ID A0A168I6Z0_CORDF Unreviewed; 1430 AA.
AC A0A168I6Z0;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 22-FEB-2023, entry version 26.
DE SubName: Full=HR1 repeat, rho-binding protein {ECO:0000313|EMBL:OAA78847.1};
GN ORFNames=LEL_02333 {ECO:0000313|EMBL:OAA78847.1};
OS Akanthomyces lecanii RCEF 1005.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Akanthomyces;
OC Cordyceps confragosa.
OX NCBI_TaxID=1081108 {ECO:0000313|EMBL:OAA78847.1, ECO:0000313|Proteomes:UP000076881};
RN [1] {ECO:0000313|EMBL:OAA78847.1, ECO:0000313|Proteomes:UP000076881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCEF 1005 {ECO:0000313|EMBL:OAA78847.1,
RC ECO:0000313|Proteomes:UP000076881};
RX PubMed=27071652; DOI=10.1093/gbe/evw082;
RA Shang Y., Xiao G., Zheng P., Cen K., Zhan S., Wang C.;
RT "Divergent and convergent evolution of fungal pathogenicity.";
RL Genome Biol. Evol. 8:1374-1387(2016).
CC -!- SIMILARITY: Belongs to the RICTOR family.
CC {ECO:0000256|ARBA:ARBA00008878}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAA78847.1}.
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DR EMBL; AZHF01000002; OAA78847.1; -; Genomic_DNA.
DR STRING; 1081108.A0A168I6Z0; -.
DR OrthoDB; 90320at2759; -.
DR Proteomes; UP000076881; Unassembled WGS sequence.
DR GO; GO:0031932; C:TORC2 complex; IEA:InterPro.
DR GO; GO:0031929; P:TOR signaling; IEA:InterPro.
DR Gene3D; 1.10.287.160; HR1 repeat; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR011072; HR1_rho-bd.
DR InterPro; IPR036274; HR1_rpt_sf.
DR InterPro; IPR028268; Pianissimo_fam.
DR InterPro; IPR028267; Pianissimo_N.
DR InterPro; IPR029453; Rictor_IV.
DR InterPro; IPR029451; RICTOR_M.
DR InterPro; IPR029452; RICTOR_V.
DR PANTHER; PTHR13298; CYTOSOLIC REGULATOR PIANISSIMO; 1.
DR PANTHER; PTHR13298:SF11; RAPAMYCIN-INSENSITIVE COMPANION OF MTOR; 1.
DR Pfam; PF02185; HR1; 1.
DR Pfam; PF14663; RasGEF_N_2; 1.
DR Pfam; PF14666; RICTOR_M; 1.
DR Pfam; PF14664; RICTOR_N; 1.
DR Pfam; PF14668; RICTOR_V; 1.
DR SMART; SM00742; Hr1; 1.
DR SMART; SM01303; RasGEF_N_2; 1.
DR SMART; SM01307; RICTOR_M; 1.
DR SMART; SM01308; RICTOR_N; 1.
DR SMART; SM01310; RICTOR_V; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR SUPFAM; SSF46585; HR1 repeat; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000076881}.
FT DOMAIN 119..188
FT /note="REM-1"
FT /evidence="ECO:0000259|SMART:SM00742"
FT DOMAIN 250..625
FT /note="Rapamycin-insensitive companion of mTOR N-terminal"
FT /evidence="ECO:0000259|SMART:SM01308"
FT DOMAIN 704..928
FT /note="Rapamycin-insensitive companion of mTOR middle"
FT /evidence="ECO:0000259|SMART:SM01307"
FT DOMAIN 1117..1189
FT /note="Rapamycin-insensitive companion of mTOR"
FT /evidence="ECO:0000259|SMART:SM01310"
FT REGION 1..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 176..224
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1336..1430
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..64
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 71..91
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 183..224
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1336..1350
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1351..1365
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1374..1389
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1430 AA; 159621 MW; B850FABBE461F6AE CRC64;
MLANSSDVGP KGGAGQQPGQ TPQPQTGRSS FDREGSSGLQ PPNGAANAAS TRNLSTSALS
FGPRGSSLNP AAGPGSFSSE LRSQMMSSRA GSRLDVGSMY AGGVMDKVME ESPDYAPELQ
LLQLKDKLSR EMKIKEGSEN MLEALNVKKA KQTKDQRQRV EAELSASSLR IRELRRKITD
TQQQRTRPAT PTRTWTQDSS VSNGARSNQS PTKSNAGESD IDETTESPSF ALAELLQALE
VEGMMPEYYV SRANQLVGLF KRHPAIKYDL VWAIFGMRMQ MMLLSESREV VAAGYRVTRY
AISDLASLKK IRDLNTDFLV VRSLNNYRKA DVEREQALKF VRAFLDVKDG VKEISRAVVR
TIVAVAEQGD DRRATVPAID QNVDRLRPIC IETLAEILVR DPPLLVASGG LGPLSDALSE
GSYKASESLT SVFLFLLDTP QKRKYLQPSY GLDALFTAFT DPLGTNEIIL KQSCRAVSVA
VRSWSGIMTL SMYDFRPIRS LVYSMLLPSE NVRETVLDLL FSILRIKPPA WATSFLAGRR
LTTYGRVVNL KSGDGKEKPS PYMEEDGSEQ NFVDHYTALI LAILIKAGLL HSLLQIAQTE
EDPMLKRKIS LLLSEVLKLA SRLLPPSWSA ELQLLPELFK AATDFGNDEH FVASSIVYQI
SSVSKTLYRS APSETMAGIL PSSDSMVDLT ALEGQPRANN ALYLDDTTFR QLLIDSGVLN
SSNYAKWDWE IIMKIIDGPL QNGKRLEEVV RASKWMKRIM SFYRPFKYKF AEIKNTRNTQ
KYVQAGCALM HSLLQSNEGV NILADSKLVR QIAECLAQCD PTSGLTAQSP LFAKDRLTDT
LCNGYFAMLG VLTGDPKGLM LLERWKMFNM MYHIVDLKQR PDLIKLLLTN FDYTLQGHHR
VLLAKALIAG TKDIRIYATD ALRKCTLRRP AATNALGDVS DSRWAIQLLS TQLYDPEIDV
CATAVKILEK ACNRKTYLEY VVECRPALDH LGEIGAPLLL RFLSTSIGYH YLDGLDYISN
EMDDWFLGRN DSYVSVIEAS LAKSFLMDAD EQGQQSTMFD EAEPGADFHD NHVPPHFYRE
LTRTTEGCKL LRDKGHFDEF AATIRDHGMQ AEDPELVTKV KGCMWAVGNV GCMELGAPFL
EASDVVEQII RIAESHQVMS LRGTAFFVLG LISRSTHGLE ILSEHGWDAN TTPMGNSLGY
CIPTDLNKLL SLKPWNHIGA SSITLPLTQR TIREPPPAQA SKPPKENAEP TPLITDEEVN
ARIVELLVDL GSTVLYKRAV TELQKLKQRK PSAFRSIDFF KYVMGLMEWN HYRLGVRRMV
IDLFDKNVMR QIVFEESDEE NEEANSEDES DQSEVISKRT QKNEQQRQKV QQQPKSGKKA
EEAQEEDGEG HSSGNSLNSD DNRTERQRSV SEPTEYLRTS MLPPPLNLGR
//
