ID A0A168IC93_CORDF Unreviewed; 346 AA.
AC A0A168IC93;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Dihydroflavonol-4-reductase {ECO:0000313|EMBL:OAA79069.1};
GN ORFNames=LEL_02555 {ECO:0000313|EMBL:OAA79069.1};
OS Akanthomyces lecanii RCEF 1005.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Akanthomyces;
OC Cordyceps confragosa.
OX NCBI_TaxID=1081108 {ECO:0000313|EMBL:OAA79069.1, ECO:0000313|Proteomes:UP000076881};
RN [1] {ECO:0000313|EMBL:OAA79069.1, ECO:0000313|Proteomes:UP000076881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCEF 1005 {ECO:0000313|EMBL:OAA79069.1,
RC ECO:0000313|Proteomes:UP000076881};
RX PubMed=27071652; DOI=10.1093/gbe/evw082;
RA Shang Y., Xiao G., Zheng P., Cen K., Zhan S., Wang C.;
RT "Divergent and convergent evolution of fungal pathogenicity.";
RL Genome Biol. Evol. 8:1374-1387(2016).
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. Dihydroflavonol-4-reductase subfamily.
CC {ECO:0000256|ARBA:ARBA00023445}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAA79069.1}.
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DR EMBL; AZHF01000002; OAA79069.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A168IC93; -.
DR STRING; 1081108.A0A168IC93; -.
DR OrthoDB; 1200131at2759; -.
DR Proteomes; UP000076881; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd05227; AR_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10366:SF564; 3BETA_HSD DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10366; NAD DEPENDENT EPIMERASE/DEHYDRATASE; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000076881}.
FT DOMAIN 6..270
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 346 AA; 37039 MW; FA5395AAAF6D8B6C CRC64;
MAAETILLTG GSGFIAAHIL EQLLAKGHTV ITTVRSQSKA DTIAAAYPEL VASQRLTVVP
VGDIAVPTAF DDVLARHGAS LAAVLHTASP FHYNFSDAQT ELIDPAVNGT TGILRGIKAH
APHVRRVVVT SSFAAILDAS KALDHGVVYT ERSWNPNTAR DAAENKMAGY RVSKTLAERA
AWDFVEAEKP AFDLVTVNPP LVFGPVAHHL ATPDSINTSN ERVVALLQGK WKSEIPETGT
MVLWIDVRDV AAAHVRALET PAAGGKRLFI VGGRFDNRQV ADIVYKNFPD RRDAVPGPDV
KGGEAPPAEK LFQIDNSVTN KVLGIEWTSL EKSITDLVAS LKGLNI
//
