ID A0A166R898_9EURY Unreviewed; 889 AA.
AC A0A166R898;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Beta-galactosidase {ECO:0008006|Google:ProtNLM};
GN ORFNames=A4G99_19180 {ECO:0000313|EMBL:KZN22589.1};
OS Haladaptatus sp. R4.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haladaptataceae; Haladaptatus.
OX NCBI_TaxID=1679489 {ECO:0000313|EMBL:KZN22589.1, ECO:0000313|Proteomes:UP000076599};
RN [1] {ECO:0000313|EMBL:KZN22589.1, ECO:0000313|Proteomes:UP000076599}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R4 {ECO:0000313|EMBL:KZN22589.1,
RC ECO:0000313|Proteomes:UP000076599};
RA Mukhopadhyay S.K.;
RT "Genome sequence of halophilic archaea.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZN22589.1}.
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DR EMBL; LWHG01000033; KZN22589.1; -; Genomic_DNA.
DR RefSeq; WP_066148623.1; NZ_LWHG01000033.1.
DR AlphaFoldDB; A0A166R898; -.
DR STRING; 1679489.A4G99_19180; -.
DR OrthoDB; 256347at2157; -.
DR Proteomes; UP000076599; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR42732:SF3; BETA-MANNOSIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 14..166
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 168..264
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 271..490
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
SQ SEQUENCE 889 AA; 100961 MW; 7B013647B53FACB6 CRC64;
MSLLNTQTRE RTLLDGEWVF LIDREDNGTQ QGYQEIDNNW PNEETQKVTV PHSWQGSDAY
QDYTGTAWYR TTVDYPNNDG RIFLQFNAVD YEATIYVNGI DVGSHRGGYL PFELEVTDAI
SSGENTIVVK VNDQEDITEI PHGKQGTPWY TRVSGIWQSV ALERRPETFI SDMKITPNLE
NDSATFDIEI NENSNAEVKI QVTQGNEAVA ESTCDLSSGS GSYTVNLPDP EYWTPENPVI
YDVSVSLYIA GLSVDEYCDY FGMRSISHDG DQLYLNEEPL YIRGALDQAY YPDTHYRPLE
EDIFESEIRM AKEMGFNLLR KHIKPAHPDF IEAADRQGIL VWEEPANPTV YTERSKREVR
EQLEELVDRD YNSPSVIIWS IYNEEWGIGL DQIDHSDHSS RLWNSEEKQT YLTDLFYDIK
DLDPTRLVCD NSGWAHVATD LNDYHEYYVS PDRAVEWGES LDEIAQNPGD NFATENISAD
EAPMLISEFG TWGLCDIERL RDHYEGDPPW FSHEFLDDPL KRGEGLDKRY ESTLLPDVFN
GYDELASVWQ QRQWDSIKDV IEQMRTHDRI VGYCITEFSD IEWEFNGMLD YFREPKSFVD
ELPKVNGEVI TSIDPDSHVV EPGETITVDI DIVNDSNEHL SGTLRWNAVG DNGSQSVDID
SFGTTKVAEE LQIEVPEDVS PNRQKISVTV ELEDKIATNE EPLIIIPHEE PGDSIVYAEG
DLANRLVAGG ITVVENVVDA DLALIQSLNS EVESFVKEGG TAVVLPKEDG RMVDNSIFKY
RSLPEGESWN LVAALPYQDS ELLADISPDH RIGWEFEGLF PHDLVEDINP ETDTIQVGHI
EGWLANWGSP LLVREFGDGR ICSCTFRIAS NYGDHPTATL LTNRLLDSL
//
