ID A0A166SE29_9ACTN Unreviewed; 627 AA.
AC A0A166SE29;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Transketolase {ECO:0000313|EMBL:OAA28040.1};
DE EC=2.2.1.1 {ECO:0000313|EMBL:OAA28040.1};
GN ORFNames=UG55_100612 {ECO:0000313|EMBL:OAA28040.1};
OS Frankia sp. EI5c.
OC Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae; Frankia.
OX NCBI_TaxID=683316 {ECO:0000313|EMBL:OAA28040.1, ECO:0000313|Proteomes:UP000077018};
RN [1] {ECO:0000313|EMBL:OAA28040.1, ECO:0000313|Proteomes:UP000077018}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EI5c {ECO:0000313|EMBL:OAA28040.1,
RC ECO:0000313|Proteomes:UP000077018};
RX PubMed=27389275;
RA D'Angelo T., Oshone R., Abebe-Akele F., Simpson S., Morris K., Thomas W.K.,
RA Tisa L.S.;
RT "Permanent Draft Genome Sequence for Frankia sp. Strain EI5c, a Single-
RT Spore Isolate of a Nitrogen-Fixing Actinobacterium, Isolated from the Root
RT Nodules of Elaeagnus angustifolia.";
RL Genome Announc. 4:e00660-16(2016).
RN [2] {ECO:0000313|EMBL:OAA28040.1, ECO:0000313|Proteomes:UP000077018}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EI5c {ECO:0000313|EMBL:OAA28040.1,
RC ECO:0000313|Proteomes:UP000077018};
RA Wen L., He K., Yang H.;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the transketolase family.
CC {ECO:0000256|ARBA:ARBA00007131}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAA28040.1}.
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DR EMBL; LRTK01000006; OAA28040.1; -; Genomic_DNA.
DR STRING; 683316.UG55_100612; -.
DR PATRIC; fig|683316.3.peg.778; -.
DR OrthoDB; 8732661at2; -.
DR Proteomes; UP000077018; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProt.
DR GO; GO:0004802; F:transketolase activity; IEA:UniProtKB-EC.
DR CDD; cd07033; TPP_PYR_DXS_TK_like; 1.
DR CDD; cd02012; TPP_TK; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR020826; Transketolase_BS.
DR InterPro; IPR033248; Transketolase_C.
DR InterPro; IPR005474; Transketolase_N.
DR PANTHER; PTHR43195:SF1; FI06132P-RELATED; 1.
DR PANTHER; PTHR43195; TRANSKETOLASE; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR Pfam; PF00456; Transketolase_N; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
DR PROSITE; PS00802; TRANSKETOLASE_2; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Reference proteome {ECO:0000313|Proteomes:UP000077018};
KW Thiamine pyrophosphate {ECO:0000256|ARBA:ARBA00023052};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:OAA28040.1}.
FT DOMAIN 318..480
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 627 AA; 65955 MW; AF161B4F581F11C3 CRC64;
MATPVSDVVG VADLXTVREL AQQLRVDSVR SSTSAGSGHP TSSMSAADVM AVLLTRHLRY
DWDKPDDPAN DHLIFSKGHA SPLIYSMFKA VGVISDDELM TGYRRFGHRL QGHPTPILPW
VDVATGSLGQ GLPDAVGVAL AGKFLDKVPY RVWVVCGDSE MAEGSMWEAL DKASFYGLSN
LIAIVDVNRL GQRGPTELGW DLAAYARRVE AFGARAVTID GHDLGAIDAA LADAEDASRP
TVILARTRKG DGFSEVADAE GWHGKPFSED MAARAIVELG GERNLRVRGP VPPADFPRPA
PPVHPAVTLP TYELGAKVAT RRAYGQALAA VGVRTDVVAL DAEVSNSTYS EDFTKAHPDR
FFEIFIAEQQ LVAAAVGLAV RGYIPFASTF AAFLSRAYDF IRMAAISQAD IRLSGSHAGV
EIGPDGPSQM ALEDLAMMRA VGGSTVLYPS DATSAAKLVE AMTEISGVSY LRTTRGAYPV
LYGPDETFAP GGSKVLRSSE ADTVTLVGAG VTLHHCLAAA DVLASEGVSA RVIDLYSVKP
VDAATLAEAA RATGGRLVVV EDHYPEGGLG AAVLEGLAGV LRDGSVSLRL AHLAVTELPG
SGTPDELLDF AGISAPHIAE AARGLLR
//
