ID A0A168GAW6_CORDF Unreviewed; 427 AA.
AC A0A168GAW6;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=INSIG domain protein {ECO:0000313|EMBL:OAA76256.1};
GN ORFNames=LEL_05940 {ECO:0000313|EMBL:OAA76256.1};
OS Akanthomyces lecanii RCEF 1005.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Akanthomyces;
OC Cordyceps confragosa.
OX NCBI_TaxID=1081108 {ECO:0000313|EMBL:OAA76256.1, ECO:0000313|Proteomes:UP000076881};
RN [1] {ECO:0000313|EMBL:OAA76256.1, ECO:0000313|Proteomes:UP000076881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCEF 1005 {ECO:0000313|EMBL:OAA76256.1,
RC ECO:0000313|Proteomes:UP000076881};
RX PubMed=27071652; DOI=10.1093/gbe/evw082;
RA Shang Y., Xiao G., Zheng P., Cen K., Zhan S., Wang C.;
RT "Divergent and convergent evolution of fungal pathogenicity.";
RL Genome Biol. Evol. 8:1374-1387(2016).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the INSIG family.
CC {ECO:0000256|ARBA:ARBA00007475}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAA76256.1}.
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DR EMBL; AZHF01000004; OAA76256.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A168GAW6; -.
DR STRING; 1081108.A0A168GAW6; -.
DR OrthoDB; 2730354at2759; -.
DR Proteomes; UP000076881; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR025929; INSIG_fam.
DR PANTHER; PTHR15301; INSULIN-INDUCED GENE 1; 1.
DR PANTHER; PTHR15301:SF3; PROTEIN NSG1-RELATED; 1.
DR Pfam; PF07281; INSIG; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000076881};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 301..318
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 325..342
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 391..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 106..164
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..32
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 427 AA; 44694 MW; D5E59F11FF835D60 CRC64;
MSDDGPLLIR PVPRRPFTLS RQSATPTTDD EPSTPDAAAA ASSASGPATA AIGTTSSPGL
MHNHLTAALA AWSRSGDASE QPSPAISRPA SIMNLTSSTL YGIYSPTAGG GRDRDDVEDS
PWGMGAQTPI RRPDIDEPTF ALMRERSHLD RRRRRSSYKG ADLPRVPAPH LSSAQVAART
AVLFILGLGY GALVTRLHDQ DQGVATAEGL VEPGFNSTYL GAWGVAGVVL GSLLPWFDGV
WEERFGASDE EEEEDCAVAD GENAPSKAVD TGLDSALVMR AIGAFVGIVF AIRKLAWDST
FQISATLALA NPLLWWLIDR SKPGLLLSAG VGLVGSLLLL GISPDMMPTP SLQILRNAAA
AAAAAAANGN TTATAAPGAL VAHNQIIETG VWMLSVLFCS CLCFGNIGRR LFLGRSAAGR
GRWGGVR
//
