 CRC64;
     MEICMYNIAA NVDEVLLKNR LADILHGPRY THLSTHPIDF AVRIFSQSPP KRNNGFLTVP
     TISIAEQFLQ EFGGKPAKYR LILGKPIFFK QSKRSPRRRQ IKELQRPPAT GRRFAEHREH
     ATDPAMASVG VSELQFGYFC RDDEYSIEWK KVPGLAAQLV LDDARNAFEI IWHERTHTQY
     VIFRAASIYW IGAGLDSTGW AVVFFALNHA PSFQTSGPQY PAKILKREKR YTARLCAFDA
     DHMPLAPYTS NAIRIICKTA GDLDVFRSLG GLAQVQIEET LYPATERALF AHNIRRTYQK
     WITRTPWSIA FQVEALVQAS LVELREVLQE LRPMIAKMVE RHGPDPTSAF LHDFRMRVKE
     ITMAGEGISL RDVWIAALDE FQQRPPSLAV PVDDNEDLFQ CFHVIVTPTT MFLEGPFPEQ
     SNRVIRRYKA NQDCFIRVSF LDETRLAYRS DRNVNISGMI KMRVRQFLVE GLPVAGRAFE
     FLAYSQSGLK EHSVWFVKPF RSGGRAVSAA SIIQGLGSFR ALPYDPLLMY CPARYAARLS
     QAFTATDSAL SVQTEDMIAI PDILTHDRQY CFTDGVGTLS PDLARAIWGQ LRAKGRRVGH
     ASTYPRLFQI RLGGSKGMLS VDHCLTGLAV GLRPSMTKFD APHSLSIEIA RAFDRPSKYY
     LNRPLIMLLE GLGTPYGVFQ RLQDDAVRDA QRATASLDQA AHLLEAHGLG ASYKLSSIMR
     NLHRLGVGAF TGDVFWQRMM DFAVNHVLRE LKHHARIPVP LGWTLVGVAD IYEYLQEDEI
     FACVDASDEA GLVYLEGPIM ISRSPSIHPG DIQIVHAIGK PPEGSPYERE PLRNGVVFAT
     KGRRPVSTCL GGGDLDGDVY NLTPMSELHP PKISEPAAYE PAVRMAIKKE STMEDVADFV
     THYITNDTLG VVATHWLITA DQREDGIFDE DCLKLSKLHS IAVDYPKTGR SVSLYNIPKL
     KSKVKPDWYA PETQANNRKR YYESQRAIGK LSRAIKLPAL KAFASSRPRH MEDGQGHLHR
     DIVNQFHSHS AGECDVFARL TVRHSVEEFI YVSQANIPDD MVVFMGQLLA SYASQLRSIC
     AMNSISEYSG SAMLTEEEAM IGTIAEKTSQ PRRRTDAMGR LRDHTERLVK AVRAEISGVD
     GTPPRRSLKR AWVAYNVGLL KGVYFGAGSF AWIALGEIFD AIRDIEEEER SLLRRAHA
//